Gene Information

Name : topB (HELO_2301)
Accession : YP_003897370.1
Strain : Halomonas elongata DSM 2581
Genome accession: NC_014532
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1481787 - 1483730 bp
Length : 1944 bp
Strand : -
Note : High confidence in function and specificity

DNA sequence :
ATGCGCCTGATCATCGCCGAGAAGCCCAGCCTGGCCCGCGCCATCGCCAATGCCCTGCCTGCCTCGCCGCGCCGGGAGGA
AGGCGCCCTGGTGGCCGGAGATACCGTCGTCACCTGGTGCCTCGGCCACCTGCTGGAACAGGCGCCACCGGATGCCTACG
ACCCGGCCCTCAAGACCTGGCGGCTCGACAGCCTGCCGATCCTCCCGGATCACTGGAAGCTCATGCCGCGCCCCAAGGCA
CGCGGCCAGTTGGCGGTGATCCGTCGATTGCTGAAGAGCGCCGACCAGGTGGTCCACGCCGGTGACCCGGATCGCGAAGG
CCAGTTGCTGGTCCAGGAAGTGATCGAGCACCTCGGCTGGAAGCGCGACGTGGCACGCCTGCTGGTCAGCGATCTCAACC
CGCCGGCGGTCAAGCGTGCTCTCGAGCGTCTCGAGGACAATCGGCGCTATGCCTCGCTCTACCGCGCCGCCCAGGCGCGT
GCCAGGGCGGATTGGCTGTACGGCATCAACCTGACCCGAGCCTGGACGCTGGTCGGGCGCCAGGCCGGACACGACGGCGT
GCTCTCGGTGGGTCGTGTGCAGACGCCGGTGCTCGGCCTGGTGGTCCGGCGCGACGCCGAGATCCGCGACTTCGAGCCGC
GCCCCTTCTTCGTGCTGTGGGTCGATCTGGTGGTCTCCCGAGGCCAGTTGCGCGCCTGGTGGGTGCCAGGCGACACTCAC
CGGCTGGACGACCAGGGGCGCCTGCTCGACCGAGCCCCGGCCGCCGCCCTGGCCGACCGACTGCCCGGCGCCGAGGGCCG
CCTGGACAGCCTGGCCAGTCGCGACAAGCGCCAGGCGGCCCCGCTGCCCTACTCGCTGTCGGCCCTTCAGGTCGACGCCG
CACGCCGCCACGGGCTCTCGGCCAAGGCGGTGCTGGACGTCTGCCAGCGCCTCTATGAGCGCCACCAGTTGATAACCTAT
CCACGCTCGGACTGCCGCTATCTGCCCGAGGAGCACTTCGCCCAGGCGCAGCGCACCCTGAGCGGCGCATGCCGTAACGA
CGAGACCCTGAGCCGCTGGCTGGCCGGAGCCGACTTTTCCCGTCGCTCCAAGGCCTGGGACGACAAGAAGGTCGGCGCTC
ACCACGCCCTGGCCCCCACCGGCAAGCCCGCCGACCTCGATCGGCTGTCGCGCCAGGAAGCCGACGTCTTCCGCCTGATT
GCCCGCAACGTGCTGGCCCAGTTCTACCCGGCCCTGCAGACCCGTGAGGTCAAGGCCGAATTCCTGATCGCCGGGGAACG
CTTCCGCGCACGCGGCCAGGAAGTGCTCGAACCCGGCTGGAAGCCCTTGTTCACCACCCGTGACGAGGCACCGCCCCTGC
CGCCACTCAGCGAAGGCGAAGCCTGCCGTGTCGAGCAGGCCGGCGTGGAGGACCGCGAGACCCGGCCGCCCGAACACTTC
ACCGACGCCAGCCTGATCAAGGCGATGATGAACATCGCCCGCTACGTGGACGACCCGGCGATCCGCCGCACCCTGCGCGA
CTCCGACGGTCTCGGCACCGAGGCGACCCGCGCCGGCATCATCGAGACGCTCCTGGAGCGCGGCTATCTAGTACGCGAGG
GCAAGAGCCTCAAGGCCAGCCGGCTCGGCAGCGCCCTGATCGCCTCGTTGCCGGAAGCCGTGGGCCGCCCCGAGCGTACC
GCCCAATGGGAACAACGCCTGGCGAACATCGCCGAGCAAGACGATGCGCCAGCGCCCTTCCTCGAAGGACTGATCGACGA
TTTGCGCGGCCTGCTCGGTCACGCCGACGCCGGACGTGTGCGCAGCGCCCTGAGCGAGGCCCGAGGGCCCGAGCCTAAAG
CGAGCAAGCCCGCCCGCGGCCGGGGGCGAAGCACCAAGCGCGGCAGTGGTCAGCGCCGCCAAGGCAAGGGCACACGACGT
GCAGCGGGAGGCAAGCGCCAATGA

Protein sequence :
MRLIIAEKPSLARAIANALPASPRREEGALVAGDTVVTWCLGHLLEQAPPDAYDPALKTWRLDSLPILPDHWKLMPRPKA
RGQLAVIRRLLKSADQVVHAGDPDREGQLLVQEVIEHLGWKRDVARLLVSDLNPPAVKRALERLEDNRRYASLYRAAQAR
ARADWLYGINLTRAWTLVGRQAGHDGVLSVGRVQTPVLGLVVRRDAEIRDFEPRPFFVLWVDLVVSRGQLRAWWVPGDTH
RLDDQGRLLDRAPAAALADRLPGAEGRLDSLASRDKRQAAPLPYSLSALQVDAARRHGLSAKAVLDVCQRLYERHQLITY
PRSDCRYLPEEHFAQAQRTLSGACRNDETLSRWLAGADFSRRSKAWDDKKVGAHHALAPTGKPADLDRLSRQEADVFRLI
ARNVLAQFYPALQTREVKAEFLIAGERFRARGQEVLEPGWKPLFTTRDEAPPLPPLSEGEACRVEQAGVEDRETRPPEHF
TDASLIKAMMNIARYVDDPAIRRTLRDSDGLGTEATRAGIIETLLERGYLVREGKSLKASRLGSALIASLPEAVGRPERT
AQWEQRLANIAEQDDAPAPFLEGLIDDLRGLLGHADAGRVRSALSEARGPEPKASKPARGRGRSTKRGSGQRRQGKGTRR
AAGGKRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 5e-110 42
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 5e-110 42
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-110 42