Gene Information

Name : pmrA (Dda3937_00526)
Accession : YP_003884868.1
Strain : Dickeya dadantii 3937
Genome accession: NC_014500
Putative virulence/resistance : Virulence
Product : response regulator of the two-component transcriptional regulatory system (PmrA-PmrB BasR-BasS)
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 4401173 - 4401841 bp
Length : 669 bp
Strand : +
Note : Fe(III)-responding signal transduction system; alternative name pmrA in Salmonella; PmrA is phosphorylated by the sensor-histidine kinase PmrB in response to Fe (III) extracellular iron concentration; PmrA confers resistance to Fe(III)-mediated killing

DNA sequence : 
ATGAAACTTTTGATTGTTGAAGATGATACGTTGTTACAGGAAGGATTATTGCAGGCGATGCGCAACGAAGGGTATGTCTG
CGATTGCGCCTCCACTGCCAAAGAAGCGGATGCCCTGATCACCAGCGCCCACTACAGCCTGGTGGTACTGGATTTGGGGT
TGCCGGATGAAGACGGCCTCACCCTGCTAAACCGCTGGCGGCGGAACCGCTACCAGCAACCGGTGTTAATTCTGACCGCC
CGCGATACCGTGGACGATCGCGTTACCGGGCTGGACGTCGGCGCAGACGATTACATGATAAAGCCCTTTGCGCTGAGCGA
ATTTCAGGCAAGGGTCCGCGCACTGATCCGCCGCCATCAGGGATCCAGCGACAGCTGGATCCGGGTAGACAACATCACGC
TCGATCTCAACAATCAACAGGTCATGCTGGACGATAAACCGATCGTCCTGACCCCCAAAGAGTTCGCCATTCTGTCCCGA
CTGATCCTCAAGGCCGGTTCACAGGTACACCGTGAAGTGCTGCATCAGGACCTTTACAGCTGGGACGACGACCCCTCCTC
CAATTCGCTGGAAGTGCATATCCACAACCTGCGGCAGAAGATCGGCAAAAATCGGATTAAGACCCTGCGTGGCTTCGGTT
ATCTGCTGACCAAAGGGGACCAGACATGA

Protein sequence : 
MKLLIVEDDTLLQEGLLQAMRNEGYVCDCASTAKEADALITSAHYSLVVLDLGLPDEDGLTLLNRWRRNRYQQPVLILTA
RDTVDDRVTGLDVGADDYMIKPFALSEFQARVRALIRRHQGSSDSWIRVDNITLDLNNQQVMLDDKPIVLTPKEFAILSR
LILKAGSQVHREVLHQDLYSWDDDPSSNSLEVHIHNLRQKIGKNRIKTLRGFGYLLTKGDQT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 7e-35 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pmrA YP_003884868.1 response regulator of the two-component transcriptional regulatory system (PmrA-PmrB BasR-BasS) BAC0487 Protein 1e-84 83
pmrA YP_003884868.1 response regulator of the two-component transcriptional regulatory system (PmrA-PmrB BasR-BasS) NC_002516.2.879194.p Protein 2e-31 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pmrA YP_003884868.1 response regulator of the two-component transcriptional regulatory system (PmrA-PmrB BasR-BasS) VFG0473 Protein 4e-67 61