Gene Information

Name : hrcR (Dda3937_00615)
Accession : YP_003883246.1
Strain : Dickeya dadantii 3937
Genome accession: NC_014500
Putative virulence/resistance : Virulence
Product : type III secretion inner membrane protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4790
EC number : -
Position : 2658917 - 2659570 bp
Length : 654 bp
Strand : +
Note : E. coli containing D. dadantii hrp cluster is capable of secreting an exogenous effector into tobacco, eliciting a hypersensitive response

DNA sequence : 
ATGACCTCGGGCAGCTTCGACCCGGTGATGTTCGCCCTGTTTCTGGGTGCGTTGTCGCTGATTCCGCTGATGATGATCGT
CTGCACCTGCTTTCTTAAAGTGTCTATGGTGCTGATGATTACCCGCAACGCCATCGGGGTGCAGCAGGTGCCACCCAACA
TGGCGTTGTACGGTATCGCGCTCGCCGCCACGCTGTTCGTGATGGCGCCGGTATTCAGCGACATCAAACAGCGATTTCAG
GACGCGCCGGTGGATTTCAGCAGTCTCGACGCGCTGGAAAGCAGCGTGACCAAAGGCATCGAACCGTTGCAGAAATTCAT
GTCGCGCAACACCGATCCGGACATTCTGACCCACCTGCATGAAAACAGCCTGCGAATGTGGCCGGCGTCGATGTCCGAAA
AGATCACCACCCAAAACATTCTGCTGGTGCTGCCGGCCTATGTGCTGTCGGAGCTGCAAGCCGGGTTCAAGATCGGTTTT
CTGATTTACATCCCGTTTATCGTTATCGACCTGATTGTCTCCAACGTGCTGCTGGCGTTGGGGATGCAAATGGTGGCGCC
CACCACCCTTTCGCTGCCGCTCAAGCTGCTGCTGTTCGTGCTGGTCAACGGCTGGACGCGCCTGCTCGACGGCCTGTTCT
ACAGCTATCTGTGA

Protein sequence : 
MTSGSFDPVMFALFLGALSLIPLMMIVCTCFLKVSMVLMITRNAIGVQQVPPNMALYGIALAATLFVMAPVFSDIKQRFQ
DAPVDFSSLDALESSVTKGIEPLQKFMSRNTDPDILTHLHENSLRMWPASMSEKITTQNILLVLPAYVLSELQAGFKIGF
LIYIPFIVIDLIVSNVLLALGMQMVAPTTLSLPLKLLLFVLVNGWTRLLDGLFYSYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcR AAB06005.2 HrcR Virulence Hrp PAI Protein 8e-78 79
hrcR ABA47279.1 HrcR Virulence S-PAI Protein 5e-65 73
hrcR ABQ88359.1 HrcR Virulence Hrp PAI Protein 3e-66 72
hrpW AAB05075.1 HrpW Virulence Hrp PAI Protein 3e-66 72
hrcR AAT96303.1 HrcR Virulence S-PAI Protein 2e-60 71
hrcR AAT96343.1 HrcR Virulence S-PAI Protein 2e-60 71
hrcR AAT96262.1 HrcR Virulence S-PAI Protein 2e-60 71
hrcR AAT96146.1 HrcR Virulence T-PAI Protein 3e-68 70
hrcR AAT96200.1 HrcR Virulence T-PAI Protein 2e-68 70
hrcR AAG33884.1 HrcR Virulence Hrp PAI Protein 1e-65 69
hrcR NP_791222.3 type III secretion protein HrcR Virulence Hrp PAI Protein 2e-62 68
YPO0270 YP_002345352.1 type III secretion system protein Virulence Not named Protein 9e-35 47
lscR AAO18040.1 LscR Virulence TTSS locus Protein 3e-35 46
yscR NP_456109.1 putative type III secretion protein Virulence SPI-2 Protein 4e-33 43
yscR NP_805090.1 type III secretion system protein Virulence SPI-2 Protein 4e-33 43
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 9e-34 42
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 9e-34 42
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 4e-33 42
escR AAC31528.1 L0049 Virulence LEE Protein 6e-34 42
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 6e-34 42
unnamed AAL06354.1 EscR Virulence LEE Protein 5e-33 42
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 3e-33 42
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 3e-33 42
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 2e-33 42
escR AAK26700.1 EscR Virulence LEE Protein 7e-34 41
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 1e-33 41
escR AAL57527.1 EscR Virulence LEE Protein 7e-34 41
escR CAC81847.1 EscR protein Virulence LEE II Protein 7e-34 41
escR CAI43889.1 EscR protein Virulence LEE Protein 7e-34 41
escR AAC38369.1 EscR Virulence LEE Protein 6e-33 41
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 1e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hrcR YP_003883246.1 type III secretion inner membrane protein VFG0044 Protein 1e-36 48
hrcR YP_003883246.1 type III secretion inner membrane protein VFG1773 Protein 1e-34 45
hrcR YP_003883246.1 type III secretion inner membrane protein VFG0188 Protein 3e-35 45
hrcR YP_003883246.1 type III secretion inner membrane protein VFG2338 Protein 3e-26 44
hrcR YP_003883246.1 type III secretion inner membrane protein VFG0394 Protein 1e-34 44
hrcR YP_003883246.1 type III secretion inner membrane protein VFG0827 Protein 3e-34 42
hrcR YP_003883246.1 type III secretion inner membrane protein VFG0519 Protein 1e-33 42
hrcR YP_003883246.1 type III secretion inner membrane protein VFG0715 Protein 3e-33 41