Gene Information

Name : SP670_0181 (SP670_0181)
Accession : YP_003878363.1
Strain : Streptococcus pneumoniae 670-6B
Genome accession: NC_014498
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permeae MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 158955 - 159596 bp
Length : 642 bp
Strand : +
Note : -

DNA sequence :

ATGATTGAGTTGAAAAATATTACCAAAACCATTGGGGGAAAAGTGATTTTGGATAACTTATCTCTCAGGATTGATCAGGG
GGATTTGGTAGCTATTGTTGGTAAGAGTGGTAGTGGGAAGTCGACCTTGTTAAATTTATTGGGTTTGATAGATGGTGATT
ATAGCGGACGGTATGAGATTTTTGGTCAGACAAATCTAGCGGTTAATTCTGCTAAGTCGCAAACAATAATCCGTGAACAT
ATCTCTTATCTGTTTCAAAATTTTGCCCTGATTGATGATGAAACGGTCGAGTACAATCTCATGCTGGCGCTGAAATATGT
GAAATTGCCTAAGAAAGACAAGCTCAAAAAGGTGGAAGAGATTTTAGAGAGAGTAGGTTTGTCAGCTACTTTGCATCAAA
GGGTCTCCGAGTTGTCTGGGGGCGAACAACAACGAATTGCAGTTGCTAGAGCCATCTTAAAACCCAGCCAGCTGATTTTA
GCCGATGAACCTACAGGTTCGCTGGATCCTGAAAATAGAGATTTGGTCTTGAAGTTTCTCTTAGAGATGAATCGAGAAGG
GAAAACAGTCATTATTGTGACCCACGATGCTTATGTAGCCCAACAATGTCATCGTGTCATTGAATTGGGCGAGGGAAAAT
GA

Protein sequence :

MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLLNLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREH
ISYLFQNFALIDDETVEYNLMLALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
Spaf_1862	YP_006310627.1	amino acid ABC transporter ATP-binding protein	Not tested	FWisland_2	Protein	3e-51	61

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
SP670_0181	YP_003878363.1	macrolide export ATP-binding/permeae MacB	NC_012469.1.7686946.	Protein	1e-86	100
SP670_0181	YP_003878363.1	macrolide export ATP-binding/permeae MacB	CP003583.1.gene613.p	Protein	5e-31	45