Gene Information

Name : SP670_1157 (SP670_1157)
Accession : YP_003879320.1
Strain : Streptococcus pneumoniae 670-6B
Genome accession: NC_014498
Putative virulence/resistance : Resistance
Product : TetM protein
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0480
EC number : -
Position : 1074324 - 1076243 bp
Length : 1920 bp
Strand : -
Note : -

DNA sequence :
ATGAAAATTATTAATATTGGAGTTTTAGCTCATGTTGATGCGGGAAAAACTACCTTAACAGAAAGCTTATTATATAACAG
TGGAGCGATTACAGAATTAGGAAGCGTGGACAAAGGTACAACGAGGACGGATAATACGCTTTTAGAACGTCAGAGAGGAA
TTACAATTCAGACAGGAATAACCTCTTTTCAGTGGGAAAATACGAAGGTGAACATCATAGACACGCCAGGACATATGGAT
TTCTTAGCAGAAGTATATCGTTCATTATCAGTTTTAGATGGGGCAATTCTACTGATTTCTGCAAAAGATGGCGTACAAGC
ACAAACTCGTATATTATTTCATGCACTTAGGAAAATGGGGATTCCCACAATCTTTTTTATCAATAAGATTGACCAAAATG
GAATTGATTTATCAACGGTTTATCAGGATATTAAAGAGAAACTTTCTGCCGAAATTGTAATCAAACAGAAGGTAGAACTG
TATCCTAATATGTGTGTGACGAACTTTACCGAATCTGAACAATGGGATACGGTAATAGAGGGAAACGATGACCTTTTAGA
GAAATATATGTCCGGTAAATCATTAGAAGCATTGGAACTCGAACAAGAGGAAAGCATAAGATTTCAGAATTGTTCTCTGT
TCCCTCTTTATCATGGAAGTGCAAAAAGTAATATAGGGATTGATAACCTTATAGAAGTTATTACTAATAAATTTTATTCA
TCAACACATCGAGGTCCGTCTGAACTTTGCGGAAATGTTTTCAAAATTGAGTATTCGGAAAAAAGACAGCGTCTTGCATA
TATACGTCTTTATAGTGGCGTACTGCATTTGCGAGATTCGGTTAGAATATCGGAAAAGGAAAAAATAAAAATTACAGAAA
TGTATACTTCAATAAATGGTGAATTATGTAAAATCGATAAGGCTTATTCCGGGGAAATTGTTATTTTGCAGAATGAGTTT
TTGAAGTTAAATAGTGTTCTTGGAGATACAAAGCTATTGCCACAGAGAGAGAGAATTGAAAATCCCCTCCCTCTGCTGCA
AACGACTGTTGAACCGAGCAAACCTCAACAAAGGGAAATGTTACTTGATGCACTTTTAGAAATCTCCGACAGTGACCCGC
TTCTGCGATATTATGTGGATTCTGCGACACATGAAATCATACTTTCTTTCTTAGGGAAAGTACAAATGGAAGTGACTTGT
GCTCTGCTGCAAGAAAAGTATCATGTGGAGATAGAAATAAAAGAGCCTACAGTCATTTATATGGAAAGACCGTTAAAAAA
AGCAGAGTATACCATTCACATCGAAGTTCCACCGAATCCTTTCTGGGCTTCCATTGGTCTATCTGTAGCACAGCTTCCAT
TAGGGAGCGGAGTACAGTATGAGAGCTCGGTTTCTCTTGGATACTTAAATCAATCGTTTCAAAATGCAGTTATGGAGGGG
ATACGCTATGGCTGTGAACAAGGATTGTATGGTTGGAATGTGACGGACTGTAAAATCTGTTTTAAGTATGGCTTATACTA
TAGCCCTGTTAGTACCCCAGCAGATTTTCGGATGCTTGCTCCTATTGTATTGGAACAAGTCTTAAAAAAAGCTGGAACAG
AATTGTTAGAGCCATATCTTAGTTTTAAAATTTATGCGCCACAGGAATATCTTTCACGAGCATACAACGATGCTCCTAAA
TATTGTGCGAACATCGTAGACACTCAATTGAAAAATAATGAGGTCATTCTTAGTGGAGAAATCCCTGCTCGGTGTATTCA
AGAATATCGTAGTGATTTAACTTTCTTTACAAATGGACGTAGTGTTTGTTTAACAGAGTTAAAAGGGTACCATGTTACTA
CCGGTGAACCTGTTTGCCAGCCCCGTCGTCCAAATAGTCGGATAGATAAAGTACGATATATGTTCAATAAAATAACTTAG

Protein sequence :
MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMD
FLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYS
STHRGPSELCGNVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEF
LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTC
ALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVAQLPLGSGVQYESSVSLGYLNQSFQNAVMEG
IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPK
YCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU05_0922 YP_001198287.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 96
SSU98_0928 YP_001200485.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 96
tetO AFJ97266.1 truncated tetracycline resistant protein Not tested Not named Protein 2e-163 75
tet(W) YP_005160006.1 tetracycline resistance protein Not tested Not named Protein 0.0 69

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SP670_1157 YP_003879320.1 TetM protein X04388.gene.p01 Protein 0.0 98
SP670_1157 YP_003879320.1 TetM protein M85225.gene.p01 Protein 0.0 98
SP670_1157 YP_003879320.1 TetM protein NC_009782.5559075.p0 Protein 0.0 95
SP670_1157 YP_003879320.1 TetM protein NC_002758.1120355.p0 Protein 0.0 95
SP670_1157 YP_003879320.1 TetM protein AM180355.1.gene636.p Protein 0.0 93
SP670_1157 YP_003879320.1 TetM protein L09756.gene.p01 Protein 0.0 79
SP670_1157 YP_003879320.1 TetM protein AJ295238.gene.p01 Protein 0.0 72
SP670_1157 YP_003879320.1 TetM protein AJ222769.gene.p01 Protein 0.0 69
SP670_1157 YP_003879320.1 TetM protein DQ294299.gene.p01 Protein 0.0 69
SP670_1157 YP_003879320.1 TetM protein AY485126.gene.p01 Protein 0.0 69
SP670_1157 YP_003879320.1 TetM protein FN594949.1.gene24.p0 Protein 0.0 67
SP670_1157 YP_003879320.1 TetM protein L42544.gene.p01 Protein 1e-125 44
SP670_1157 YP_003879320.1 TetM protein AJ514254.gene.p01 Protein 5e-121 43
SP670_1157 YP_003879320.1 TetM protein Z21523.gene.p01 Protein 5e-109 41