Gene Information

Name : erm(TR) (SPAP_0896)
Accession : YP_003876487.1
Strain : Streptococcus pneumoniae AP200
Genome accession: NC_014494
Putative virulence/resistance : Resistance
Product : dimethyladenosine transferase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0030
EC number : -
Position : 856174 - 856905 bp
Length : 732 bp
Strand : +
Note : Operon 400 Gene 1 COG0030 Dimethyladenosine transferase (rRNA methylation)

DNA sequence : 
ATGAAACAGAAAAACCCGAAAAATACGCAAAATTTCATTACATCTAAAAAGCATGTAAAGGAAATATTAAAATATACGAA
TATCAATAAACAAGATAAAATAATAGAAATTGGGTCAGGAAAAGGACATTTTACCAAGGAACTTGTGGAAATGAGTCAAC
GGGTGAATGCTATAGAGATTGATGAAGGTTTATGTCATGCCACGAAAAAAGCAGTTGAACCTTTTCAGAATATAAAAGTT
ATTCATGAGGATATTTTGAAGTTTAGCTTTCCTAAAAATACAGACTATAAAATATTTGGTAATATTCCCTACAATATTAG
TACTGATATTGTAAAAAAGATTGCTTTTGATAGTCAAGCGAAATATAGCTACCTTATTGTAGAGAGGGGATTTGCTAAAA
GGTTGCAAAATACCCAACGAGCTTTAGGTTTGCTGTTAATGGTGGAAATGGATATAAAAATTCTTAAAAAAGTGCCACGA
GCATATTTTCACCCTAAGCCTAATGTAGATTCTGTATTGATTGTACTTGAAAGGCATAAACCATTTATTTTAAAGAAGGA
CTACAAAAAGTATAGATTTTTCGTTTATAAATGGGTAAACAGGGAATATCATGTTCTTTTTACTAAAAATCAATTAAGAC
AGGTGCTGAAGCATGCGAATGTTACTGATCTTGATAAATTATCCAATGAACAATTTTTGTCTGTTTTCAATAGTTACAAA
TTATTTCAATAA

Protein sequence : 
MKQKNPKNTQNFITSKKHVKEILKYTNINKQDKIIEIGSGKGHFTKELVEMSQRVNAIEIDEGLCHATKKAVEPFQNIKV
IHEDILKFSFPKNTDYKIFGNIPYNISTDIVKKIAFDSQAKYSYLIVERGFAKRLQNTQRALGLLLMVEMDIKILKKVPR
AYFHPKPNVDSVLIVLERHKPFILKKDYKKYRFFVYKWVNREYHVLFTKNQLRQVLKHANVTDLDKLSNEQFLSVFNSYK
LFQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ermA BAC57474.1 rRNA methylase Not tested Type-IIIinv SCCmec Protein 1e-95 82
ermA BAA82205.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 1e-95 82
ermA1 YP_039522.1 rRNA adenine N-6-methyltransferase 1 Not tested Type-II SCCmec Protein 2e-95 82
ermA NP_370576.1 rRNA methylase Not tested Type-II SCCmec Protein 2e-95 82
ermA NP_373288.1 rRNA methylase Not tested Type-II SCCmec Protein 2e-95 82
ermA-3 YP_190052.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 2e-95 82
unnamed BAB47663.1 rRNA adenine N-6-methyltransferase Not tested Type-III SCCmec Protein 3e-95 82
unnamed BAC53825.1 rRNA adenine N-6-methyltransferase Not tested SRImec-III and SCCmec-III region Protein 3e-95 82
ermC NP_273130.1 rRNA adenine N-6-methyltransferase Not tested IHT-A Protein 2e-63 60

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_009782.5559087.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002758.1121630.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002952.2859615.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002745.1123579.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002745.1124852.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_009782.5559229.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002758.1120012.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002952.2859614.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002745.1122822.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002745.1124324.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_002745.1125313.p0 Protein 7e-96 82
erm(TR) YP_003876487.1 dimethyladenosine transferase AJ313523.1.orf0.gene Protein 4e-82 71
erm(TR) YP_003876487.1 dimethyladenosine transferase M64090.gene.p01 Protein 3e-65 62
erm(TR) YP_003876487.1 dimethyladenosine transferase V01278.gene.p01 Protein 9e-64 60
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_010685.6295744.p0 Protein 8e-64 60
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_010686.6295746.p0 Protein 8e-64 60
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_007792.3912746.p0 Protein 3e-63 59
erm(TR) YP_003876487.1 dimethyladenosine transferase NC_007209.3523503.p0 Protein 9e-64 59
erm(TR) YP_003876487.1 dimethyladenosine transferase M15332.gene.p01 Protein 4e-63 56
erm(TR) YP_003876487.1 dimethyladenosine transferase AM180355.1.gene2259. Protein 3e-50 49
erm(TR) YP_003876487.1 dimethyladenosine transferase AM903082.gene3.p01 Protein 5e-51 49
erm(TR) YP_003876487.1 dimethyladenosine transferase AM180355.1.gene2254. Protein 3e-50 49
erm(TR) YP_003876487.1 dimethyladenosine transferase AM410044.gene14.p01 Protein 5e-51 49