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Name : SPAP_0887 (SPAP_0887) Accession : YP_003876478.1 Strain : Streptococcus pneumoniae AP200 Genome accession: NC_014494 Putative virulence/resistance : Unknown Product : topoisomerase IA Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : - Position : 838300 - 840021 bp Length : 1722 bp Strand : + Note : Operon 395 Gene 1 COG0550 Topoisomerase IA DNA sequence : ATGAAATTAGTAATAGCAGAAAAGCCAAGTGTAGCAGTTACAATTGCAAAAGTAATTGGAGCAAGAACAAGAAAAAACGG ATATTATGAGGGAGGTGGCTACATTGTTTCTTGGTGTGTAGGTCATTTAATTCAAATGGCAAGACCAGATAAGATAGATG AAAAATGGAAGAAATGGGCAATAGACACTCTTCCTATAATCCCAGAAGAATATATTTATGAAGTATCTAAAAGCACTAAG AAACAATATGGAGTTTTAAAGACACTTTTAAACGATAAGAATATCGACACAGTTATAAATGCTTGTGATGCTGGAAGAGA GGGAGAACTTATCTTTAGGCTTGTATATAATCAAGCTAAATGTAAGAAGAAGATTCAAAGACTTTGGATATCTTCAATGG AAAACAAAGCTATTGAAGATGGCTTTAGAAATCTTAAAGATGGAGAAAACTTTGAAGACTTATATAGATCGGCAAGTGCA AGAGCTATTGCGGATTGGCTGGTAGGAATGAATTTAAGTAGGCTATATTCTTGCATTTACAAGGAAACATATTCTGTTGG TAGAGTACAAACACCAACTCTATATTTAATAGCTAAAAGAGATAGTGAAATAAACCTATTTAAGAAGCAAAAATATTATA CGGTAGACCTATCTTATGGAGGATTGAAGCTTGTATCTGATAGGATTGATAGAATTGAAGTTGCAGAACAACTATTAAAC TTGCTAGAAGATGAAATAGTTATTACAGAGGTAGAAGATAAAGAAATAAGTACAAAACCAGATAAACCTTATGATCTCAC TACCTTACAAAGAGAAGCAAATAAATATTTTGGATATTCAGCAAATGACACTTTAAATCTGGCACAAGGCTTGTATGAAA AAAAGCTAATCACATATCCAAGAACGGATAGTAGGTATTTAACCAATGATATGGTTACTACTATGAAAGAATTATTAGAA GGACTTGAAGAAGGTTTTAAAATCAATGAATCAAACTTTAAGTCTATTTTTAATTCATCTAAGGTTACAGACCACTATGC AATTATTCCTACTATATCAGGTATTGGAAAAGCCAAAGATTTATCTGATAAAGAAAGCAAAATCTATAATCTAATTAAGG ATAAATTACTTGCTTCATGTTCGGATAACTTAAAGGAATCTAGTAGAAAAATCAGATATAAATATGACAAGTTTAACTTT AGTGCAAGTGGCAAGACTATAATCGATGAAGGTTATGCCAAGTATTTAAAGCCTTATGGGAAGGAAAGACAAGAAAATGA ATTACCAGATGTAAAGACTGGAGATAAAATTAAGCTAACTTCTAAAAATATATCGGAGAAATTTACAAAAGCCCCAAGTC ATTATAATGAAGATACACTTTTAAAGGCTATGGAGAATGCAGGAGTAGAATCCTTGGATAAAGATATAGAAGTGGAGAGA AAAGGTTTAGGAACACCAGCCACAAGAGCAGGAATTATCGAAAATCTTATCCATAAGGACCTTATAAGAAGAGATAAGAA AAATCTACTTGTAACAGAAAAAGGCAATAGGCTTGTATCGATTGTAGAAGATAAGTTTAAATCAGCTGAAACAACATCTG AATGGGAAATGAAACTTGCAAAGATTAGCTCTGGTGAAGTAGATAAAGAAGACTTTTTAAGAGAGATCGAAGATAGTATA AGGGAGCTTGTAGATAGGTACAAGAATAATCTAAATGAATAA Protein sequence : MKLVIAEKPSVAVTIAKVIGARTRKNGYYEGGGYIVSWCVGHLIQMARPDKIDEKWKKWAIDTLPIIPEEYIYEVSKSTK KQYGVLKTLLNDKNIDTVINACDAGREGELIFRLVYNQAKCKKKIQRLWISSMENKAIEDGFRNLKDGENFEDLYRSASA RAIADWLVGMNLSRLYSCIYKETYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLSYGGLKLVSDRIDRIEVAEQLLN LLEDEIVITEVEDKEISTKPDKPYDLTTLQREANKYFGYSANDTLNLAQGLYEKKLITYPRTDSRYLTNDMVTTMKELLE GLEEGFKINESNFKSIFNSSKVTDHYAIIPTISGIGKAKDLSDKESKIYNLIKDKLLASCSDNLKESSRKIRYKYDKFNF SASGKTIIDEGYAKYLKPYGKERQENELPDVKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKAMENAGVESLDKDIEVER KGLGTPATRAGIIENLIHKDLIRRDKKNLLVTEKGNRLVSIVEDKFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSI RELVDRYKNNLNE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| EFAU085_00720 | YP_008394244.1 | DNA topoisomerase III | Not tested | Not named | Protein | 6e-111 | 44 |
| topB-2 | NP_815968.1 | DNA topoisomerase III | Not tested | Not named | Protein | 2e-115 | 43 |
