Gene Information

Name : wze (SPAP_0377)
Accession : YP_003875972.1
Strain : Streptococcus pneumoniae AP200
Genome accession: NC_014494
Putative virulence/resistance : Virulence
Product : tyrosine-protein kinase Wze
Function : -
COG functional category : D : Cell cycle control, cell division, chromosome partitioning
COG ID : COG0489
EC number : -
Position : 346257 - 346946 bp
Length : 690 bp
Strand : +
Note : Operon 160 Gene 4 COG0489 ATPases involved in chromosome partitioning

DNA sequence : 
ATGCCAACGTTAGAAATCTCACAGGTGAAATTAGAACTTGCGAAAAAGGCAGAGGAATATTATAATGCTTTGTGCACGAA
CCTACAGTTAAGTGGAGATGATTTGAAAGTATTTTCTATCACTTCTGTGAAAGCAGGAGAAGGAAAAACAACGACTTCCA
CCAATATCGCTTGGGCTTTTGCGCGTGCAGGTTACAAAACGTTGCTGATTGATGCAGACATGCGTAACTCCGTTATGTCA
GGTGTCTTTAAATCAAGGGAAAGGATTACTGGACTAACAGAATTTCTATCAGGGACAACAGACCTGTCACAGGGGCTTTG
CGATACCAATATTGAGAATCTCTTTGTGATTCAGGCTGGCTCTGTGTCACCAAATCCGACAGCCCTTCTTCAAAGTAAGA
ATTTCAGCACAATGCTTGGAACCTTGCGTAAATATTTTGACTATATCGTCGTAGACACTGCTCCTATCGGTATTGTGATT
GATGCGGCTATCATTATGCAGAAATGTGATGCTTCTATTTTAGTGACGAAGGCAGGTGAAACAAAACGACGGGATCTTCA
AAAAGCGAAAGAACAGTTGGAACAAACTGGGAAGTCGTGTTTAGGAGTTGTGTTGAATAAATTCGATACTTCAGTAGAGA
AATACGGTTCTTATGGGAGTTATGGGAATTACAGGAAACAGAAAAAATAG

Protein sequence : 
MPTLEISQVKLELAKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMS
GVFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKFDTSVEKYGSYGSYGNYRKQKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpsFD YP_006310771.1 putative autophosphorylating protein tyrosine kinase Not tested FWisland_4 Protein 2e-63 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wze YP_003875972.1 tyrosine-protein kinase Wze VFG1368 Protein 1e-85 81
wze YP_003875972.1 tyrosine-protein kinase Wze VFG1349 Protein 4e-60 55