Gene Information

Name : SPAP_1474 (SPAP_1474)
Accession : YP_003877062.1
Strain : Streptococcus pneumoniae AP200
Genome accession: NC_014494
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1389618 - 1391180 bp
Length : 1563 bp
Strand : -
Note : Operon 659 Gene 1 COG0519 GMP synthase, PP-ATPase domain/subunit

DNA sequence :
ATGAGCAACATTTCAACTGATTTGCAAGATGTAGAAAAAATCATCGTATTGGACTATGGTAGCCAGTACAACCAGCTGAT
TTCACGCCGTATCCGTGAGATTGGTGTTTTTTCAGAACTAAAAAGCCATAAAATTTCAGCTGCTGAAGTTCGTGAAGTCA
ATCCTGTAGGAATTATTCTATCAGGTGGTCCAAATTCTGTATATGAAGATGGTTCATTTGATATTGACCCAGAAATCTTC
GAACTCGGAATTCCAATTTTGGGAATCTGTTATGGTATGCAGTTATTGACCCATAAACTTGGAGGAAAAGTTGTTCCTGC
AGGTGATGCTGGAAATCGTGAATACGGTCAATCAACCCTAACTCACACACCATCAGCGCTTTTTGAATCAACACCTGATG
AACAGACTGTTTTGATGAGCCATGGTGATGCGGTTACTGAGATTCCTGCTGACTTTGTTCGTACAGGTACATCAGCTGAC
TGCCCATACGCAGCCATCGAAAACCCAGATAAACACATTTACGGTATCCAATTCCACCCAGAAGTTCGTCATTCTGTATA
CGGAAATGATATCCTTCGTAACTTTGCCCTTAACATTTGTAAGGCTAAAGGTGACTGGTCAATGGATAATTTCATTGACA
TGCAGATCAAAAAAATTCGTGAAACCGTCGGTGATAAACGTGTCCTTCTTGGTCTATCAGGTGGTGTTGACTCATCTGTC
GTTGGGGTTCTTCTCCAAAAAGCGATTGGCGATCAATTGATCTGTATCTTCGTAGACCACGGTCTTCTTCGTAAAGGCGA
AGCTGATCAAGTTATGGACATGCTCGGTGGTAAGTTTGGTTTGAATATCGTCAAAGCAGACGCTGCTAAACGTTTCCTTG
ACAAACTTGCTGGCGTTTCTGATCCTGAACAAAAACGTAAAATCATTGGTAACGAGTTTGTCTATGTATTCGATGACGAA
GCAAGCAAGCTCAAAGATGTGAAATTCCTTGCTCAAGGTACTTTATATACAGATGTTATCGAGTCTGGTACGGATACAGC
TCAAACTATCAAGTCACACCACAACGTGGGTGGTCTTCCAGAAGATATGCAGTTTGAATTGATTGAACCACTCAATACTC
TTTACAAGGATGAAGTTCGTGCTCTTGGTACAGAGCTTGGTATGCCAGACCATATCGTATGGCGCCAACCATTCCCAGGA
CCAGGACTTGCTATCCGTGTCATGGGTGAAATCACTGAAGAGAAACTTGAAACCGTTCGTGAATCAGACGCTATTCTTCG
TGAAGAAATCGCTAAAGCTGGACTTGACCGCGATATTTGGCAATACTTCACTGTTAACACAGGCGTTCGTTCAGTCGGTG
TTATGGGTGACGGTCGTACGTATGACTACACGATTGCAATCCGTGCTATCACTTCTATCGATGGTATGACTGCTGATTTT
GCCAAAATTCCATGGGAAGTACTTCAAAAAATCTCAGTACGTATCGTAAATGAAGTGGATCATGTTAACCGTATCGTCTA
CGATATTACAAGTAAACCACCTGCAACAGTTGAGTGGGAGTAA

Protein sequence :
MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHKISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIF
ELGIPILGICYGMQLLTHKLGGKVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKKIRETVGDKRVLLGLSGGVDSSV
VGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLGGKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDE
ASKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHIVWRQPFPG
PGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AKIPWEVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-176 71
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-176 71
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-176 71
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-122 51