Gene Information

Name : SPAP_1164 (SPAP_1164)
Accession : YP_003876755.1
Strain : Streptococcus pneumoniae AP200
Genome accession: NC_014494
Putative virulence/resistance : Virulence
Product : cobalamin/Fe3+-siderophores ABC transporter ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 1103575 - 1104369 bp
Length : 795 bp
Strand : -
Note : Operon 527 Gene 1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

DNA sequence :
ATGAAAGGTCTGTGGTCAAATAATCTTACCTGCGGTTATGATGAAAAAATAATCTTGGAAAATATAAATATAAAAATACC
TGAAGAAAAAATATCAGTTATTATTGGGTCAAATGGTTGTGGGAAATCAACACTCATTAAAACCTTGTCTCGACTTATAA
AGCCATTAGAGGGAGAAGTATTGCTTGATAATAAATCAATTAATTCTTATAAAGAAAAAGATTTAGCAAAACACATAGCT
ATATTACCTCAATCTCCAATAATCCCTGAATCAATAACAGTAGCTGATCTTGTAAGCCGTGGTCGTTTCCCCTACAGAAA
GCCTTTTAAGAGTCTTGGAAAAGATGACCTTGAAATAATAAACAGATCAATGGTTAAGGCCAATGTTGAAGATCTAGCAA
ATAACCTAGTTGAAGAACTTTCTGGGGGTCAAAGGCAAAGAGTATGGATAGCTCTAGCCCTAGCCCAAGATACAAGTATC
CTACTTTTAGATGAGCCAACTACTTACTTGGATATCTCATATCAAATAGAACTATTAGACCTCTTGACTGATCTAAACCA
AAAATATAAGACAACCATTTGCATGATTTTGCACGATATAAATCTAACAGCAAGATACGCTGATTACCTATTTGCAATTA
AAGAAGGTAAACTTGTTGCAGAGGGAAAGCCTGAAGATATACTAAATGATAAACTAGTTAAAGATATCTTTAATCTTGAA
GCAAAAATTATACGTGACCCTATTTCCAATTCGCCTCTAATGATTCCTATTGGCAAGCACCATGTTAGCTCTTAA

Protein sequence :
MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKSTLIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIA
ILPQSPIIPESITVADLVSRGRFPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKLVAEGKPEDILNDKLVKDIFNLE
AKIIRDPISNSPLMIPIGKHHVSS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-110 99
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-110 99
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-50 45
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-47 42
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 7e-47 42
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 7e-47 42
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-47 42
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 5e-43 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPAP_1164 YP_003876755.1 cobalamin/Fe3+-siderophores ABC transporter ATPase BAC0164 Protein 3e-43 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPAP_1164 YP_003876755.1 cobalamin/Fe3+-siderophores ABC transporter ATPase VFG0925 Protein 1e-56 48
SPAP_1164 YP_003876755.1 cobalamin/Fe3+-siderophores ABC transporter ATPase VFG1042 Protein 3e-43 41