Gene Information

Name : STHERM_c09130 (STHERM_c09130)
Accession : YP_003874133.1
Strain : Spirochaeta thermophila DSM 6192
Genome accession: NC_014484
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1004851 - 1006197 bp
Length : 1347 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGGAAAGTATCTGGCCCTGGTGGAAAAGACCGAGACGGTGAAATGCAGGGGGAGGGTGAAGGCCGTACAGGGTAT
GAGGATCGAGGGGCAGGGCCCCCTCGCAGTGGTGGGTGAACTCTGCCGCATCCATCCCCCGGACGATCCTGATGCCGGGA
TATGGGCCGAGGTGATAGGTCTCAAGGGATCGACCGTCTATCTCATGGGATACCGGGACCCTGAGGGGATCCAGGTGGGG
GATGTGATAGAGGCGATGGGTGAGCCCCTCTCCATACGGGTCTCCGAAGGTCTTCTCGGCAGGGTACTCGATGCCCGCGG
CATGCCCATAGACGACAAGGGGCCCCTCCCTCCAGGGATACGGTACCCGGTGCAGGGGGGTCCTCCGCACGTACTCAAGC
GCAGACGCATAGAAGAGCAGATCGCCACGGGGATCAGGGCTCTCGACGGCCTCCTCCCCATAGGCAAGGGACAGCGTGTG
GGTGTCTTCTCAGGGAGCGGGGTGGGAAAGTCGACCCTTCTGGGGATGGTCGCCCGCAACACCAACGCGGACGTGAACGT
GATCGCCCTCATCGGCGAGCGGGGGAGGGAAGTCGCGGAGTTCATAGAGCACGATCTGGGAGAGGAGGGGCTGAAGCGCT
CGGTCGTAGTGGTGTCCACTTCCGACACCCCTGCGGTGGCGCGCTATCGAGGGGCGTTCGTGGCGGTCGCCATAGCCGAG
TACTTCCGGGATCAGGGGAAGGACGTCATGCTCCTCTTCGACTCCATCACCCGGTTCGCGAGGGCCCTCAGGGAGATGGG
GCTCGCCCTGGGGGAGTCTCCTGCGACGAGGGGCTATCCCCCTTCGGTCTTTTCCACCCTCCCCAAGCTTCTCGAGCGAT
GTGGAACATCGGAGAAGGGGACCATCACCGGGTTCTTCTCGGTCCTCGTGGAGGGGGACGACATGGACGAGCCCGTCTCC
GATGCCGTGCGTGGCATCCTCGACGGCCATGTGGTGCTCTCGAGGAGACTCGCCCAGCGGCAGCACTATCCTGCGATCGA
CGTCCTCTCATCGGTCTCGAGACTGGCTCCCAAGATCACCACCCCTCCTGTGAGGGATGCGGCGAGACGAGTCATGAGGT
GGCTCGCCGCCTATCAGGAGACCGAAGACCTCATCAACGTAGGAGCCTACGCGAGGGGGAGCAACCCGGAGGTGGACAAG
GCCATAGAGAAGCTGCCTGATATCAACGCCTTCCTGAGGCAGGAGATCGAGGAGCGGGCCCCTCTCGCCGAGACGATTCA
CCGCCTGTTTGACCTTGCGGAGATGGAGACCACGGAGGAGGAATCCGGCGACGATGAGACGGTTTAG

Protein sequence :
MFGKYLALVEKTETVKCRGRVKAVQGMRIEGQGPLAVVGELCRIHPPDDPDAGIWAEVIGLKGSTVYLMGYRDPEGIQVG
DVIEAMGEPLSIRVSEGLLGRVLDARGMPIDDKGPLPPGIRYPVQGGPPHVLKRRRIEEQIATGIRALDGLLPIGKGQRV
GVFSGSGVGKSTLLGMVARNTNADVNVIALIGERGREVAEFIEHDLGEEGLKRSVVVVSTSDTPAVARYRGAFVAVAIAE
YFRDQGKDVMLLFDSITRFARALREMGLALGESPATRGYPPSVFSTLPKLLERCGTSEKGTITGFFSVLVEGDDMDEPVS
DAVRGILDGHVVLSRRLAQRQHYPAIDVLSSVSRLAPKITTPPVRDAARRVMRWLAAYQETEDLINVGAYARGSNPEVDK
AIEKLPDINAFLRQEIEERAPLAETIHRLFDLAEMETTEEESGDDETV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-89 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-84 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-84 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-84 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 9e-84 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-83 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 9e-81 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-67 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-69 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-69 47
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-65 47
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-65 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-83 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-82 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-82 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-84 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-82 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-84 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 47
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-84 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-70 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 7e-66 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-72 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-72 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 9e-63 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 7e-69 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-76 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-69 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-70 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-69 44
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-75 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-69 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-76 43
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-76 43
escN AAK26715.1 EscN Virulence LEE Protein 5e-75 43
escN AAL57542.1 EscN Virulence LEE Protein 5e-75 43
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-75 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-75 43
escN AAC31513.1 L0034 Virulence LEE Protein 7e-76 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-75 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-76 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-75 43
escN AAC38383.1 EscN Virulence LEE Protein 6e-76 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-76 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-63 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-63 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-63 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 7e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STHERM_c09130 YP_003874133.1 hypothetical protein VFG2144 Protein 1e-92 54
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0192 Protein 2e-92 51
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0515 Protein 5e-84 50
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0390 Protein 1e-84 50
STHERM_c09130 YP_003874133.1 hypothetical protein VFG1254 Protein 1e-85 50
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0048 Protein 1e-90 48
STHERM_c09130 YP_003874133.1 hypothetical protein VFG2499 Protein 2e-75 47
STHERM_c09130 YP_003874133.1 hypothetical protein VFG2459 Protein 3e-76 45
STHERM_c09130 YP_003874133.1 hypothetical protein VFG2331 Protein 5e-73 43
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0730 Protein 4e-76 43
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0812 Protein 4e-76 43
STHERM_c09130 YP_003874133.1 hypothetical protein VFG1778 Protein 1e-66 43
STHERM_c09130 YP_003874133.1 hypothetical protein VFG0555 Protein 3e-63 41
STHERM_c09130 YP_003874133.1 hypothetical protein VFG1008 Protein 2e-62 41