Gene Information

Name : clpB1 (STHERM_c12380)
Accession : YP_003874452.1
Strain : Spirochaeta thermophila DSM 6192
Genome accession: NC_014484
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1344176 - 1346686 bp
Length : 2511 bp
Strand : -
Note : -

DNA sequence :
ATGTTTAAGGATTTGACGCAGCGCGCCCAGAAGATACTCACGGTGCTCGCCCAGGATGAGGCGAAGCGGTTTCATGCGGA
AGAACTGGAGCCGGAGCATATCATCCTCGCCATCATCCGCGAAGGGGCGGGCGTTGCCTATAGAGCGATAAAACGTCTCA
AGATCGCGCCGGAGGAGATCCAGGTCTTCGTAGAGAAGAATCTCTCCAAACAGAGGGGGAGTTTCATCCTCGGGGATGTG
CCCCTTTCCTCCAGGAGCAGGAGGGTCCTCGAGTATGCAGCCGAGGAGGCCCGCCATTTGGACGACGAATACATTGGGAC
CGAGCATCTCATGCTGGGATGTGCCCGCGACGGCGAGGGGGTGTTCACCCGGTTCCTGGCCCAGAAGGGCATCGACCTGG
AAGTCTTGAGGGAGGCCATCCTCGAGGTGAAGGGGAGTGAATCGGTGTACAACAGCTCGTGGGGGGGGAAGGAGGAACAG
GAGAAACGGAGGGGGGCCTTCCAGTCGGCTGCCTACAGAAAGAATACCCCATTGCTCGACGAGTTCTCCAGGGATCTCAC
CGAGCTCGCCCAGACGGGTAAGCTCGATCCGGTCATCGGGAGGGAGCGTGAGCTCCGTCGTATCGTCCAGATCCTGGCCC
GACGTACCAAGAACAACCCCGTGCTCATCGGTGACCCGGGGGTGGGGAAGACGGCGATCGTGGAGGCTCTCGCCCAGCGG
ATCGTGCGCGGCGAGGTGCCCGAGATACTCGAGGGCAAGCGCATACTCGTCCTCGATCTTGCGGCCCTGGTGGCGGGGAC
CAAGTACCGGGGCGAGTTCGAGGAACGGCTCAAGCGGGTGATGCGGGAGATCGTCTCGGTGAAGAACGTGGTCCTCTTCA
TCGACGAGCTCCACACCATCATTGGCGCGGGCGGTGCCGAGGGTGCCATCGACGCCTCCAACATGCTCAAGCCTGCGCTC
TCACGGGGGGAGATCCAGTGCATCGGCGCCACCACCCTGGACGAGTACCGGAAGTACATCGAAAAGGATGCGGCACTGGA
GCGTAGGTTCCAGCCCGTGTACGTTCGCGAGCCGACCATCGAGGAGACGATCCAGATCCTCGAAGGGATAAAGACGAGGT
ACGAGGATTTCCACAACGTCACCTATACGCGCAAGGCCGTGGAGGCGGCGGTGGTCCTCTCTGCCCGCTACATCACCGAA
CGCCACCTGCCCGACAAGGCCATCGATCTGCTCGACGAGGCGGGATCGCGGACCCACGTGCAGGTGCTCAACCGGCCTCA
GGAGATAGAGGAGCTTGAGAAAAAGATAGAGCAGCTCAATTCCGAGAAGATCATGCTCGTGAACACGCAGAACTACGAGC
GGGCGGCTGCGGTGAGGGACCAGGTGAACCGGCTCAAGATGGAGCTCGAGAGGCTGAAGACCGCCTGGAAGCTCGAGATC
AAGCGGACGCAGAACATCGTCGATCAGGAGGACATCCAGGAGGTGGTCTCCGACATCACCGGCATCCCGCTCGTGAGGAT
CGCGCAGAGTGAATCGGAGCGTCTCCTCCATATCGAGGAGGAACTCCACCGGAAGGTGATAAGCCAGGACGAGGCCATAA
AAGTGGTGGCATCTGCCATCCGCAGGGCGCGGACGGGGCTGAGCTCTCCAAACCGTCCCATGGGATCGTTCGTCTTCCTC
GGGCCGACCGGTGTGGGTAAGACCCTTCTCGCGAAGACCTTGGCCGAATATCTCTTCGGCGACACCTCCGCGCTCATCCG
GCTCGACATGTCGGACTTCATGGAGAAACACAACGTCTCGAGGCTCGTGGGGGCCCCTCCAGGGTATGTGGGCTACGAGG
AGGGCGGCCTCCTCACGGAGAAGGTGCGTCATCGGCCCTATTCAGTGATACTCTTCGACGAGATAGAGAAGGCTCATCCG
GATGTCTTCAACATCCTCCTTCAGATCCTCGAAGAGGGGGAACTGCAGGACAACCTGGGACACAGGGTCTCCTTCCGGAA
CGCCGTACTCATCATGACCTCGAACGCGGGTGCCAGGGAGATCACCCGCGAGTCCACGGTGGGCTTCCAGACCAAGGAAG
GGATCCTCGATTTCAGAGAGATCCAGGCCTCTGCGATGAACGAGTTGAGGCGCATCTTCCGTCCCGAGTTCCTCAACCGT
ATCGATGAGATCGTGGTGTTCAAGAGCCTCAGCAGGGCGGATCTCGAACGGATATTGGGGCTCCTCCTGGAAGAGGTGTT
CCAGCGGGTGAGGGAGCAGGGGATGGAGATAGAGATCACGAAGCGCGCTCGGGAGTATCTCCTGGAAAAAGGGTATGATC
CTCGCTATGGAGCGCGACCCCTCAGGAGGACCATACAACGCGAGCTCGAAGACCCGCTCTCCATGGAGATCCTCAGGCAG
CGTTTCGTGCCGGGATCGTACATCCTGGTGACGGTGAGGAGCGGGAAGCTCGTGTTCCAGCAGAAACAGACCAAGAAACC
CCCTGAAAAGGTGACGGTGGAGACCCGGTAG

Protein sequence :
MFKDLTQRAQKILTVLAQDEAKRFHAEELEPEHIILAIIREGAGVAYRAIKRLKIAPEEIQVFVEKNLSKQRGSFILGDV
PLSSRSRRVLEYAAEEARHLDDEYIGTEHLMLGCARDGEGVFTRFLAQKGIDLEVLREAILEVKGSESVYNSSWGGKEEQ
EKRRGAFQSAAYRKNTPLLDEFSRDLTELAQTGKLDPVIGRERELRRIVQILARRTKNNPVLIGDPGVGKTAIVEALAQR
IVRGEVPEILEGKRILVLDLAALVAGTKYRGEFEERLKRVMREIVSVKNVVLFIDELHTIIGAGGAEGAIDASNMLKPAL
SRGEIQCIGATTLDEYRKYIEKDAALERRFQPVYVREPTIEETIQILEGIKTRYEDFHNVTYTRKAVEAAVVLSARYITE
RHLPDKAIDLLDEAGSRTHVQVLNRPQEIEELEKKIEQLNSEKIMLVNTQNYERAAAVRDQVNRLKMELERLKTAWKLEI
KRTQNIVDQEDIQEVVSDITGIPLVRIAQSESERLLHIEEELHRKVISQDEAIKVVASAIRRARTGLSSPNRPMGSFVFL
GPTGVGKTLLAKTLAEYLFGDTSALIRLDMSDFMEKHNVSRLVGAPPGYVGYEEGGLLTEKVRHRPYSVILFDEIEKAHP
DVFNILLQILEEGELQDNLGHRVSFRNAVLIMTSNAGAREITRESTVGFQTKEGILDFREIQASAMNELRRIFRPEFLNR
IDEIVVFKSLSRADLERILGLLLEEVFQRVREQGMEIEITKRAREYLLEKGYDPRYGARPLRRTIQRELEDPLSMEILRQ
RFVPGSYILVTVRSGKLVFQQKQTKKPPEKVTVETR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 7e-166 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB1 YP_003874452.1 chaperone ClpB VFG0079 Protein 0.0 52
clpB1 YP_003874452.1 chaperone ClpB VFG0080 Protein 2e-148 51