Gene Information

Name : STHERM_c10030 (STHERM_c10030)
Accession : YP_003874222.1
Strain : Spirochaeta thermophila DSM 6192
Genome accession: NC_014484
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1094461 - 1096014 bp
Length : 1554 bp
Strand : +
Note : GMP synthetase; glutamineamidotransferase; glutamine-hydrolyzing

DNA sequence :
ATGGAAAAGATCCTAGTCCTCGATTTCGGAGGTCAGACCTGCCAGCTCATCGCCAGGCGGATCCGTGAGATAGGGGTCTA
CAGCGAGGTCGTTCCCGGCGATACGCCGGTGGAATCCCTACCCCTTGAAGGCGTGAAGGGGATCATCCTCTCGGGCTCTC
CCTACTCGGTCTACGATGCGGAGGCGCCGAAGGTCGATCCGCGCGTCTCTTCCCTGGGTATCCCCATACTGGGGATATGC
TACGGGGTGCAGCAGCTCGCGCACCTTTTCGGGGGGAAGGTGGCCCCGCTCGATCACCGCGAGTACGGTCGGAGTAGACT
CTTCTTCACCGAAGCCTCGCCGCTCTTCGAGGGCGTCCCGGAAGGGTTCGTCTCGTGGATGAGCCACGGAGACACCATCG
TGGAGGTGCCCGAGGGATTTCGAGTGATCGCACGTTCGGAGCACAACCTGGTGGCCGGCATAACCCACGAGCGACTCCCG
CTCTACGGGATCCAGTTCCATCCGGAGGTGACCCACTGCGAGTACGGCCTCACCGTGCTCGAGAACTTCGCCGTACGTAT
CTGTGGGGCCCGGAAGACGTGGACCATGGCCTCGTACCTCGAGGATGTCCAGGGACTCCTCAGGACACAAGTGGGGGATG
ATCCTCTCCTCCTCCTCATTTCGGGAGGGGTGGACTCCACCGTGGTGGCCGCCCTCCTGCTCAAGACATTCCCACCCGAG
CAGGTCCATCTCCTCTACATCGATACCGGCCTCATGAGGAAGAACGAGACCGAGGAGGTGGAGGCCAATCTCCGAACCCT
TGGAGCCAGCAATCTCTATATCGTCCATGCCGAGGAGAGGTTCCTTTCGGCCCTCAAGGGGGTGGTGGATCCCGAGAAGA
AACGTCAGATTATCGGGGATGTGTTCATCCAGGTCCAGGAGGAGGAGCTTCGGCGTCGAAGGATCCCCGATCAGGCCTTC
CTCGCCCAGGGGACCCTCTACACCGATCTCATCGAATCTGGGAAAGGCGTGGGGAACAAGGCGAAGGTCATCAAATCGCA
TCACAATGTGCGATCCCCCCTCATCGAGCGGAAGCGGAAGGAAGGGAGAGTGATCGAGCCCCTCTCCATGCTCTACAAGG
ATGAGGTGCGCAGACTGGGGGCTCATCTCGGCGTACCCCGGGAGGTGCTCGAGCGCCACCCGTTTCCTGGACCCGGCCTC
GCGGTGAGGATACTCGGGGAGGTGACCAGGGAGAAGTGCGACATCCTCCGGGAAGCCGACGCGATTTTCATCGACGAGCT
GAAGAGGCGTCACCTGTACCAGGAGATATGGCAGGCCTTCTGTGTCCTTCTGCCGGTACGGACCGTGGGGGTCACAGGGG
ACGACCGCAACTACGGGTATGTGGTGGCCCTCCGTGCCGTCACGTCCAAGGACGGGATGACGGCCGACGCCTATCCCTTT
CCCACGGCGGACCTGTTGGAGATCGCTGCGCTCATCACGAACCGTGTCAAGGATGTAGGCCGGGTGGTCTACGATGTCTC
GAGCAAACCACCCGCCACCATAGAGTGGGAGTAG

Protein sequence :
MEKILVLDFGGQTCQLIARRIREIGVYSEVVPGDTPVESLPLEGVKGIILSGSPYSVYDAEAPKVDPRVSSLGIPILGIC
YGVQQLAHLFGGKVAPLDHREYGRSRLFFTEASPLFEGVPEGFVSWMSHGDTIVEVPEGFRVIARSEHNLVAGITHERLP
LYGIQFHPEVTHCEYGLTVLENFAVRICGARKTWTMASYLEDVQGLLRTQVGDDPLLLLISGGVDSTVVAALLLKTFPPE
QVHLLYIDTGLMRKNETEEVEANLRTLGASNLYIVHAEERFLSALKGVVDPEKKRQIIGDVFIQVQEEELRRRRIPDQAF
LAQGTLYTDLIESGKGVGNKAKVIKSHHNVRSPLIERKRKEGRVIEPLSMLYKDEVRRLGAHLGVPREVLERHPFPGPGL
AVRILGEVTREKCDILREADAIFIDELKRRHLYQEIWQAFCVLLPVRTVGVTGDDRNYGYVVALRAVTSKDGMTADAYPF
PTADLLEIAALITNRVKDVGRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-107 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-107 48
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-107 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-92 45