Gene Information

Name : PPE_04310 (PPE_04310)
Accession : YP_003872612.1
Strain : Paenibacillus polymyxa E681
Genome accession: NC_014483
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4686752 - 4689196 bp
Length : 2445 bp
Strand : -
Note : COGMatches:COG0542; PfamMatches:PF02861, PF00004, PF02151, PF07724; PrositeMatches:PS50151, PS00870, PS00871; go_process: protein metabolism (GO:0019538), go_fucntion: ATP binding (GO:0005524), go_process: nucleotide-excision repair (GO:0006289)

DNA sequence :
ATGATGTTTGGAAGATTTACGGAACGTGCACAGAAAGTGCTTGCTTTGGCTCAGGAAGAAGCTGTTCGATTGGGACACAA
CAACATTGGCACAGAACACATTTTGCTAGGTCTCATTCGTGAAGGTGAAGGAATAGCAGCAAAAGCCTTAATCGGTTTAG
GGCTGGGACTCGAAAAAATCCAGGATGAAGTGGAAACGCTGATTGGACGCGGTCAAGAGCAACCGACGAACATTGCCTAT
ACTCCACGCGCCAAAAAGGTCATCGAACTGTCTATGGATGAAGCCCGCAAACTGGGCCATACCTATGTAGGTACAGAACA
TATTTTGCTTGGTCTTATTCGTGAAGGCGAAGGCGTAGCAGCACGCGTACTGAACAACCTGGGCATCAGTCTGAACAAAG
CGCGTCAGCAAGTGCTTCAATTGCTCGGCAGCAGCGAGGCTGTTTCCAGCCATCACGGTGCTCCAGCTAATGTCAGCACG
CCAACTCTGGACAGTCTGGCACGCGATCTGACGGCATCTGCGAAGGAAAACAACCTGGACCCTGTTATTGGGCGTAGCAA
GGAAATTGAACGCGTAATCCAGGTGCTCAGCCGCCGTACAAAGAACAATCCGGTTCTGATTGGTGAGCCTGGGGTAGGTA
AAACGGCGATTGCCGAAGGTTTGGCCCAAAAAATCATAGCGAATGAGATTCCCGAAACGTTGCGTGACAAGCGCGTAATG
ACACTGGATATGGGTTCTGTGGTAGCAGGCACCAAGTATCGTGGTGAATTCGAGGATCGTTTGAAAAAAATTATGGACGA
GATTCGTCAAGCGGGTAATATCGTGTTGTTCATTGATGAGCTGCATACGCTGATTGGTGCTGGTGGAGCGGAAGGCGCAA
TTGATGCGTCCAACATCCTGAAACCTGCTCTGGCACGTGGCGAGCTGCAATGCATCGGTGCGACCACGCTGGATGAATAC
CGCAAATATATTGAGAAAGATGCTGCTTTGGAACGTCGTTTTCAACCCATTACAGTGGATCAACCTTCTCCAGAAGAGGC
GATTCAAATCTTGTATGGTCTGCGTGACCGTTACGAAGCGCATCACCGTGTAAAGATCACAGATGAGGCTATTGAAGCGG
CTGTAAAATTGTCAGATCGTTATATCACCGACCGCTTCCTGCCAGATAAGGCAATTGACCTTATTGATGAAGCGGGCTCC
AAAGTAAGGCTGAATTCTTACACTGTACCGCCAAACCTGAAACAGCTGGAAAACCGTCTGGAAGATATCCGTAAGGAAAA
GGATTCAGCGGTACAAAGCCAGGAGTTTGAAAAAGCGGCAGCGCTGCGTGATACAGAGCAAAAAATCCGTGAAGAGCTAG
ACGTGACGAAAAACCAATGGAAAGAACAACAGGGTCGTACAGATTCTGAAGTTACACCAGAGGATATCGCTCAGGTCGTT
GCAATCTGGACAGGTGTTCCAGTCAGCAAGCTGAAAGAGGAAGAAACACACCGCTTGTTGAATATGGAAGAGTTGCTGCA
TGAGCGGGTAATTGGACAGGATGAAGCAGTTAAGGCAGTAAGCCGGGCGATTCGCCGGGCACGTGCCGGATTGAAAGATC
CGAAACGTCCAATGGGTTCCTTTATTTTCCTCGGTCCAACTGGGGTGGGTAAAACAGAGTTGGCACGCGCCTTGGCTGAA
TCCATGTTTGGAGATGAAAATGCGGTTATCCGTATTGATATGTCTGAATATATGGAGAAACACTCCACGTCCCGTCTGGT
AGGAGCGCCTCCAGGGTATGTTGGATATGAGGAAGGCGGTCAACTGACCGAGAAGGTACGTCGTAAGCCTTACTCTGTTG
TATTGCTGGATGAAATTGAAAAAGCACACCCAGAAGTATTCAATATTCTTCTGCAAGTACTGGAAGATGGTCGTCTGACA
GATTCCAAAGGTCGTGTCGTTGATTTCCGTAATACACTCATCATCCTAACATCAAATGTTGGTGCACAGGCGATTAAACG
TAACTCCACGCTTGGTTTTACAGCTGTAGTGGACGCTGGGGCGGATTACGATAATATGAAGGGCAAAGTGATGGATGAAC
TGAAGAAAAGCTTCCGTCCTGAGTTCTTGAACCGGATTGATGAAATTATCGTTTTCCATTCTCTCGAAGAAAAACATATT
GCCGAAATTGTGTCACTCATGTCTGAGGAGCTACGTAAGCGCCTGAACGAGTATGAGGTGGACTTCGAGTTGACAGACAA
CGCTAAAAAATTCCTTGCCAAGGAAGGCTTTGATCCAGCGTATGGTGCGCGTCCATTGCGTCGTGCAATCCAGAAGCATA
TTGAAGATCGCCTGTCCGAGGAACTGTTGACTGGCAACATTACTAAGGGTGACTCTCTCTTCATTGATGAGGAGAATGGT
GCATTGACTGTAACGAAAAAGGATAATGTATCTGCCAAGTCCTAA

Protein sequence :
MMFGRFTERAQKVLALAQEEAVRLGHNNIGTEHILLGLIREGEGIAAKALIGLGLGLEKIQDEVETLIGRGQEQPTNIAY
TPRAKKVIELSMDEARKLGHTYVGTEHILLGLIREGEGVAARVLNNLGISLNKARQQVLQLLGSSEAVSSHHGAPANVST
PTLDSLARDLTASAKENNLDPVIGRSKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIAEGLAQKIIANEIPETLRDKRVM
TLDMGSVVAGTKYRGEFEDRLKKIMDEIRQAGNIVLFIDELHTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKYIEKDAALERRFQPITVDQPSPEEAIQILYGLRDRYEAHHRVKITDEAIEAAVKLSDRYITDRFLPDKAIDLIDEAGS
KVRLNSYTVPPNLKQLENRLEDIRKEKDSAVQSQEFEKAAALRDTEQKIREELDVTKNQWKEQQGRTDSEVTPEDIAQVV
AIWTGVPVSKLKEEETHRLLNMEELLHERVIGQDEAVKAVSRAIRRARAGLKDPKRPMGSFIFLGPTGVGKTELARALAE
SMFGDENAVIRIDMSEYMEKHSTSRLVGAPPGYVGYEEGGQLTEKVRRKPYSVVLLDEIEKAHPEVFNILLQVLEDGRLT
DSKGRVVDFRNTLIILTSNVGAQAIKRNSTLGFTAVVDAGADYDNMKGKVMDELKKSFRPEFLNRIDEIIVFHSLEEKHI
AEIVSLMSEELRKRLNEYEVDFELTDNAKKFLAKEGFDPAYGARPLRRAIQKHIEDRLSEELLTGNITKGDSLFIDEENG
ALTVTKKDNVSAKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PPE_04310 YP_003872612.1 Negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 77
PPE_04310 YP_003872612.1 Negative regulator of genetic competence clpC/mecB VFG0080 Protein 6e-155 52
PPE_04310 YP_003872612.1 Negative regulator of genetic competence clpC/mecB VFG2084 Protein 3e-97 41