Gene Information

Name : PPE_02107 (PPE_02107)
Accession : YP_003870481.1
Strain : Paenibacillus polymyxa E681
Genome accession: NC_014483
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2245015 - 2246145 bp
Length : 1131 bp
Strand : +
Note : COGMatches:COG0626; PfamMatches:PF01053; PrositeMatches:PS00868; go_process: amino acid metabolism (GO:0006520)

DNA sequence :
ATGAAACGCAAAACAAAACTGATTCACGGTGGGCTTCCTACCGATCCCCATACAGGCGCGGTTAACGTTCCTATTTATCA
GGTAAGCACTTATGAGCAAGAGGAAATTGGCGTCCATAAGGGATACGAATATTCGCGTACAGGCAATCCGACTCGGTTTG
CTCTGGAGGAACTGATCAAGGATCTGGAGGAAGGAAAGCGTGGTTTTGCTTTCGGTTCGGGTATGGCAGCAATTCATGCA
GTATTTTCACTGTTTAATACAGGGGATCATATTTTGCTGACCGATGATGTATACGGAGGCACCTACCGTATTGTAAGCAA
AGTCCTCAGCCGTATCGGAATTGAGTCCACATTTGTGGATACGACTGACCTGGAAGCCATCTCCAAAGCAATTCGTCCGA
ATACAAAGGCATTGTATGTCGAAACGCCAACGAACCCGCTTTTGAAGGTTACGGATATCCGCGCTGTTTCGGAGCTTGTA
AAAAAACATGATCTTTTACTGATCGTCGACAACACGTTTGCTACCCCTTATTGGCAGACGCCAATTACACTTGGGGCTGA
TATCGTCATTCACTCTGCTACCAAGTATTTGGGCGGCCATAGCGATGTTGTAGCCGGTCTGGCTGTTGTGAACAGTGACG
AGCTGGGAGAACAACTTCATTTTCTGCAAAACGCCATTGGTGCTATTCTCGGCCCGCAAGATTCTTGGTTATTGATCCGA
GGTATTAAAACATTGGGTCTGCGTATGGAAGCGATTGAGCAAAACGCGAAGGAAATTGCAGCCTTTTTGGAAAAACATCC
AAAGGTTAGCAAAGTGTACTATCCTGGACTGGAAAGCCATGCACAGCATGAACTGTCCAAAATCCAAGCCGAAGGCTTTG
GCGGCATCATTTCCTTTGATGTAGGTAGCGACGCTAACGCGGTTGCACTTCTGAAAAAGGTGAAATATTTTACACTGGCT
GAAAGCTTGGGAGCGGTTGAAAGTCTGATTAGTGTTCCGGCACGTATGACGCACGCCTCTATTCCAGTAGAACGTCGTGC
AGAGCTCGGTATTACCGAAGGTTTGGTGCGTATTTCGGTTGGGATTGAAGATCTCGAAGATTTGATCGAAGATTTGCAGG
CAGCATTGTAA

Protein sequence :
MKRKTKLIHGGLPTDPHTGAVNVPIYQVSTYEQEEIGVHKGYEYSRTGNPTRFALEELIKDLEEGKRGFAFGSGMAAIHA
VFSLFNTGDHILLTDDVYGGTYRIVSKVLSRIGIESTFVDTTDLEAISKAIRPNTKALYVETPTNPLLKVTDIRAVSELV
KKHDLLLIVDNTFATPYWQTPITLGADIVIHSATKYLGGHSDVVAGLAVVNSDELGEQLHFLQNAIGAILGPQDSWLLIR
GIKTLGLRMEAIEQNAKEIAAFLEKHPKVSKVYYPGLESHAQHELSKIQAEGFGGIISFDVGSDANAVALLKKVKYFTLA
ESLGAVESLISVPARMTHASIPVERRAELGITEGLVRISVGIEDLEDLIEDLQAAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-114 62
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-112 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-79 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PPE_02107 YP_003870481.1 cystathionine gamma-synthase BAC0207 Protein 3e-66 42