Gene Information

Name : dhbE (BSUW23_15550)
Accession : YP_003867456.1
Strain : Bacillus subtilis W23
Genome accession: NC_014479
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 3072073 - 3073692 bp
Length : 1620 bp
Strand : -
Note : -

DNA sequence : 
ATGCTGAATGGATTTACTCCTTGGCCTGAAGAGTTAGCTGAGACATATCGGAAGAACGGCTGCTGGGCCGGCGAGACGTT
TGGAGATTTGTTAAGGGACCGGGCTGCTAAACATGGCGATCGCATTGCCATTACCTGCGGAAACACCCATTGGAGCTATC
AAGAGCTTGATACGAGGGCTGATCGTCTGGCTGCTGGATTTCAGAAGCTCGGCATTAAACAGATGGATCGTGTCGTGGTG
CAGCTGCCGAATATCGCAGAGTTTTTTGAAGTCATTTTCGCGCTCTTCCGTCTGGGGGCGCTCCCGGTCTTTGCACTGCC
TTCTCATCGAAGCAGTGAAATTACATATTTTTGCGAGTTTGCTGAAGCGGCTGCTTATATTATTCCCGACTCTTATTCCG
GTTTTGACTACCGTTCACTTGCCAGACAGGTTCAAAGCAAACTGCCGACTTTGAAACACGTCATTGTCTCAGGGAAGGCA
GAAGAATTTTTGCCGCTGGAGGATTTGCATACAGAACCTGTAAAACTGCCTGAAGTCAAATCTTCTGATGTGGCGTTCCT
TCAGCTTTCTGGAGGAAGCACCGGCTTATCAAAACTGATCCCGCGGACACACGATGACTACATATACAGTCTGCGGCGGA
GTGCAGAAGTTTGCTGGCTCGACCACAGCACGGTGTACTTGGCAGCATTGCCGATGGCGCACAATTACCCGCTGAGCTCA
CCTGGGGTTCTCGGCGTGTTATACGCCGGAGGAAGAGTGGTATTATCTCCTTCACCAAGTCCTGATGACGCATTTCCTTT
GATTGAACGGGAGCAAGTCACGATTACCGCTCTTGTTCCGCCCCTTGCAATGGTATGGATGGATGCGGCATCCTCACGCG
ATGACGATCTATCCAGCCTTCAAGTGCTGCAGGTCGGCGGCGCCAAGTTCAGTGCTGAAGCTGCGAGCAAGGTTAAAGCT
GTTTTCGGCTGCACGCTGCAGCAGGTGTTCGGAATGGCAGAGGGTCTCGTCAATTATACAAGACTGGATGACCCTGAGGA
GGTCATTATCAACACCCAAGGAAAACCGATGTCCCCATATGATGAAGTACGTGTTTGGGATGACCAGGATCGTGACGTAA
AACCTGGTGAAACAGGGCATCTGCTGACACGGGGGCCGTACACGATTCGGGGTTACTATAAAGCAGAAGAGCATAATGCT
GCTTCTTTTACTGAGGACGGTTTTTACCGCACGGGTGATATCGTCAGGCTGACATCAGACGGCTATATTGTCGTTGAAGG
CAGGGCGAAGGATCAAATTAATCGCGGGGGAGAAAAAGTGGCGGCTGAAGAGGTAGAAAATCATCTTCTGGCTCATCCGG
CTGTCCATGATGCCGCAATGGTCTCAATGCCTGACCAATTTCTTGGCGAAAGATCTTGTGTGTTCATTATTCCCCGGATT
GAAGCCCCGAAAGCCGCAGAGCTCAAAGCTTTTTTGAGAGGGCGCGGACTGGCGGCATACAAAATCCCCGATCGCATTGA
ATTTGTCGAATCCTTTCCGCAGACAGGGGTAGGGAAAGTCAGCAAAAAAGCGCTTCGTGAAGCCATTACCGAGAAGCTTC
TTGCAGGATCAAAAAAATAA

Protein sequence : 
MLNGFTPWPEELAETYRKNGCWAGETFGDLLRDRAAKHGDRIAITCGNTHWSYQELDTRADRLAAGFQKLGIKQMDRVVV
QLPNIAEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAAAYIIPDSYSGFDYRSLARQVQSKLPTLKHVIVSGKA
EEFLPLEDLHTEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLRRSAEVCWLDHSTVYLAALPMAHNYPLSS
PGVLGVLYAGGRVVLSPSPSPDDAFPLIEREQVTITALVPPLAMVWMDAASSRDDDLSSLQVLQVGGAKFSAEAASKVKA
VFGCTLQQVFGMAEGLVNYTRLDDPEEVIINTQGKPMSPYDEVRVWDDQDRDVKPGETGHLLTRGPYTIRGYYKAEEHNA
ASFTEDGFYRTGDIVRLTSDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGERSCVFIIPRI
EAPKAAELKAFLRGRGLAAYKIPDRIEFVESFPQTGVGKVSKKALREAITEKLLAGSKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-115 50
ybtE CAA21394.1 - Virulence HPI Protein 2e-115 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-116 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-115 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-116 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-115 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-115 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-115 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-115 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_003867456.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-135 55
dhbE YP_003867456.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 8e-111 49
dhbE YP_003867456.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 4e-111 46