Gene Information

Name : PB2503_12389 (PB2503_12389)
Accession : YP_003855662.1
Strain : Parvularcula bermudensis HTCC2503
Genome accession: NC_014414
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 2524656 - 2526107 bp
Length : 1452 bp
Strand : -
Note : -

DNA sequence :
ATGAATCAAACCGTAAAGACAGGCGATTGCTGCTCCGTCAATAAAAACGGCGACGACAGCTATGACCTCATCGTCATAGG
TGCTGGCTCGGCCGGGTTTTCGGCTTCGATTAGCGCGGCCGAGGCCGGCAGGCGCGTGGCCATGGTTGGGCATGGCACCA
TCGGCGGCACCTGCGTCAATGTCGGCTGCGTGCCGTCCAAGGCGATGATACGGGCCGGTGAAGCGGTGCATGCTGGTACA
GCGGCGGCACGGTTTCCGGGCATTGAGCCCTGTGCGCACAGCGTGGACTGGTCGGCGGTCGTCAAGGGCACGGCCGATCT
GGTCGACGAGATGCGCCAGAAAAAATACATCGACCTGCTGCCTTCCTATGAGTATGTCACCTATATCGAGGAAGGTGCCG
CACGCCTGGTCGAAGGCGGCATCGAAGTCGGCGGGCGGATCATCGCTGCACCGAAGGTTCTGATCGCCACCGGCTCGCGC
CCTTTCTTGCCGGAAATTGACGGGATCGAGACCGTGGAGGCGCTCGATTCCTGGGACCTTCTCAGCCTGCCCGATCAGCC
CGAAAGCATCCTGGTACTGGGCGGCGGCTATATTGGCTGTGAACTGGCGCAGATGGCGTCGCGGCTGGGCGTCAAGGTTA
CACTGGTCACGCGTTCGCGCCTTCTGCCCGGCGTGGAACCGGAAGTGGCCAAGGCGTTGACCGACGCGTTGAAGGCTGAG
GGTGTCGCGGTCGAGACCGGCCTGTCCTACCGATCGGTGAGACGGAGTGACGGCGGCGTCACGCTGACAATCGAACGGGG
TGGAAAGCCCGTGACCCTCTCCGCGCAGCGGCTTGTGGCCACCACTGGCCGGGTGGCCAATTCCGAAGACCTCGGCTTGC
GCGAGTTCGGCATCGAGACCGATGCGCGTGGATCGATCAAGGTCGGAGCCGACATGGCCACAACGCGGCCTGGCGTCTGG
GCAGCGGGTGATGTCACCGATCGCGACCAGTTCGTCTACATGGCCGCTTATGGGGCCAAGGTGGCGGTCAACAATGCGCT
CGGGCTTCAGGATTTGCGCTATGACAATGCGGCCATGCCCTGGGTCGTGTTCACCGATCCGCAGGTCGCCGGCGTCGGCC
TTTCCGAGGTGCAGGCGAAGGCAGCCGGTCATGACGTCAAGACCAGCGTGCTGACGCTGGACCACGTGGCACGCGCCGCC
GCCGCCCGCGATACCCGCGGCGTCATCAAGCTGGTCGCGGATGCGAAGACCGACCGCCTCCTGGGCGGACAGATCGCGGC
GCCCGAAGGGTCTGATGCGATTCAGACGCTGGCTATGGCGTTGAAGTTCGGCATGACGAGCAAGGCGCTTGGCGAGACAA
TTTTTCCATACCTGACAACTGTTGAAGGGTTAAAATTGGCGGCACAGACGTTCGACAAGGACGTGGCGAAGCTTTCATGC
TGCGCAGGCTGA

Protein sequence :
MNQTVKTGDCCSVNKNGDDSYDLIVIGAGSAGFSASISAAEAGRRVAMVGHGTIGGTCVNVGCVPSKAMIRAGEAVHAGT
AAARFPGIEPCAHSVDWSAVVKGTADLVDEMRQKKYIDLLPSYEYVTYIEEGAARLVEGGIEVGGRIIAAPKVLIATGSR
PFLPEIDGIETVEALDSWDLLSLPDQPESILVLGGGYIGCELAQMASRLGVKVTLVTRSRLLPGVEPEVAKALTDALKAE
GVAVETGLSYRSVRRSDGGVTLTIERGGKPVTLSAQRLVATTGRVANSEDLGLREFGIETDARGSIKVGADMATTRPGVW
AAGDVTDRDQFVYMAAYGAKVAVNNALGLQDLRYDNAAMPWVVFTDPQVAGVGLSEVQAKAAGHDVKTSVLTLDHVARAA
AARDTRGVIKLVADAKTDRLLGGQIAAPEGSDAIQTLAMALKFGMTSKALGETIFPYLTTVEGLKLAAQTFDKDVAKLSC
CAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-62 43
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 5e-83 42
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 6e-83 42
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-63 42
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-63 42
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-63 42
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 7e-60 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 6e-60 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 6e-60 41
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 9e-61 41
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 9e-61 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PB2503_12389 YP_003855662.1 mercuric reductase BAC0224 Protein 3e-82 44
PB2503_12389 YP_003855662.1 mercuric reductase BAC0651 Protein 3e-83 42
PB2503_12389 YP_003855662.1 mercuric reductase BAC0652 Protein 2e-62 41
PB2503_12389 YP_003855662.1 mercuric reductase BAC0653 Protein 6e-61 41