Gene Information

Name : Tthe_0771 (Tthe_0771)
Accession : YP_003851409.1
Strain : Thermoanaerobacterium thermosaccharolyticum DSM 571
Genome accession: NC_014410
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 794264 - 796015 bp
Length : 1752 bp
Strand : +
Note : KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGCGTAGAACTAAGATAATATGCACAATAGGTCCTGCAAGTGAAAAATATGAAATACTGAGAGAACTAATTGAAAGTGG
CCTAAATATTTGCAGATTAAATTTTTCTCATGGCGATCATGAAGAACATGGAAGCAGAATAGACAATATAAAAAAGATTA
GAGAAGAGCTTCAGCTGCCGATTGCTATTATGCTTGATACAAAGGGACCGGAAATAAGAACTGGGAAATTTAAAAATGGA
GTTGCTGAGCTAAAAGAGGGACAGACGTTTACGATAACCTCTAGGGATATTGAAGGCGATGATACTATTTGTTCGGTGAC
ATATAAAGGACTTCCTCAAGATGTTGAAAGAGGTTCTCGCATATTGATCGATGATGGGTTGGTATCTTTAAAAGTCAATG
ATGTAAAAGGCGAAGACATAATATGTACAGTTGAGAATTCTGGAACGATTGGAGATCATAAAGGTGTAAATGTACCTGGA
ACCAAGTTGAACTTACCTGCTATCACGCAAAAAGACGTAGACGACATAGAGTTTGGAATAAAAAAGGGCATTGATATGAT
AGCCGCCTCTTTCGTGAGAAAAGCAGCAGATGTAATTGCTATAAGAAGGCTATTAGAAGATAACGATGCAGGTCACATAC
TCATCATCTCTAAGATAGAAAATCGTGAGGGTGTAGAAAATATAGACGAGATTATAAAAGTTTCAGATGGCATAATGGTT
GCCCGTGGAGATTTAGGTGTAGAAATACCAATAGAAGAAATACCAATAGTTCAAAAAAGAATAATTGAGAAGTGCAATAA
AGCAGGTAAGCCAGTTGTCACAGCCACTCAAATGCTTGATTCTATGATAAGAAATCCAAGACCTACAAGAGCAGAAGTTA
CAGATGTAGCAAATGCTATATTGGATGGTACGGACGCTATAATGTTATCTGGCGAAACGGCTCAAGGGAAATACCCTGTA
GAAGCTTTTAAGACGATGTCAAAGATAGCTGAAAAAATAGAGACGTATATAAATTACAAAGAAAATTTGGACAAGAATGT
GGACTACAATATTTCTATGACAAATGCTATAAGCCATGCAACATGTACAACTGCAAGAGATATAGGTGCAACTGCTATTA
TTACATCTACAATATCAGGTTACACAGCAAGAATGGTATCTAAATACAGACCGTCAGCTCCTATAATAGCGGTGACACCA
AACAAAGATGTGGCGAGAAGGCTTAGCATTGTATGGGGTGTACATCCTTTGATATCACAAGAAGTTAACTCTACAGATGA
AATGATAGAAGTTTCGGTAAATACCGCTCTTAACGAAGGTCTAATTCGGAATGGTGACATTGTTGTAATCTCTGCAGGAA
TACCAGTTGCTACGACAGGTACAACAAATATGTTAAAGGTTCATATAGTCGGCGATGTGATAGTAAAAGGAACGGGTATA
GGTACAAAATCAATAAGTGGTGTTGTCTCTATCATTCGCGATCCATATAAAGATAAGGATAAATTTAGAGAAGGAGATAT
TATCGTTGCACAAAAAACAGAAAGAGATTATATGCCTATAATAGAGAAGGCGTCGGCGATAATAACTGAAGAAGGAGGCC
TTACATCACATGCAGCAATTGTAGGGCTCAATTATGGGATACCTGTAATTGTAGGATGTGAAGGAGTTACTGCAAAACTG
AAAGACGGCATGACTGTTACGCTTGATGCAGCGAGAGGCTTAGTGTATAAGGGAATAGTAAATATAAAATAG

Protein sequence :
MRRTKIICTIGPASEKYEILRELIESGLNICRLNFSHGDHEEHGSRIDNIKKIREELQLPIAIMLDTKGPEIRTGKFKNG
VAELKEGQTFTITSRDIEGDDTICSVTYKGLPQDVERGSRILIDDGLVSLKVNDVKGEDIICTVENSGTIGDHKGVNVPG
TKLNLPAITQKDVDDIEFGIKKGIDMIAASFVRKAADVIAIRRLLEDNDAGHILIISKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPIEEIPIVQKRIIEKCNKAGKPVVTATQMLDSMIRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPV
EAFKTMSKIAEKIETYINYKENLDKNVDYNISMTNAISHATCTTARDIGATAIITSTISGYTARMVSKYRPSAPIIAVTP
NKDVARRLSIVWGVHPLISQEVNSTDEMIEVSVNTALNEGLIRNGDIVVISAGIPVATTGTTNMLKVHIVGDVIVKGTGI
GTKSISGVVSIIRDPYKDKDKFREGDIIVAQKTERDYMPIIEKASAIITEEGGLTSHAAIVGLNYGIPVIVGCEGVTAKL
KDGMTVTLDAARGLVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-95 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-95 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-95 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-95 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tthe_0771 YP_003851409.1 pyruvate kinase VFG0479 Protein 6e-96 49