Gene Information

Name : Tthe_0722 (Tthe_0722)
Accession : YP_003851361.1
Strain : Thermoanaerobacterium thermosaccharolyticum DSM 571
Genome accession: NC_014410
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 742787 - 743923 bp
Length : 1137 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: gwc:GWCH70_2474 cystathionine gamma-synthase

DNA sequence :
ATGAGAAAGGAGACAAAATTAATTCATGGTGGTATATTTGGTGACGAAAAAACAGGTGCAGTATCAACACCTATATACCA
AACATCGACGTTTAAACAGGATGCCGTAGGAAAAGATAGGGGTTATGAATATTCAAGAACAGGTAATCCAACACGAGAAT
CATTAGAAAAGCTTATTAATGATCTAGAGGGTGGAAAGGGTGGTTTTGCCTTTGCATCTGGCATGGCAGCAATATCGACA
GTTTTGATGCTTTTTAATGCTGGTGACGAGGTAATAGTTTCAAATAATGTTTATGGAGGAACATTCAGGGTACTTGAGAA
AGTTTTTAAAAGGCTTGGCATAGTTTCAAAATTTGTAGACACGTCTTTAAAAGATGATGTTGTAAATAGTATAACAAAAA
ATACAAAGGCAATATTTTATGAAACACCTACAAATCCTCTTATGACAATTACAAATATCAGAGAAATTTCAAGAATAGCT
AAAGAATATAGCATACTTTCGATAGTTGATAATACTTTTATGACACCATATTTCCAAAGACCCATTGAATTAGGTGCAGA
CATAGTTGTTCATAGTGCAACAAAATACCTTGGAGGCCATAGCGATGTTGTAGCAGGCCTTGTCGTTGTTAATAGTGAAG
AATTAGCTCATAAAATTCATTTTCTGCAAAATGCAGTTGGTGGCATTTTAGGACCACAGGATTCTTACCTTGTGATTAGG
GGAATAAAAACACTTAGCGTTAGAATGGAAAGACATGAGAAAAATGCCAAAGAAATTGCAAATTGGCTTTTGGAACAACC
TGAAGTTGAAAAAGTTTATTATCCTGGTTTACATACACATCCAGGATACGATATTGCAAAAGAGCAGATGGATGGCTTTG
GAGGCGTGATTTCATTTGAGTTAAAAAACAAAGATATGGCATTAAAATTATTAAACAATGTAAAACTTATTACACTTGCG
GAAAGCCTAGGCGGATATGAAAGCCTAATTTCATATCCAGCAAAAATGACACATGCGTCTATACCAGAGGAACAGAGATT
GAAGCTTGGCATAACCGATAAGTTAGTAAGACTATCAGTTGGACTTGAGAATTATCTGGATTTAATTGATGATTTAAAAA
ATGCAATAAGGAGTTGA

Protein sequence :
MRKETKLIHGGIFGDEKTGAVSTPIYQTSTFKQDAVGKDRGYEYSRTGNPTRESLEKLINDLEGGKGGFAFASGMAAIST
VLMLFNAGDEVIVSNNVYGGTFRVLEKVFKRLGIVSKFVDTSLKDDVVNSITKNTKAIFYETPTNPLMTITNIREISRIA
KEYSILSIVDNTFMTPYFQRPIELGADIVVHSATKYLGGHSDVVAGLVVVNSEELAHKIHFLQNAVGGILGPQDSYLVIR
GIKTLSVRMERHEKNAKEIANWLLEQPEVEKVYYPGLHTHPGYDIAKEQMDGFGGVISFELKNKDMALKLLNNVKLITLA
ESLGGYESLISYPAKMTHASIPEEQRLKLGITDKLVRLSVGLENYLDLIDDLKNAIRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-103 58
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-101 57
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-71 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tthe_0722 YP_003851361.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 8e-70 44