Gene Information

Name : Tthe_0400 (Tthe_0400)
Accession : YP_003851053.1
Strain : Thermoanaerobacterium thermosaccharolyticum DSM 571
Genome accession: NC_014410
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 395455 - 397887 bp
Length : 2433 bp
Strand : +
Note : KEGG: tte:TTE2327 ATPase with chaperone activity, ATP-binding subunit; PFAM: ATPase AAA; ATPase AAA central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: ATPase AAA

DNA sequence :
ATGGCAATGTTTGGAAGATTTTCAGAGAAGGCACAGAAAGTGCTTTATCAGGCACAAGAGGAGGCACGTTCTCTCTATCA
CAATTATGTGGGAACAGAGCACATTCTTTTAGGTCTTATTAAAGAAGAAGATGGAATAGCATCGAGAGTTCTTAAAAATC
TCGGTGTAACGTATGATGATATAAGGGCAAAGGTAGAGACTTTGATTGGAATGGGCAATGTACCAGGAGATGTTGTGGGA
TATACTCCTAGAGCAAAGAGGGTTTTAGAGCTTAGTTTTGCTGAGGCCAGGAGATTTAATACGAATTATATTGGTACAGA
GCACATTTTATTAGGGTTAATAAGAGAAGGCGAAGGTGTAGCAGTAAGGATATTGATGGAGTTAGGTGTGGATTTTAACA
GAGTTAGAGAAGAGATAGTAAAGATGGTCAGTGAAGAACCTTCTGGTGCCGCAAATAAGGCACAAAGGGCTAAAAATACT
AATACACCTAATTTAAACCAGTTTGGAAGGGATCTAACGGATCTCGCTAGAGAAGGGAAGTTGGATCCAGTTATAGGGCG
TGAAAAAGAAATAGAAAGAGTAATACAGATATTAAGCAGAAGAACTAAAAATAACCCATGTCTTATAGGAGAGCCTGGAG
TTGGAAAAACAGCAATTGCTGAAGGATTGGCGGAAGCAATTGAAAGCGGTACAATACCAGAAATCCTTAAAGGTAAACGT
GTTGTAACTTTGGATATGGCTTCAATGGTTGCAGGCACAAAATATAGAGGAGAATTTGAGGATAGGCTAAAAAATGTTTT
AAATGAAGTCATAAAGGCAGGAAATGTCATACTGTTCATAGATGAGTTACACACAATAATAGGAGCTGGTGCTGCTGAGG
GCGCAATAGATGCATCCAATATTTTAAAACCTGCCCTTGCAAGAGGAGAAATACAAGTAATAGGTGCGACGACTATAGAT
GAGTATCGGAAATACATTGAGAAAGACCCAGCGCTCGAAAGAAGATTTCAACCTATAATGGTTGAAGAGCCGTCTGTAGA
AGAAACGATTGAAATATTAAAAGGGCTTAGAGATAAATATGAGGCACACCACAGAGTAAAAATTACGGATGAAGCTATTG
AGGCTGCTGCAAAACTTTCACACAGGTATATAACAGATAGATATCTGCCTGACAAGGCTATAGATCTTATAGATGAAGCT
GCATCAAGGGTAAGATTAAAAACAGTTACAGCTCCACCAGAGATAAAAGAGTTAGAAGAAAAATTAAATATGTTGAATAA
GGATAAAGAAGAGGCAATTAGAACGCAAGAGTACGAAAAGGCTGCTAAAATAAGGGATGAAGAGCAAAAGATAAAAGAAC
AGTTGGAGAATTTAAAATCAAAGTGGCAGCAGAATTCATTGGTAAAAGATAAAAGCGTCGGTGCTGAGGAGATTTCTCAG
ATTGTATCACTGTGGACTGGAATTCCAACACAAAAATTGGCTCAAGAAGAGTCAGAGAGGCTTCTGCATTTAGAGGAGAT
CCTACACAAACGTGTAATAGGACAGGATGAAGCAGTTGACGCTGTAGCAAGAGCAATAAGGAGGGCAAGAGTTGGATTAA
AAGATCCTAGAAGACCTATCGGATCGTTCATATTCTTGGGACCAACTGGTGTTGGCAAGACAGAGCTTAGCAAAGCATTA
GCCGAAGCCATGTTTGGCGATGAGTCAGCAATAGTTAGAATAGATATGTCAGAATATATGGAAAAATTCTCTGTTTCAAG
GCTTATTGGCTCACCTCCTGGATATGTAGGATATGAAGAAGGCGGAGAACTTACAGAGAAAATAAGAAGGAAACCATATT
CTGTGATTCTCTTTGATGAGATTGAAAAGGCGCATCCTGATGTCTTCAATATACTTCTGCAGATTTTAGACGATGGAAGG
CTAACGGATTCAAAAGGCAGGACAGTAGACTTTAAGAATACGCTTATAATAATGACTTCTAATGTTGGTGCACAGCTTAT
AAAGAAGCAGACAACTTTAGGATTTATGCCTGAAGGCGAAGAAAATAAGGCATCATACGAAAAGATGAAAGAAAACATCT
TAGATGAGCTCAAAAAGTCATTTAGGCCTGAGTTTCTAAACAGGATAGATGATATTATCGTATTCCGTCAATTGACACAG
GACGACATAAGAAAAATTACTGATTTGATGATAGCTGATTTAAATAAGAGACTGAAGGACAATAATATTAGCCTTGAATT
TACAGATGATGCTAAAGAGGAGCTTTTAAAAGAAGGCTATGATGTAACGTATGGTGCAAGACCTTTAAGAAGGGCTATAC
AAAAAGTTGTTGAAAGTGAGCTTTCAGAATTGATGTTGAAAGGTGAAGTAAAATCCGGTGATAAAATTTTAGTGAAGCTG
AAAGACGGAAAATTTGATTTTACTAAAGTGTAA

Protein sequence :
MAMFGRFSEKAQKVLYQAQEEARSLYHNYVGTEHILLGLIKEEDGIASRVLKNLGVTYDDIRAKVETLIGMGNVPGDVVG
YTPRAKRVLELSFAEARRFNTNYIGTEHILLGLIREGEGVAVRILMELGVDFNRVREEIVKMVSEEPSGAANKAQRAKNT
NTPNLNQFGRDLTDLAREGKLDPVIGREKEIERVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAEAIESGTIPEILKGKR
VVTLDMASMVAGTKYRGEFEDRLKNVLNEVIKAGNVILFIDELHTIIGAGAAEGAIDASNILKPALARGEIQVIGATTID
EYRKYIEKDPALERRFQPIMVEEPSVEETIEILKGLRDKYEAHHRVKITDEAIEAAAKLSHRYITDRYLPDKAIDLIDEA
ASRVRLKTVTAPPEIKELEEKLNMLNKDKEEAIRTQEYEKAAKIRDEEQKIKEQLENLKSKWQQNSLVKDKSVGAEEISQ
IVSLWTGIPTQKLAQEESERLLHLEEILHKRVIGQDEAVDAVARAIRRARVGLKDPRRPIGSFIFLGPTGVGKTELSKAL
AEAMFGDESAIVRIDMSEYMEKFSVSRLIGSPPGYVGYEEGGELTEKIRRKPYSVILFDEIEKAHPDVFNILLQILDDGR
LTDSKGRTVDFKNTLIIMTSNVGAQLIKKQTTLGFMPEGEENKASYEKMKENILDELKKSFRPEFLNRIDDIIVFRQLTQ
DDIRKITDLMIADLNKRLKDNNISLEFTDDAKEELLKEGYDVTYGARPLRRAIQKVVESELSELMLKGEVKSGDKILVKL
KDGKFDFTKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-95 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tthe_0400 YP_003851053.1 ATPase AAA VFG0079 Protein 0.0 62
Tthe_0400 YP_003851053.1 ATPase AAA VFG0080 Protein 3e-140 51