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Name : Tthe_0219 (Tthe_0219) Accession : YP_003850878.1 Strain : Thermoanaerobacterium thermosaccharolyticum DSM 571 Genome accession: NC_014410 Putative virulence/resistance : Resistance Product : D-alanine/D-alanine ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : - Position : 215397 - 216482 bp Length : 1086 bp Strand : + Note : KEGG: tpd:Teth39_0187 D-alanyl-alanine synthetase A; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein DNA sequence : ATGGAAAAGCTAAAAGTGGCTGTTTTGTTTGGGGGACAATCTGGAGAGCATGAAGTGTCAAGGGTTTCAGCGACTTCGAT AATAAATAACATTGATAGAGATAAATATGATGTATATATGGTAGGCATAACTAAGAAGGGCGAATGGTATTTGTACAACG GAGATATTGAGAAAATAGCTACAGGCGAGTGGGAGAAAGATGCTGTACCTGCTTTGATAGGGCCATCGACTAAATACAAA GGAATTCTGGCTTTTAAAGACAGTAGGTACGAATTTTACCCAATTGATGTCGTTTTTCCTGTACTTCACGGTCCTAATGG AGAAGATGGAACAGTTCAGGGTCTTTTAGAGCTTTTAGAGATGCCGTACGTGGGTCCAAATGTACTGTCATCATCCTTAT GCATGGACAAAGTTTTTTCAAAGAGGATTTTTTTAGAGGCTGGAATACCTACGCCTAAATTTACAGTTGTGTATAGAAAA GAGTTAAATAATGTAGATAATTACGAAGAAATACGAAGAAGAGTATCAGAGATTGGATATCCGTGCTTTGTAAAACCTGC AAATATGGGCTCAAGCGTAGGTATAACGAAGGTTCACAATGAAAATGAACTGATGGATGGCTTGAAATTGGCGTCAAAGT ATGATAGAAAAATTATTATAGAAGAAGGAATAGATGCAAGGGAGATTGAGTGCTCAGTTCTAGGCAATGATAATCCTGAG GCATCTATTGCTGGTGAGATAGTCCCGGCACATGAATTTTACGATTACGATGCGAAATATTTCGATGAAGCATCGAAGCT TTTTATACCAGCACCTATACCAGATGTTAAGATGGAAGAGATAAGAGAGTTAGCGATTAAAGCATATATTGCATTGGACG TAAGAGGAATGGCAAGGGTTGACTTTTTGATGGACAAAAATACCGGTAAAGTTTACCTAAATGAATTGAATACTATACCT GGATTCACGAAAATTAGCATGTATCCGAAGCTTTGGGAAGCATCAGGGAAACCGTATAGCAAATTAATCGATGACCTGAT CCAATTGGCTTTATCTGCCAATAAAGAGAAATGTACAAACTGGTAA Protein sequence : MEKLKVAVLFGGQSGEHEVSRVSATSIINNIDRDKYDVYMVGITKKGEWYLYNGDIEKIATGEWEKDAVPALIGPSTKYK GILAFKDSRYEFYPIDVVFPVLHGPNGEDGTVQGLLELLEMPYVGPNVLSSSLCMDKVFSKRIFLEAGIPTPKFTVVYRK ELNNVDNYEEIRRRVSEIGYPCFVKPANMGSSVGITKVHNENELMDGLKLASKYDRKIIIEEGIDAREIECSVLGNDNPE ASIAGEIVPAHEFYDYDAKYFDEASKLFIPAPIPDVKMEEIRELAIKAYIALDVRGMARVDFLMDKNTGKVYLNELNTIP GFTKISMYPKLWEASGKPYSKLIDDLIQLALSANKEKCTNW |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 2e-56 | 42 |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 7e-57 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | AY145441.gene.p01 | Protein | 1e-57 | 42 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | AF310956.2.orf5.gene | Protein | 4e-57 | 42 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | AF130997.1.orf4.gene | Protein | 5e-53 | 42 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | AF277571.gene.p01 | Protein | 1e-54 | 42 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | U35369.1.gene6.p01 | Protein | 3e-57 | 41 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | AE016830.1.gene2250. | Protein | 3e-57 | 41 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | U00456.gene.p01 | Protein | 3e-57 | 41 |
| Tthe_0219 | YP_003850878.1 | D-alanine/D-alanine ligase | AY489045.gene.p01 | Protein | 1e-53 | 41 |
