Gene Information

Name : Tthe_2115 (Tthe_2115)
Accession : YP_003852677.1
Strain : Thermoanaerobacterium thermosaccharolyticum DSM 571
Genome accession: NC_014410
Putative virulence/resistance : Unknown
Product : GMP synthase, large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2111133 - 2112671 bp
Length : 1539 bp
Strand : -
Note : KEGG: tpd:Teth39_1719 GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; tRNA methyl transferase-like; glutamine amidotransferase class-I

DNA sequence :
ATGGGGATTAATAGAGAAGTTATATTAATTCTTGACTTCGGCGGACAATATACACAATTGATTGCAAGGAGAATAAGGGA
AGCAAATGTTTTTTGTGAAATTGTTCCATACAACATAAAACCAGAAGAAATTATAAAGAAACAGCCAAAAGGATTGGTCT
TGTCAGGCGGACCTGCTAGCGTATACGCAGAGAATGCGCCAATATGCGATGAGGGAATTTTTAAATTAAATTATCCAATT
CTTGGTATATGTTATGGCGCACAACTTATGACTATGATGCAAGGCGGTAAAGTTGCGGAGGCTCCTGTAAGAGAGTATGG
AAAGACGGATGTTGTCATAAATAACAATATACCTTTGTTTAAAGGAATTGAAAAAGAGACAAGCTGTTGGATGAGCCATA
CAGATCAAATAGAACTGCCTCCCAAAAATTTTAAAGTCGTTGCATCAACTGCAAACTGTCCGATTGCGGCAATTGCAAAT
GTAGAAGGAAGGCAATATGCCGTACAATTCCATCCTGAAGTCATTCATACTCCAAGGGGTACTGAAATCATCAGAAATTT
CTTGTTTGAGATTTGTGACTGCTCTGCAGATTGGACGATGGATTCACTGATAGAGCAGACTGTCAAAGAAATAAGGCAAA
AGGTAGGAAAGGACAATGTAGTTTGTGCATTAAGCGGTGGTGTTGATTCATCTGTTGCTGCAGTTTTAGTTAACAGGGCA
ATACACGATCAGCTAGTATGTATTTTTGTTGATAATGGTCTTTTAAGGAAAAATGAAGGAGAAAAAGTAGTTGAAACCTT
CAAGAATAATTTTGATATGGAGATAATAAAAGTTGATGCAAAAGATAGATTTCTGGAAAAGTTGAAAGGAGTAAAAGATC
CTGAGCAAAAGAGGAAAATAATAGGAAATGAATTTATTGAAGTCTTTAAAGAAGAAGCTAAGAAAATTGGCGATGTAAAA
TATCTTGTGCAAGGGACACTTTATCCAGATGTTATCGAAAGCGGAAGCCCCGTTGCTTCAACAATAAAGAGCCATCACAA
TGTTGGCGGTCTTCCTGAAAATGTTGGTTTTGAGCTTATAGAGCCTTTAAGGATGCTTTTTAAAGACGAAGTAAGACAGG
TTGGGCGAGAACTTGGCATGCCTGATGAAATTCTAAATAGGCAGCCGTTCCCGGGACCGGGGCTTGCAGTAAGGATACTT
GGGGAAGTCACTGAAGAAAAATTAAATATATTAAGAGAAGCTGACAGTATAGTTTTAAGAGAGATGAAGAAAAATGGCTG
GTATAACAACGTATGGCAATCATTTGCTGTACTGCCTGACATAAAAAGTGTAGGAATAATGGGGGATGACAGGACATATG
CATATCCTATTATCTTAAGGATAGTTGAAAGTAATGACGGAATGACAGCAGATTGGGTTAAGATTCCGTATGATATTCTT
GAGGACATCTCCACAAGTATCATAAATGAAGTGTATGGCGTAAATAGAGTGCTGTATGATATCACGTCAAAACCGCCTGC
CACCATTGAATGGGAATAA

Protein sequence :
MGINREVILILDFGGQYTQLIARRIREANVFCEIVPYNIKPEEIIKKQPKGLVLSGGPASVYAENAPICDEGIFKLNYPI
LGICYGAQLMTMMQGGKVAEAPVREYGKTDVVINNNIPLFKGIEKETSCWMSHTDQIELPPKNFKVVASTANCPIAAIAN
VEGRQYAVQFHPEVIHTPRGTEIIRNFLFEICDCSADWTMDSLIEQTVKEIRQKVGKDNVVCALSGGVDSSVAAVLVNRA
IHDQLVCIFVDNGLLRKNEGEKVVETFKNNFDMEIIKVDAKDRFLEKLKGVKDPEQKRKIIGNEFIEVFKEEAKKIGDVK
YLVQGTLYPDVIESGSPVASTIKSHHNVGGLPENVGFELIEPLRMLFKDEVRQVGRELGMPDEILNRQPFPGPGLAVRIL
GEVTEEKLNILREADSIVLREMKKNGWYNNVWQSFAVLPDIKSVGIMGDDRTYAYPIILRIVESNDGMTADWVKIPYDIL
EDISTSIINEVYGVNRVLYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-142 57
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-143 57
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-142 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-132 52