Gene Information

Name : COB47_0921 (COB47_0921)
Accession : YP_003840214.1
Strain : Caldicellulosiruptor obsidiansis OB47
Genome accession: NC_014392
Putative virulence/resistance : Virulence
Product : N-acetylneuraminate synthase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2089
EC number : 2.5.1.56
Position : 1035235 - 1036281 bp
Length : 1047 bp
Strand : +
Note : TIGRFAM: N-acetylneuraminate synthase; KEGG: fjo:Fjoh_0305 N-acetylneuraminic acid synthase domain-containing protein; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein

DNA sequence : 
ATGAAAAAACCCTTTATACAAATCGGTAACAGAAAAATAGGAGAAGATTATCCACCTTTAGTAATAGCAGAGATAGGAAT
AAATCATGGAGGAAGTTTAGAGGTAGCAAAAAAAATGGTAGATGCGGCATACGAAGCGGGGGCTGAGGTAATTAAACATC
AAACGCATATTGTAGAAGATGAAATGAGTAAAGAAGCAAAAAAAGTTATTCCTGGGAATGCAAATGTTTCTATTTATGAA
ATCATAAAAAGATGTGCTTTGAGTGAAGAAGAAGAATATGAATTGAAAAGATACGTTGAATCGAAAGGTATGATTTTTTT
AAGTACACCCTTTTCAAAAGCAGCAGTTGATAGATTAGTGAAAATGGATGTTCTTGCATTTAAAGTGGGTTCAGGTGAGT
GCAACAATTATCCACTTATTGAGTATATCGCATCGTTCGGTAAACCAATGATAGTTTCAACAGGGATGAATGATATAAAA
AGTGTTAAGAAAACGGTAGAGATATTGGAAAAGTATAATATTCAATATGCTCTACTACATTGTACTAATTTGTATCCTAC
GCCACCCCATTTAGTAAGACTTGGCGGCTTATTAGAACTGAAAGAAACTTTTCCGAATGCAGTTATTGGATTATCAGATC
ATACTGTTAATAATTATGCTTGTTTAGCAGCTGTAGCTTTAGGTGCTTCTATCCTTGAAAGGCATTTTACGGATTCTAAA
GACAGACCGGGACCTGATATTGTCTGTTCAATGGACCCCAAAGAATTAAAAGAACTAATTGAAGCAAGTGCTCAAATTGC
TTTAATGCGTGGTGGGAAAAAAGAACCAGTACCTGAAGAGAAAGTTACAATGGATTTTGCTTTTGCCACTGTTGTTGCAA
TTAAGAATATTAAAGCTGGAGATGTATTAACAAAGGATAATATTTGGGTAAAAAGACCTGGTATAGGTGAAATAAAGGCA
GAGTATTACTATGATTTGTTAGGGAAGAGAGCAAAAAGGGATATATTGGAGGATGAACATTTAAGATGGGAAGATATTGA
ACTCTAA

Protein sequence : 
MKKPFIQIGNRKIGEDYPPLVIAEIGINHGGSLEVAKKMVDAAYEAGAEVIKHQTHIVEDEMSKEAKKVIPGNANVSIYE
IIKRCALSEEEEYELKRYVESKGMIFLSTPFSKAAVDRLVKMDVLAFKVGSGECNNYPLIEYIASFGKPMIVSTGMNDIK
SVKKTVEILEKYNIQYALLHCTNLYPTPPHLVRLGGLLELKETFPNAVIGLSDHTVNNYACLAAVALGASILERHFTDSK
DRPGPDIVCSMDPKELKELIEASAQIALMRGGKKEPVPEEKVTMDFAFATVVAIKNIKAGDVLTKDNIWVKRPGIGEIKA
EYYYDLLGKRAKRDILEDEHLRWEDIEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
siaC NP_273132.1 polysialic acid capsule biosynthesis protein SiaC Not tested IHT-A Protein 1e-102 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
COB47_0921 YP_003840214.1 N-acetylneuraminate synthase VFG0252 Protein 4e-103 65