Gene Information

Name : COB47_0815 (COB47_0815)
Accession : YP_003840113.1
Strain : Caldicellulosiruptor obsidiansis OB47
Genome accession: NC_014392
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 945365 - 946708 bp
Length : 1344 bp
Strand : +
Note : KEGG: ate:Athe_0882 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein

DNA sequence :
ATGGAGCCCGACATTGTTCAAAATCAAAGTGAGATGCCTGAAAGCCGCGAAGCAGAAGAAGCGGTTGTAGGGGCGATGCT
TTTAAGCCGCGAAGTAATTTCTGATGTTACTGAGATTTTGACAGAAGAGGATTTTGCAACGCCCCAGCTAAAAGAGATTT
TTGCTGCTATTATGGACCTTTTTGAAGAGGGCAAACCGGTAGATGTCATAACTGTAGCTGAGAGACTGAGAGAAAGAGGT
ACATTTGATGCAGTTGGAGGAAATGAGTATCTGACAAACCTTGTGATAAATACTCCGACAACTGCAAATGCTACATATTA
TGCAAAGATTGTTGAAGAAAAGTCACTACTTAGGAAACTCATAAACTCTTCAATGAAGATTATTGAAAAGTGTAAGAGTC
AGACAGAAAGAGTTGAAGATATTGTTGATTTTGCTGAAAAGACAATCTTCAATGTGATTTCTCACAAAAATTCAAAAGAT
TTTTCTCATTTAAAAGAGATATTAATTGAAACATATAACAAGATAGAGGAACTGTATCTCAGAAAATCGCATATTATAGG
TGTACCCACAGGATTTGCTGAGTTTGACAGAATGACAGCAGGTCTTCAGCCATCAGACCTGATACTTATTGCAGCAAGAC
CTGCAATGGGGAAGACAAGTTTTGCACTCAATATTGTTCAGCATGCAGCTTTGAGAGCTGGTGTGCCCGTAGCGGTATTT
AGTCTTGAGATGTCAAAAGAACAGCTTGTAACCCGTATGATTTGCTCAGAAGCAATGATAGATAGCCACAAGCTTAGAAC
TGGAAACTTAGAGGATGAAGAGTGGAAAAAGTTTGCAAAAGCTTTAGCACTTTTGTCAAACGCTCCAATTTATATTGACG
ATACACCTGCCATAACTGTTGCAGAAATGAGGGCAAAATGTAGAAGACTCAAGCTCAAAGAAAAAGGCCTTGGGCTTGTG
ATGGTTGACTATTTGCAGCTTATGACCGCTCGTGGCAGGTTTGAGAGCAAGCAACAGGAAATTGCAGAGATTTCAAGGTC
ATTAAAAGCCTTGGCAAGAGAGCTAAATGTTCCTGTACTTGCGCTTTCGCAGCTATCCCGCGCACCTGAAACAAGAGCTG
ACCACAGACCTATTCTTTCCGACCTTCGAGAAAGTGGCGCAATTGAACAGGATGCAGACATTGTTGCTTTTTTGTACAGA
GATGAGTATTACAATCCTGACACTGACAAAAAACACATTGCAGAGCTAATAATTGCAAAGCACAGAAATGGACCTACTGG
CACAATTGAACTTCTTTTCTTGGACAAACATACCAAGTTCAAAGATTTGGAGAAGAATAGATAA

Protein sequence :
MEPDIVQNQSEMPESREAEEAVVGAMLLSREVISDVTEILTEEDFATPQLKEIFAAIMDLFEEGKPVDVITVAERLRERG
TFDAVGGNEYLTNLVINTPTTANATYYAKIVEEKSLLRKLINSSMKIIEKCKSQTERVEDIVDFAEKTIFNVISHKNSKD
FSHLKEILIETYNKIEELYLRKSHIIGVPTGFAEFDRMTAGLQPSDLILIAARPAMGKTSFALNIVQHAALRAGVPVAVF
SLEMSKEQLVTRMICSEAMIDSHKLRTGNLEDEEWKKFAKALALLSNAPIYIDDTPAITVAEMRAKCRRLKLKEKGLGLV
MVDYLQLMTARGRFESKQQEIAEISRSLKALARELNVPVLALSQLSRAPETRADHRPILSDLRESGAIEQDADIVAFLYR
DEYYNPDTDKKHIAELIIAKHRNGPTGTIELLFLDKHTKFKDLEKNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-64 43
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 6e-65 42
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 1e-66 41
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 6e-62 41
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 8e-66 41