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Name : COB47_1809 (COB47_1809) Accession : YP_003841071.1 Strain : Caldicellulosiruptor obsidiansis OB47 Genome accession: NC_014392 Putative virulence/resistance : Resistance Product : D-alanine--D-alanine ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : 6.3.2.4 Position : 1947668 - 1948762 bp Length : 1095 bp Strand : - Note : TIGRFAM: D-alanine/D-alanine ligase; KEGG: ate:Athe_2039 D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein DNA sequence : ATGACCAAGTTAAAAGTTGCTGTTTTGTTTGGAGGAGTTTCAACAGAGCACGAAATATCCATAGTTTCGGCAAAATCAAT TATGCAAAATATGGACAAGGAAAAATACGAAATAATTCCAATAGGTATAACAAAAGAAGGAAAATGGCTCTTGTACACAG GCAAAATTGAAGATTTGGATAGCAAATGGACTCAGTTTTCTATAGAATGTTTTGTCTCTCCTGATAGAACCAAAAAGGCA CTTGTAAAAATAAAAGATAACGAGGCTACCTTTATCGACATTGACGTGGTTTTTCCGGTTTTGCATGGACTGAATGGTGA GGACGGGACAGTTCAGGGACTTTTAGAGTTATCTAACATACCGTATGTGGGCTGCGGTGTTCTTTCGTCGGCTATATGTA TGGACAAAGCATTTGCTAAAAAGCTTGCGCTTTTAGAAGGAATACCACAGGGGCATTTTTTAGTTGTATACAAAAACGAA TATTCAGCTAAAAAAGATTATTTCATAAGAAGAATAGAGAGTGAGTTTTCGTATCCTGTTTTTGTAAAGCCTGCAAACTC AGGCTCGTCTGTGGGTATATCAAAAGCGAAAGATAGAGAAGACCTTGTTTTGGCGATACATGAGGCTTTTTTGTATGATA CAAAGGTTTTGATTGAACAGGCTATAAACGCTCGGGAGATAGAATGTGCAGTTTTGGGAAATGATGAGGTATTTGTGTCT GAGCCGGGTGAAATAATTCCATCAAGAGAGTTTTATTCGTATGAAGCAAAATATATTGATGATTCATCAGAGCTCATCAT CCCGGCAAGACTTCCAAAAGAAGTTACTGAAGAGATAAAAGATTTGGCAGCAAGGATTTACAAAATTTTTGAGTGCTGTG GAATGGCAAGAGTGGACTTTTTTGTTGATAAAGATACGAACAAAGTGTATTTCAACGAGGTAAACACAATACCTGGTTTT ACAAGTATTTCGATGTATCCAAAACTTATGGAGTTCAGTGGTATTCCATATTCTCAGCTCATTGATAAACTAATTTCTCT TGCCATTGAGAAGAATGAGCAGAAAAAAAGCATAAAATACAGCAAAGAGGGCTGA Protein sequence : MTKLKVAVLFGGVSTEHEISIVSAKSIMQNMDKEKYEIIPIGITKEGKWLLYTGKIEDLDSKWTQFSIECFVSPDRTKKA LVKIKDNEATFIDIDVVFPVLHGLNGEDGTVQGLLELSNIPYVGCGVLSSAICMDKAFAKKLALLEGIPQGHFLVVYKNE YSAKKDYFIRRIESEFSYPVFVKPANSGSSVGISKAKDREDLVLAIHEAFLYDTKVLIEQAINAREIECAVLGNDEVFVS EPGEIIPSREFYSYEAKYIDDSSELIIPARLPKEVTEEIKDLAARIYKIFECCGMARVDFFVDKDTNKVYFNEVNTIPGF TSISMYPKLMEFSGIPYSQLIDKLISLAIEKNEQKKSIKYSKEG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 1e-59 | 43 |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 6e-59 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | NC_005054.2598280.p0 | Protein | 1e-60 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | NC_014475.1.orf3.gen | Protein | 1e-60 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | AF130997.1.orf4.gene | Protein | 3e-58 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | U35369.1.gene6.p01 | Protein | 6e-60 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | AE016830.1.gene2250. | Protein | 6e-60 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | AF310956.2.orf5.gene | Protein | 9e-60 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | U00456.gene.p01 | Protein | 6e-60 | 43 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | AF277571.gene.p01 | Protein | 3e-58 | 42 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | AY145441.gene.p01 | Protein | 9e-60 | 42 |
| COB47_1809 | YP_003841071.1 | D-alanine--D-alanine ligase | AY489045.gene.p01 | Protein | 4e-56 | 42 |
