Gene Information

Name : COB47_1291 (COB47_1291)
Accession : YP_003840569.1
Strain : Caldicellulosiruptor obsidiansis OB47
Genome accession: NC_014392
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1409518 - 1411269 bp
Length : 1752 bp
Strand : -
Note : KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
TTGAGAAAAACAAAAATAATTTGTACATTGGGTCCAGCGAGCGACTCAGAGGAGATAATAAGAAAGCTTGTTGAAAATGG
AATGGATGTTGTGAGATTAAATTTTTCTCATGGTACTCATGAAGAGCATAAGAAAAAGATTGACATGGTAAAAAAAATAA
GAGAAGAACTTGACAAGCCTATTCCCATTTTGCTTGATACCAAGGGTCCAGAGATAAGAATAGGCTTTTTTAAGGATGGC
AAAGTAGAACTAAAAGAGGGCCAGAAATTTGTGCTGACTACAGAAGAAATCTTGGGAAATGAAGAGATTGTGAGTATAAC
TTATAAAGAACTTATTGAGGATGTAAAACCAGGTGATAAAATCCTGATAGATGATGGACTTATTGAGCTTATTGTTGAGG
ACAAGACAGAAAAGAATATAATCTGCAAGGTAAAAAATGGAGGAGTTTTAACCAACCAGAAAGGGGTAAATGTACCGGGT
ATACCCATAAGACTTCCTGCACTTACCCAGAAGGATAAAGAGGATATTCTGTTTGGAATAGAAAACGATGTAGATTTTAT
TGCAGCCTCATTTATAAGAAAGGCAAGTGACGTTGTTGAAATCAGAGAGTTTCTGAACAAAAATGGTGGAAAAGATGTTT
TAATAGTTGCCAAGATAGAAACTCAAGAAGGTGTTGCCAACTGCGACGAAATAATAAGGGTTGCAGATGGGATTATGGTT
GCAAGAGGAGATTTAGGGGTAGAACTTCCTTTTGAGGAAGTTCCCCTTGTTCAAAAGATGCTGATTGAGAAGTGTTACAA
AGCAGGAAAGCCTGTCATAACAGCAACCCAGATGCTTGAATCTATGATACGAAATCCAAGACCTACCAGGGCAGAGGTTA
GCGATATTGCCAATGCCATATTTGATGGCACTTCTGCAATAATGCTCTCTGGCGAGACGGCAATGGGCAAGTACCCCGTT
GAAAGTGTTGCTACAATGGCAAAGATTGCCGAGAGAGTAGAAAATCAGATTGATTATATCAAGAGATTTCAATCTCAGGT
ATTTGATATGCCTGTTAATGTGACAAATGCTATTTCGCACGCAACTTGTACAACCGCACATGACCTTGGCGCAAAGGCTA
TTATAACAGTGACAAAGTCAGGTAACACTGCAAGAATGGTGTCAAAATTCAGACCTGCTTGTCCGATTATTGCAACCACA
CCTTGTGAGAAGGTAAGAAGACAGTTGAATTTGTCATGGGGTGTATATCCATTTCTGGCAGAGTACAAGAGTTCAACCGA
TGATATATTTGACCATGCTGTTGAGATAGCTGTGAAATCCAAGATTGTAAAAAATGGAGATTTAGTTGTTATCACTGCCG
GAGTTCCTGTTGGTGTGAGTGGAACAACAAATATACTTAAAGTTCATGTTGTAGGACATGTTCTGGTTGAAGGACGTGGC
TGGGGAAGTGGAAAGGTAACAAGCAGGGTCTGTGTTGTAAAAACCATTAATGATTTAAAGCTGAATTTTGAAGATGGAGA
TATTATTGTTACAAATCAAACAAATAACGAGTTTATACCATATATGAAAAGAGCATCTGGAATTATCACAGAAGAAGGTG
GACAGAACTCTCATGCTGTAATTGTAGGTGCTGCACTTGATATCCCTGTAATTACAGATGCTAAAAATGCATTAGAGATA
TTAAAAACAGGGATTGTGGTTACAATTGATACTCAAAAAGGCATTGTATTTAGTGGAGAACAGAAGGTATAA

Protein sequence :
MRKTKIICTLGPASDSEEIIRKLVENGMDVVRLNFSHGTHEEHKKKIDMVKKIREELDKPIPILLDTKGPEIRIGFFKDG
KVELKEGQKFVLTTEEILGNEEIVSITYKELIEDVKPGDKILIDDGLIELIVEDKTEKNIICKVKNGGVLTNQKGVNVPG
IPIRLPALTQKDKEDILFGIENDVDFIAASFIRKASDVVEIREFLNKNGGKDVLIVAKIETQEGVANCDEIIRVADGIMV
ARGDLGVELPFEEVPLVQKMLIEKCYKAGKPVITATQMLESMIRNPRPTRAEVSDIANAIFDGTSAIMLSGETAMGKYPV
ESVATMAKIAERVENQIDYIKRFQSQVFDMPVNVTNAISHATCTTAHDLGAKAIITVTKSGNTARMVSKFRPACPIIATT
PCEKVRRQLNLSWGVYPFLAEYKSSTDDIFDHAVEIAVKSKIVKNGDLVVITAGVPVGVSGTTNILKVHVVGHVLVEGRG
WGSGKVTSRVCVVKTINDLKLNFEDGDIIVTNQTNNEFIPYMKRASGIITEEGGQNSHAVIVGAALDIPVITDAKNALEI
LKTGIVVTIDTQKGIVFSGEQKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-105 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
COB47_1291 YP_003840569.1 pyruvate kinase VFG0479 Protein 3e-106 51