Gene Information

Name : COB47_1067 (COB47_1067)
Accession : YP_003840352.1
Strain : Caldicellulosiruptor obsidiansis OB47
Genome accession: NC_014392
Putative virulence/resistance : Resistance
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1189563 - 1190261 bp
Length : 699 bp
Strand : +
Note : KEGG: ate:Athe_1487 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver

DNA sequence :
ATGAAAAGCATTTTAATAGTTGATGATGAGCAGCATATTCTTGAACTTCTCAAATTTAATCTTAGGAAAGAAGGATATAA
TACATTTGAAGCGGACAGTGGAGTACAGGCATTGGAGATTTTAAAGAATAACAAAGTTGATCTTGTCATACTTGATATTA
TGATGAGTGACAAGGATGGATATGAAGTTTTAAAAGAGATTCGATTCAATAGAGATACTAAAAATCTTCCGGTGATTTTG
CTGTCTGCTAAATCTGAAGAGATTGATAAGATACTTGGGCTTGAGCTCGGAGCAGATGACTATATAACAAAGCCTTTTAG
TGTAAAAGAGCTGGTTGTAAGAGTGAAGGCACTTTTAAGAAGAGTAGAGAGTTTAAAGCCTGAGGTTGAAGATAAGGTCA
AGTTTGGAGATGTAGAAGTGGACTTTTCAAAAAGAACTGTCAAGAAAAATAACCAGGATGTATCTCTTTCGTTCAAAGAA
TTTGAGCTTCTGAAGCTTCTTATCGAAAACAAAGGCAGGGTGTTGGACAGAGACTTTATTTTGCAAAGGGTATGGGGATA
CGAGTTTGATGGAGATACACGAACGGTTGACGTACACATAAGGTTTTTGAGGAGAAAACTTGAAGATGATGAGAAAAATC
CGCGTTACATAGAAACTGTCAGGGGTGTGGGATACAGGTTTAATGAAAGGTCTGAGTAA

Protein sequence :
MKSILIVDDEQHILELLKFNLRKEGYNTFEADSGVQALEILKNNKVDLVILDIMMSDKDGYEVLKEIRFNRDTKNLPVIL
LSAKSEEIDKILGLELGADDYITKPFSVKELVVRVKALLRRVESLKPEVEDKVKFGDVEVDFSKRTVKKNNQDVSLSFKE
FELLKLLIENKGRVLDRDFILQRVWGYEFDGDTRTVDVHIRFLRRKLEDDEKNPRYIETVRGVGYRFNERSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 3e-23 41
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 3e-21 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 6e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 6e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 8e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 6e-36 49
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 2e-33 48
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator NC_012469.1.7686381. Protein 4e-31 47
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator AE016830.1.gene1681. Protein 2e-35 45
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator FJ349556.1.orf0.gene Protein 2e-32 45
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator AF155139.2.orf0.gene Protein 2e-31 44
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 2e-32 44
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 2e-31 44
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator AF310956.2.orf0.gene Protein 1e-23 41
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator AE016830.1.gene2255. Protein 1e-21 41
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator U35369.1.gene1.p01 Protein 1e-21 41
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator BAC0308 Protein 5e-22 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator VFG1389 Protein 3e-24 45
COB47_1067 YP_003840352.1 winged helix family two component transcriptional regulator VFG1386 Protein 5e-31 41