Gene Information

Name : COB47_1046 (COB47_1046)
Accession : YP_003840331.1
Strain : Caldicellulosiruptor obsidiansis OB47
Genome accession: NC_014392
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1163286 - 1165880 bp
Length : 2595 bp
Strand : +
Note : TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; KEGG: ate:Athe_1508 ATP-dependent chaperone ClpB; SMART: AAA ATPase

DNA sequence :
ATGAATATGGAAAGATTTACTCAAAGTCTTCAAACAACTCTTTTAGATGCTCAAAATACAGCTATTGTTTACAAGCATCA
GGAAATAGGAGTAGAGCATCTCCATTATGCACTTGTGAATGAAGATGATAAACTTGTAGCAAAGATTCTTAAAAACATGG
GTATTGACATAGAGCTTTATAAAAGAGATATTGAAGAGCAGCTGAAAAAGATTCCAATGGTATACGGACCTGGTGCTTCA
ACGGTATACGTAAGTAGATATGTAAACGAAATTTTAATCAAAGCTGAAGAAGAAGCAAAAAAGTTTAAAGACGAATATAT
AAGCGTTGAACATGTTTATTTAACTATGATAGACTCAGATATCCCTTCCGCCAAGAATATATTTAGAAAATATGGAATTA
CACACGAAAAATTTTTACAGCAGCTTTATAAAATTAGGGGAAATCAAAGAATAACAAGTCCTAACCCCGAGGAAGTCTAT
GAGGTTTTAAAAAAGTATGGACGGGACCTTACCGATCTTGCGAGAAAAGGCAAGCTTGATCCTGTAATTGGAAGAGATGA
TGAAATAAGGAGAGTTATTCAAATTCTTTCTCGCAGAACAAAAAATAACCCTGTTTTGATTGGTGAACCTGGAGTTGGTA
AAACTGCTATTGTTGAAGGACTTGCACAAAGAATTGTAAAAGGAGATGTTCCAGAGGGGCTTAAAGACAAGACAATTTTT
GCTCTTGATTTGGGTGCCCTCATTGCAGGTGCAAAATATAGAGGTGAGTTTGAAGAAAGGCTGAAAGCTGTTTTAAATGA
AATCATTGCTTCTGAAGGTAAGATAATACTTTTTATTGATGAAATACACAACATAGTTGGAGCAGGAAGAGCAGAAGGTG
CTATGGATGCAGGAAACCTTTTAAAGCCCATGCTGGCGAGAGGAGAACTGCATTGTATCGGTGCAACAACAATTGATGAA
TATAGAAAATATATAGAAAAGGATGCTGCACTTGAGAGAAGATTTCAGCCTGTTTTAGTAAATCCTCCATCTGTTGAAGA
TACCATTTCTATTTTGCGAGGACTTAAAGAAAGATTTGAAATCCATCATGGAGTACGAATTACAGATGATGCTTTGATTG
CAGCAGCAAAGCTTTCAGACAGATATATTTCAGATAGATTCTTGCCTGACAAAGCAATCGATTTGATTGATGAAGCAGCT
GCACTATTGAGAACAGAGATAGACTCAATGCCCACAGAACTGGATGAAATTACAAGAAAGATTATGCAGCTAAGAATTGA
AAAAAATGTCTTGCAAAAAGAAGAAAATACGAGCGCAAAACAGCGCATAGAGGAGATTGAAAAGGAAATTGCGCAGCTTC
AATCCAGAGCAGATGAACTTTCAGCTCAGTGGGAATATGAGAAAGAGTTGATAAAAGATATAAGAAGAATAAAAGAGGAG
ATTGAAAATGTTAAGATTCAAATTGAAGAGGCTGAAAGAAACTATGACCTCAATAGACTTTCTGAGCTGAAATATGGCAA
GCTCATAGAACTGCAAAAAGCTTTAGATAGAAAACGTCAGGAGTTAGAAAAAATACCACCAGAAAAAAGACTTTTAAAAG
AGGAAGTAACAGAAGAAGAAATTGCAAAGATTGTATCAAAGTGGACAGGAATTCCGGTTGCAAAGCTTGTAGAGACTGAA
AGGCAAAAGATTTTAGAGCTTGATAAAATCTTGCACAAAAGAGTTGTTGGTCAAGATGAAGCAATTGAAGCTGTGTGCAA
TGCAATAATGAGAGCGCGAGCTGGAATAAAAGATCCGAGAAAACCAATAGGTAGCTTCTTGTTTTTAGGTCCAACAGGTG
TTGGTAAAACAGAACTTGCAAGAGCGTTAGCTGAAGCTCTGTTCGATTCTGAAAACAATATGATAAGAATTGACATGACA
GAGTATATGGAGAAACACTCAGTTTCGCGCTTGATTGGTGCACAACCTGGGTATGTGGGATATGAAGAAGGAGGTCAACT
TACAGAGGCTGTTAGAACCAAACCTTATTCAGTTGTACTTTTTGATGAAATTGAAAAAGCACATAGAGATGTTTTTAATA
TTCTCCTACAAATAATGGATGATGGTAGACTTACTGATTCTAAAGGCAGAACAGTGGATTTTAAGAATACTATAATTATA
ATGACTTCTAACTTGGGAAGCGAATATCTTTTGAACGCTAAGATTTCAAATGGTGAAATAGATGAAGAGACACGGAAACT
GATAGATAGAGAATTAAAATTACATTTTAGACCAGAGTTTTTAAACAGACTTGACGAGATAATAATCTTCAAACCTCTCA
CAAAGGAGCAGATTATAAAAATTATCGACCTTCGAGTTGCAGAAATTCAGCAAAAGCTGATAGAAAAAGGAATTTCAATA
AGGTTGACCCAAAAGGCAAAAGAGTTTATTATGGAAAATGCCTTTGATATAAACTTTGGTGCAAGACCAATAAAGAGATT
CTTGCAGAAAAATGTTGAAACACTTATAGCAAGAGAGATTTTGAAAGGTACAATTGTTGAAGGTGAAAGTATTGATATAG
ATGTTGAAAACGGAAGGTTTGTTATAGTAAAATAA

Protein sequence :
MNMERFTQSLQTTLLDAQNTAIVYKHQEIGVEHLHYALVNEDDKLVAKILKNMGIDIELYKRDIEEQLKKIPMVYGPGAS
TVYVSRYVNEILIKAEEEAKKFKDEYISVEHVYLTMIDSDIPSAKNIFRKYGITHEKFLQQLYKIRGNQRITSPNPEEVY
EVLKKYGRDLTDLARKGKLDPVIGRDDEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKDKTIF
ALDLGALIAGAKYRGEFEERLKAVLNEIIASEGKIILFIDEIHNIVGAGRAEGAMDAGNLLKPMLARGELHCIGATTIDE
YRKYIEKDAALERRFQPVLVNPPSVEDTISILRGLKERFEIHHGVRITDDALIAAAKLSDRYISDRFLPDKAIDLIDEAA
ALLRTEIDSMPTELDEITRKIMQLRIEKNVLQKEENTSAKQRIEEIEKEIAQLQSRADELSAQWEYEKELIKDIRRIKEE
IENVKIQIEEAERNYDLNRLSELKYGKLIELQKALDRKRQELEKIPPEKRLLKEEVTEEEIAKIVSKWTGIPVAKLVETE
RQKILELDKILHKRVVGQDEAIEAVCNAIMRARAGIKDPRKPIGSFLFLGPTGVGKTELARALAEALFDSENNMIRIDMT
EYMEKHSVSRLIGAQPGYVGYEEGGQLTEAVRTKPYSVVLFDEIEKAHRDVFNILLQIMDDGRLTDSKGRTVDFKNTIII
MTSNLGSEYLLNAKISNGEIDEETRKLIDRELKLHFRPEFLNRLDEIIIFKPLTKEQIIKIIDLRVAEIQQKLIEKGISI
RLTQKAKEFIMENAFDINFGARPIKRFLQKNVETLIAREILKGTIVEGESIDIDVENGRFVIVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-98 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
COB47_1046 YP_003840331.1 ATP-dependent chaperone ClpB VFG2076 Protein 5e-115 43
COB47_1046 YP_003840331.1 ATP-dependent chaperone ClpB VFG2084 Protein 1e-104 41