Gene Information

Name : Acear_0543 (Acear_0543)
Accession : YP_003827151.1
Strain : Acetohalobium arabaticum DSM 5501
Genome accession: NC_014378
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 593967 - 594911 bp
Length : 945 bp
Strand : +
Note : COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: drm:Dred_2163 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; PRIAM: Hydroxymethylbilane synthase; SPTR: A4J6H7 Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; P

DNA sequence : 
ATGAAGGGTAATAAAGTAATTATCGGAACTAGAAGTAGTGATTTGGCTGTAGGGCAGGCGGAGATAGTAGCTGAAATGTT
GGGGAAGGCTGTTTCAGAGTATGAGTTTGAGTTAGAGAAGATCAAGACTAAAGGAGATAAGATCTTAGATAGTCCATTAT
CACAGGTAGGCGGTAAGGGATTATTTATTAAAGAATTAGAAGTTTCTTTGCTAGAAGAAGAAATAGATTTAGCAGTCCAT
AGTATGAAGGATATGCCAGCAGAGCTGCCGGAAGGTTTAGCAGTCCTTGGTTTTCCAGAGCGGGTGGATTCTAGGGATGC
TTTAGTATCTAATGGCGATCGTAATCTTGATGAGCTGCCAACCGGTGCTCGAATTGGAACCGGAAGTCTGCGGCGAACTT
CACAGCTGTTGAATTATCGACCTGATTTGGAGGTAGTACCGATTAGAGGAAATATTAATACTAGGCTGGAGAAGTTGACA
GCTGAAGAACTGAATTTAGATGCGATTGTACTGGCTGCAGCCGGCTTAATCAGAATGGGCTGGAAAGATAAAATTACTGA
ATATTTAGATGATGAAGTTATGCTGCCTGCAGCTGGCCAGGGGGCTTTAGCTATTGAAGCCAGAGAAGATGATGAAGAGA
TTAAGACATTGATTAATAAGATAGATGATCAAAGAACCCGTTATATTCTTCAGGCAGAACGGGGATTTTTGGAACGATTA
GATGGCGATTGTCAAGTGCCGATTGGTGCTTTAGCCGAGATAGAAGGAGAAGAGATTACGCTGGAAGGTATGGTAGCTAC
ACTGGATGGACAGAAACATCTCCGTGATCAGATCACAGGTTCTGTTGGAGAAGCTGAAGAATTAGGAATAGAACTAGCTG
AAGAGTTAATTGCTAAAGGAGCAGAGAAGATTCTACAACAGGCAAGACAGGAGACTGATAAATAA

Protein sequence : 
MKGNKVIIGTRSSDLAVGQAEIVAEMLGKAVSEYEFELEKIKTKGDKILDSPLSQVGGKGLFIKELEVSLLEEEIDLAVH
SMKDMPAELPEGLAVLGFPERVDSRDALVSNGDRNLDELPTGARIGTGSLRRTSQLLNYRPDLEVVPIRGNINTRLEKLT
AEELNLDAIVLAAAGLIRMGWKDKITEYLDDEVMLPAAGQGALAIEAREDDEEIKTLINKIDDQRTRYILQAERGFLERL
DGDCQVPIGALAEIEGEEITLEGMVATLDGQKHLRDQITGSVGEAEELGIELAEELIAKGAEKILQQARQETDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-49 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-49 49