Gene Information

Name : Acear_2325 (Acear_2325)
Accession : YP_003828871.1
Strain : Acetohalobium arabaticum DSM 5501
Genome accession: NC_014378
Putative virulence/resistance : Unknown
Product : primary replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 2444251 - 2445591 bp
Length : 1341 bp
Strand : -
Note : COGs: COG0305 Replicative DNA helicase; InterPro IPR007694:IPR007693:IPR016136:IPR007692; KEGG: nth:Nther_2910 primary replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SPTR: A1HRK0 Replicative DNA helicase; TIGRFAM: replicative

DNA sequence :
ATGGAAGCAGATTTAAATGATAATGTACCGCCTCACAGTATTGATGCTGAAAAATCAACTTTAGGGGCCATGTTAATTGA
CCGTGATGCTATAGCAAAGGCAATAGAGGTTCTAAGACCGGATGATTTCTACCGTAAGGCCCATGCTATCATTTATGAAG
TGATTAATGAGATCTTTGATAAAGGGGAACCGGTGGATTTAGTAACTGTTAGTGAGGAATTGAGGGCTAAAGAAGCCTTA
GAAGATATAGGAGGCGTAGCTTATCTTACTTCTCTGGCAGACAGTGTGCCAACGGCATCCAATATTACATATTATGCCAA
GATAGTAGAAGAGAAGTCGCTGCTTAGAAATTTAATTAAGTCAGCCAATCAAATTTCACAGTTAGGTTATCAGGGAGACA
AAGAAATAGATGTAGTGTTGGATAAAGCTGAACAGTTAATCTTTAATATTTCTCAAAAGAGATCAATCCAGGAGTATTCT
GGTATTCGAGATGTCTTAATGGATACCTTTGATAATTTAGAGAAGCTTTATGATAATAAGGATGGTGTAACCGGAGTTCC
AACAGGATTTAATGATTTGGATCAGATGACTTCTGGATTCCAGGAGTCTGATTTAATAATTATTGCTGCTCGTCCGAGTA
TGGGTAAGACTGCTTTAGCTTTAAATATAGCCCAGTATGCAGCAGTACAGGAGGATATACCGGTAGCAATCTTTTCTTTG
GAGATGTCAAAAGAACAGTTAGTCCAGAGGATGTTATGTTCTGAAGCTCAAGTGGATGGTCATCGCTTACGGACAGGTTA
TCTAAATGAGGATGACTGGAATCGGTTGACTAATGCTGCTGGAAACCTCAGTGAAGCTAATATTTTCATTGATGATACTC
CAGGAATTACAGCTATGGAGATGCGGGCTAAGGCCCGAAGGATGAAAGCTGAACATGGCTTAGGATTGATCTTAATTGAT
TACTTACAGTTAATGCAGGGGCAAGGGCGGGTAGAAAGTAGACAGCAGGAAGTTTCTAAAATATCCCGTTCATTAAAGGG
ATTGGCTAGAGAGCTGAATGTACCTGTTGTGTCCTTATCACAGTTAAGTAGAGCAGTAGAACAGCGGAATGATAAGCGGC
CTCAATTAAGTGATCTTCGTGCCAGCGGGAGTATTGAACAGGATGCAGATTTAGTTGCTTTTATCTATCGTGATGAATAT
TATAATCCTGATACTGAAAAACAGGGAATTACAGAGATTATTGTCGGTAAGCAGAGGAATGGACCAGTAGGAACAGTAGA
ATTAGCCTTTCAAAAGGAGTATACTAAATTTGTTGATTTAGCGGATAGGGAAGCACAATAA

Protein sequence :
MEADLNDNVPPHSIDAEKSTLGAMLIDRDAIAKAIEVLRPDDFYRKAHAIIYEVINEIFDKGEPVDLVTVSEELRAKEAL
EDIGGVAYLTSLADSVPTASNITYYAKIVEEKSLLRNLIKSANQISQLGYQGDKEIDVVLDKAEQLIFNISQKRSIQEYS
GIRDVLMDTFDNLEKLYDNKDGVTGVPTGFNDLDQMTSGFQESDLIIIAARPSMGKTALALNIAQYAAVQEDIPVAIFSL
EMSKEQLVQRMLCSEAQVDGHRLRTGYLNEDDWNRLTNAAGNLSEANIFIDDTPGITAMEMRAKARRMKAEHGLGLILID
YLQLMQGQGRVESRQQEVSKISRSLKGLARELNVPVVSLSQLSRAVEQRNDKRPQLSDLRASGSIEQDADLVAFIYRDEY
YNPDTEKQGITEIIVGKQRNGPVGTVELAFQKEYTKFVDLADREAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 1e-80 45
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 1e-80 45
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 4e-85 44
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 7e-80 44
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 3e-83 42
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 5e-81 42
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-82 42
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 8e-74 41