Gene Information

Name : Acear_1860 (Acear_1860)
Accession : YP_003828428.1
Strain : Acetohalobium arabaticum DSM 5501
Genome accession: NC_014378
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1956663 - 1958417 bp
Length : 1755 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR018313:IPR015793:IPR 015794:IPR008279:IPR015813:IPR015795:IPR011037; KEGG: hor:Hore_03220 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile

DNA sequence :
ATGAGAAGGACAAAGATTGTATGTACTATTGGTCCCGGAAGTGATGATGAAGAGACTTTATCACAGTTGATTGATGCTGG
AATGAATGTAGCGCGGATGAACTTTTCTCATGGTAATCACCAGGAGCATAAAGAAAGGATTCAAAGAGTAAGAAACTTAG
CTGCTCAGAAGGGAAAGCCGGTAGCTATTATGCTTGATACTAAAGGTCCAGAGGTTAGAACCGGTATGTTAAAGAATGAT
GAGGAGGTTACGCTAAAGGAAGGGGAGAAGTTTGTACTAACAACAGAAGAGATTGAAGGTGATGATAAGAGAGTATCTGT
TTCGTATAACGATCTTCCTAAAGATGTTGAAGTAGGCGGAACTATTCTGATTGATGATGGATTAATTGAATTGGAAATAG
ATAATATTTCTGATACTGAGGTAGAATGCACAGTGCTTAATGGTGGGCAGTTAGGATTACGTAAAGGAGTAAATCTGCCT
GGAGTTTCTGTTAATTTACCAGCAATTACTGACAAAGATGCAGCTGATATTAAGTTTGGAATTGAACTGGATGTAGATTT
CATTGCTGCTTCGTTTATTCGTAAAGCTTCCGATGTATTAGAGATTAAGCGTATTTTAGAAAAAGATGATGCTGATATTA
AGATTATATCTAAGATAGAAAGTGAAGAAGGCGTCGAAAATATTGATGAAATTATTGAAGTTTCTAGTGGAATTATGGTT
GCTCGGGGTGATCTAGGAGTTGAAATTCCTACAGAACAGGTTCCAGCAGCCCAAAAGATGATGATTGATAAATGTAATAG
GGAAGGTAAGCCGGTAATTACTGCTACTCAGATGCTTGATTCTATGATTCGAAATCCCCGACCGACTAGGGCAGAAGCAA
GTGATGTAGCTAATGCTATTTTAGATGGAACTGATGCTACAATGTTATCAGGAGAGACAGCAATGGGAGAGTATCCTGTA
AGATCAGTAGAAACTATGGCCAAGATTGCTCAAGAAATCGAAGAATCTGAACAGTATGCTAAACAGATGGCACAGAAGAA
TATGGTGCCGCCGCGGACAGTTACAGATTCAATTAGCTATTCAACCTGTGAAACTGCTCATGATTTAGGAGCCTCGGCGA
TTATTACTTCTACCAGCTCTGGGCATACTGCCCGTATGGTTTCTAAATACCGTCCTTATTCTCCAGTAATTGCAGCTACA
CCAAATCCTAAAGTCTGTAAACAGTTAGCTTTATCCTGGGGAGTTAAGCCTATTGTAGTAGAAGATACTGCTTCTACTGA
TGATATGTTTGAAGTTTCAGTTCGGGGAGCTTTAGAGGCTGGATATATTAATATGGGCGATTTAATTGTCTTGACCGCTG
GAACTCCTGTTGGTGTATCCGGTACTACTAATCTACTTAGGGTGCATATTGTCGGAGAAGCTATTGTACGAGGGACGGGA
ATCGGCAAGACTGCTTTCAGTGGACGAGTCTGTATTGTAGATGATCCTGATGAAGCTAACGAGAAGATGAAAGAAGGAGA
TGTATTAGTTACTCATAGTACTGATAGAGACTTTGTACCAGCAATGAAGAAAGCAGAAGCTGTAATTACTGAAGAGGCTG
GTCTTACTTCTCATGCTGCTATCGTTAGTTTAAACTTAGGTATTCCGGCAGTAGTAGGTGCTTATGATGCTATGGAAATG
TTAGAGGATGGGGAGCTGGTAACTGTCGATAGCGTCCGCGGTTTAGTATATAAAGGAGAAGCCAATGTTTTGTAA

Protein sequence :
MRRTKIVCTIGPGSDDEETLSQLIDAGMNVARMNFSHGNHQEHKERIQRVRNLAAQKGKPVAIMLDTKGPEVRTGMLKND
EEVTLKEGEKFVLTTEEIEGDDKRVSVSYNDLPKDVEVGGTILIDDGLIELEIDNISDTEVECTVLNGGQLGLRKGVNLP
GVSVNLPAITDKDAADIKFGIELDVDFIAASFIRKASDVLEIKRILEKDDADIKIISKIESEEGVENIDEIIEVSSGIMV
ARGDLGVEIPTEQVPAAQKMMIDKCNREGKPVITATQMLDSMIRNPRPTRAEASDVANAILDGTDATMLSGETAMGEYPV
RSVETMAKIAQEIEESEQYAKQMAQKNMVPPRTVTDSISYSTCETAHDLGASAIITSTSSGHTARMVSKYRPYSPVIAAT
PNPKVCKQLALSWGVKPIVVEDTASTDDMFEVSVRGALEAGYINMGDLIVLTAGTPVGVSGTTNLLRVHIVGEAIVRGTG
IGKTAFSGRVCIVDDPDEANEKMKEGDVLVTHSTDRDFVPAMKKAEAVITEEAGLTSHAAIVSLNLGIPAVVGAYDAMEM
LEDGELVTVDSVRGLVYKGEANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-95 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-95 52
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-95 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-94 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acear_1860 YP_003828428.1 pyruvate kinase VFG0479 Protein 3e-95 52