Gene Information

Name : Acear_1643 (Acear_1643)
Accession : YP_003828213.1
Strain : Acetohalobium arabaticum DSM 5501
Genome accession: NC_014378
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1738617 - 1739936 bp
Length : 1320 bp
Strand : -
Note : COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterProIPR005714:IPR013380:IPR020005:IPR004100:IPR 000194:IPR003593:IPR020003; KEGG: hmo:HM1_2224 flagellar protein export ATPase FliI, PFAM: H+transporting two-sector ATPase alpha/b

DNA sequence :
ATGAGCGATAAGCTATTAGACGGTAATAAGTTAGCAAAGGAACTGGAGTCCTGGTCGCTGGTGAATAACTTTGGTAAGAT
CAGTCAGGTTGTAGGTTTGATTATTGAATCAGAAGGTCCTGATGTAACATTAGGGGAGATCTGTCTGATTAAATCAGATT
CCAATTCTGAACCGATTCAGGCTGAAGTAGTAGGTTTTAGAGATAATAAAGTTTTACTAATGCCTTTAGGAGAAATGGGC
GGTATTGGACCGGGCTGTAAAGTAGAAGCTACTAATGAACCGCTTAAGGTTAAAGTAGGTGATGAGTTATTAGGCCATGT
TTTAGATGGATTAGGTAATCCATTGACAGATCTGGATCTGGACCAATTACATAAAGAGTACTCAGTAAATAATCCCCCCC
CTAATCCTTTAGTGCGCCAGAGAATAACTGAACCGCTATCAGTAGGCATTAGGAGTATAGATGGCCTCTTGACCTGCGGG
CGCGGCCAGCGATTAGGTATCTTTGCCGGTAGCGGAGTTGGTAAAAGTACATTATTGGGTATGATTGCCCGCAATACAGC
TGCAGATGTAAATGTAATCGGTTTGATCGGAGAGCGAGGCCGTGAGGTTAGAGAATTTATTGAAGATGATTTAGGAACGG
AAGGTCTTAAGCGTTCAGTAGTGGTAGTAGCTACTTCCGATCAACCGGCTTTAGTCAGACTGAAAGGTGCTTTAGTAACT
ACTACTATTGCTGAATACTTTCGCGATCAGGGACAAGATGTAATGCTGATGATGGATTCAATCACAAGATTTGCCAGAGC
CCAAAGAGAGGTTGGACTAGCTGTAGGTGAACCTCCAGCAACTAGAGGCTATACTCCTTCTGTATTTGCTATGCTGCCTA
AATTACTAGAACGGGCAGGAAATAATGAAGTAGGAACAATTACTGGGCTGTATAATGTCTTAGTTGAAGGCGATGATATG
AATGAACCGATTGCGGATGCTGTACGGGGGATTGTTGACGGCCATATTACTCTAAGTAGGGACTTAGCTACTCAGAATCA
CTATCCTGCTGTTGATGTGTTAGAGAGTGTCAGCCGGGTGATGGATGATGTTGTCACTGAAGAACATCAGACTGCAGCCC
AACAGTTAAGAGAAGTGCTGGCTACCTATGAAGAGTCCAAGGATTTAGTCAATATTGGTGCCTATGAAGAAGGGAATAAT
CCGGAACTGGATTATGCTCTAAGTAAGTTAGATGAAGTAAATGATTTCTTGCAGCAGGGAGTTGAGGAAAAGTCTGATTT
TGAAACTACCCTTCAGCAATTGAAAAACATCTTCAAATAA

Protein sequence :
MSDKLLDGNKLAKELESWSLVNNFGKISQVVGLIIESEGPDVTLGEICLIKSDSNSEPIQAEVVGFRDNKVLLMPLGEMG
GIGPGCKVEATNEPLKVKVGDELLGHVLDGLGNPLTDLDLDQLHKEYSVNNPPPNPLVRQRITEPLSVGIRSIDGLLTCG
RGQRLGIFAGSGVGKSTLLGMIARNTAADVNVIGLIGERGREVREFIEDDLGTEGLKRSVVVVATSDQPALVRLKGALVT
TTIAEYFRDQGQDVMLMMDSITRFARAQREVGLAVGEPPATRGYTPSVFAMLPKLLERAGNNEVGTITGLYNVLVEGDDM
NEPIADAVRGIVDGHITLSRDLATQNHYPAVDVLESVSRVMDDVVTEEHQTAAQQLREVLATYEESKDLVNIGAYEEGNN
PELDYALSKLDEVNDFLQQGVEEKSDFETTLQQLKNIFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-115 56
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-105 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-106 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-106 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-106 51
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-103 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-103 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-103 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-104 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-103 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 6e-90 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-90 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-90 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-90 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-90 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-93 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-93 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-93 49
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-92 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-92 49
escN AAK26715.1 EscN Virulence LEE Protein 4e-92 49
escN AAL57542.1 EscN Virulence LEE Protein 4e-92 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-92 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-91 49
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-93 49
escN AAC38383.1 EscN Virulence LEE Protein 1e-91 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-91 49
escN AAC31513.1 L0034 Virulence LEE Protein 8e-92 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-92 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-92 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-92 49
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-92 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-84 47
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-84 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-84 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-77 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-88 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-80 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-77 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-78 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-79 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-79 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 4e-81 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-77 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 9e-77 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-77 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-77 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-78 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-76 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-76 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 3e-121 56
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 5e-114 55
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 1e-114 55
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 1e-113 55
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 7e-106 52
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 1e-90 49
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 5e-92 49
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 8e-92 49
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 9e-101 48
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 1e-97 48
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 4e-77 44
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 5e-86 43
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 3e-77 43
Acear_1643 YP_003828213.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 3e-82 43