Gene Information

Name : Toce_0353 (Toce_0353)
Accession : YP_003824757.1
Strain : Thermosediminibacter oceani DSM 16646
Genome accession: NC_014377
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 353958 - 355493 bp
Length : 1536 bp
Strand : +
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926:IPR004739:IPR001674:IPR000991:IPR 011702:IPR006220; KEGG: mta:Moth_2105 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase [glutami

DNA sequence :
ATGATTAAAGACCAGGAAAACGTGATCGTTCTCGATTTCGGCGGGCAGTACAGCCAGCTGATAGCTCGCCGGGTCAGGGA
AGCAAGTATTTATTGCGAGATTCTGCCCTACAATACCCCTATGGACGAAATTTTAAAGAGAAAGCCGAAAGCCATAGTTT
TCTCCGGCGGCCCGGCCAGCGTATACTCGGAAAATGCGCCGGTATGCGATAAGAGGATTTTCGATACCGGCATACCAATC
CTGGGAATCTGCTACGGTATGCAGCTCATGTGCCATATGCTGGGTGGAAGGGTTGAACCGGCCGAAACAGCCGAGTACGG
CAGGGCCGAACTTGTGGTTGAAGAGGAGGACGGTATATTCAGCGGTTTGGAAAAAAACCTTACCGTCTGGATGAGCCACG
GGGATTCCATAATAACGCTGCCCGAAGGATTCAGGACATTGGCGCGCACGAAAAACACCCCCCATGCGGCTATCGGTAAC
GGCAGGAACCTCTTCGGGGTGCAGTTTCACCCGGAGGTCGTCCATACGCCCAGGGGCAGGGAAATTCTCAACAATTTCCT
CTTCGGCATAGCCGGCTGTACCGGGACCTGGTCCATGAAAACCTTTGTCGAGGAACAGATCAGGCTGATCAGGGAAAGGG
TGGGTAACGGAAGAGCCCTCTGCGCCCTGAGCGGCGGGGTGGATTCTTCGGTGGCTGCGGTGATCACCCACAGGGCCCTG
GGGGATAACCTGACCTGTATTTTCGTGGACCACGGCCTTTTGCGAAAAGACGAAGCCAGGAAGGTTATAGAGACTTTTAA
AGACAAGTTCCATATAAACCTGATTGCCGTTGATGCATCCGACAGGTTTTTAAAAAGGCTGGAAGGTGTTACAGACCCGG
AGGCGAAGCGCAGGATTATCGGTGAAGAATTCATCAGGGTATTCGAAGACGAGGCTAAGAAACTGGGAAAGATCGACTTT
CTGGTTCAGGGGACCCTATACCCCGATGTCATTGAAAGCGGTACCCAGACGGCGGCGGTTATAAAAACCCACCACAACGT
GGGCGGACTTCCCCAGGACCTCAATTTCGAGCTCATCGAACCCCTTCGGGACCTATTCAAGGACGAGGTCAGAAAGGTGG
GACTCCAGCTGGGACTACCCGAGGAAATCGTGTACCGCCAGCCCTTCCCGGGACCAGGGCTTGCTGTGAGGGTTCTGGGT
GAAGTGACCCGCGAGAAACTTTCTATCCTGCGGGAAGCCGATGCTATAGTGACCGAAGAAGTAAAAAAAGCCGGACTTGA
CAGGGAGCTCTGGCAGGCCTTTGCGGTGCTCACCGACGTAAAGAGCGTGGGAGTGATGGGTGACGAGAGGACTTACGCAT
ACACGGTGGCGATCCGGGCCGTCACGAGCGAAGACGGCATGACGGCCGACTGGGCCAGGCTTCCGTACGACCTGCTGGAT
AATATGTCTACCAGGATCGTAAACGAAGTTCCCGGGGTCAACAGGGTCGTTTACGACATAACCTCAAAACCGCCGGCTAC
CATCGAATGGGAATAA

Protein sequence :
MIKDQENVIVLDFGGQYSQLIARRVREASIYCEILPYNTPMDEILKRKPKAIVFSGGPASVYSENAPVCDKRIFDTGIPI
LGICYGMQLMCHMLGGRVEPAETAEYGRAELVVEEEDGIFSGLEKNLTVWMSHGDSIITLPEGFRTLARTKNTPHAAIGN
GRNLFGVQFHPEVVHTPRGREILNNFLFGIAGCTGTWSMKTFVEEQIRLIRERVGNGRALCALSGGVDSSVAAVITHRAL
GDNLTCIFVDHGLLRKDEARKVIETFKDKFHINLIAVDASDRFLKRLEGVTDPEAKRRIIGEEFIRVFEDEAKKLGKIDF
LVQGTLYPDVIESGTQTAAVIKTHHNVGGLPQDLNFELIEPLRDLFKDEVRKVGLQLGLPEEIVYRQPFPGPGLAVRVLG
EVTREKLSILREADAIVTEEVKKAGLDRELWQAFAVLTDVKSVGVMGDERTYAYTVAIRAVTSEDGMTADWARLPYDLLD
NMSTRIVNEVPGVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-155 59
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-155 59
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-155 59
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-139 55