Gene Information

Name : Toce_0320 (Toce_0320)
Accession : YP_003824724.1
Strain : Thermosediminibacter oceani DSM 16646
Genome accession: NC_014377
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 314613 - 315512 bp
Length : 900 bp
Strand : +
Note : COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: dal:Dalk_4010 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; PRIAM: Hydroxymethylbilane synthase; SPTR: Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; manually

DNA sequence : 
GTGATACCAACGGGTAGGATTGTGAGGGTAGGGAGCAGGGAGAGCAGGTTGGCCCTGGTCCAGACCGAAATAGTCATAAG
GTTGTTAAAGGATCGCCGTCCCGAACTGGAATTCGAAGTCGTTAAAATTAAGACGCAGGGCGATAAACTGCTGGATGTAA
ATTTGAGCGATGCGGGAGGCAAGGGGGTTTTCGTAAAGGAGATAGAAGAGGCGCTCCTCGCCGGATCGATAGACCTGGCC
GTTCACAGCATGAAGGACGTGCCCTACGAGCTTCCCGAAGGTTTGTGCATAGCGGCGGTAACGGAAAGGGAAGACCCCAG
AGATGTGCTCATATCGAGAGACAAGAGAAGACTTTTGAACCTGAGGCCCGGGGCGAGGATCGGGACGTCCAGCCTGAGGC
GGTCGGTACAGCTCAAAGCCCTCAGGCCCGATCTAGACATTGTGCCGGTCAGGGGCAACGTCCCGACCAGAATCCGGAAA
ATGGATGACCTGGAACTGGACGGTTTGGTGCTGGCGGCCGCAGGCATAAAGAGGCTCGGCCTGGAGGAACTTATCGCGGA
GTATTTTCCACCGGAGGTGATAGTGCCCGCTGTGGGCCAGGGAGCGCTGGCGGTGGAAGCCAGGAAGGACGACGATATAT
TGGAATTGGCCGGGCTTGTGAGCCACAAAGCAACCGAGGTTGCCGTGAGGGCGGAAAGATCCTTCATGAGGGCCCTGGGG
GGAAGCTGCCGGGTGCCGCTGGGGGCCTTTGCGAGGGTGGAAGGGACGGTGGTGACCCTGGTAGGAATGGTGGAAAAAAA
CGGAAGCGTCTGCAAGGGCACGATGTCCGGAAAGTTAAAAGAAGCCGAAGAAATCGGGCTGAGACTTGCAGAAAGGCTGG
GTGATAGCAGTGACCGGTAA

Protein sequence : 
MIPTGRIVRVGSRESRLALVQTEIVIRLLKDRRPELEFEVVKIKTQGDKLLDVNLSDAGGKGVFVKEIEEALLAGSIDLA
VHSMKDVPYELPEGLCIAAVTEREDPRDVLISRDKRRLLNLRPGARIGTSSLRRSVQLKALRPDLDIVPVRGNVPTRIRK
MDDLELDGLVLAAAGIKRLGLEELIAEYFPPEVIVPAVGQGALAVEARKDDDILELAGLVSHKATEVAVRAERSFMRALG
GSCRVPLGAFARVEGTVVTLVGMVEKNGSVCKGTMSGKLKEAEEIGLRLAERLGDSSDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-54 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-54 46