Gene Information

Name : Toce_2251 (Toce_2251)
Accession : YP_003826583.1
Strain : Thermosediminibacter oceani DSM 16646
Genome accession: NC_014377
Putative virulence/resistance : Unknown
Product : primary replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 2251668 - 2253023 bp
Length : 1356 bp
Strand : -
Note : COGs: COG0305 Replicative DNA helicase; InterPro IPR007694:IPR007692:IPR007693; KEGG: tte:TTE2774 replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SPTR: Replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB-li

DNA sequence :
ATGAATTTGATGCCTCCAAAAGTGCCTCCTCATAACATGGAAGCCGAACAGTCGGTTTTGGGTTCCATGCTTCTTTCCAG
GGAGGCTATTTACGTGGCGCTGGAACGCCTGAAAAGCGAAGACTTTTATATAGAGGCTCACCGCAGAATATTCGATATCA
TTGCCGAGCTCCACGAGAACAGGGACCCCGTCGACCTTATAACCGTTACCGAAGCCCTGCGCAGCAGAAAGATGCTGGAA
GAAGTGGGTGGGGTCACATACCTTACCAACCTTACCGAAGTGGTACCTACACCCGCCAACATAGCCCAGTACTGCAAGAT
CGTCGAGGAAAAGGCCCTGCTGCGTCGCCTAATCGAGACCGCCTCCAAGATACTGTCGCTGGCTTACGAGCCGAAGGATG
ACGTGGAGGAGCTGCTGGACGAAGCCGAGAGAAGGATATTCGGCATAGTTCAAAAGCGCCGGGTGGATAACTTCCACCAT
ATAAAAGACGTGCTGCTTGCCACCTTCGAGCGCATAGAGCAGCTCTACAATTCAAAGGGAGGAATAACCGGGGTGCCCAC
CGGCTTCCCCGACCTGGACGCAATGACTTCCGGACTGCAACCCTCGGACCTCATACTTGTGGCTGCAAGGCCCAGTATGG
GCAAGACCGCCTTTGCTCTGAACATAGCCCAGAACGCAGCCATAAGACACCGCATCCCGGTGGCCATTTTCAGCCTGGAA
ATGTCCAAAGAGCAGCTGGTGCAGAGAATGCTCTGCGCCGAATCCAACGTGGACAGCCACAAGCTGCGCACCGGAAGGCT
TGAAGAGGACGACTGGCCAAGACTAGCCCGGGCTATGGGTCCGCTATCGGAAGCCCCTATCTACATAGACGACACCCCGG
GCATCACCTGCCTGGAGATCAGAGCCAAGGCGAGAAGGCTCAAAGCTGAAAAGGGACTGGGGCTCGTGGTGATCGACTAC
CTGCAGCTCATAGCGGGAAGGGGGCAGTCGGAAAACCGGCAGCAGGAGATTTCGGAGATCTCCAGGTCCTTAAAAGCTCT
GGCAAGGGAGCTCAACGTCCCGGTGGTGGCGCTGTCCCAGCTTTCCAGAGCTCCGGATGTCAGGGCCGACCACCGGCCGG
TGCTCAGCGACCTTAGAGAATCGGGCAGCCAGGAGCAGGACTCGGACCTGGTGGCTTTCTTATACCGCGAGGATTACTAC
AATCCCGACACCGACAGGAAGAACATCGCCGAAGTCATCATAGCAAAACAGAGAAACGGCCCGACGGGCAAAGTAGAGCT
GGTATGGCTCTCCCAGTACACCAAGTTCGTGAGCATTGAAAAACACCGCCAGAGCGAGGCGGCCAAGTATGCATAA

Protein sequence :
MNLMPPKVPPHNMEAEQSVLGSMLLSREAIYVALERLKSEDFYIEAHRRIFDIIAELHENRDPVDLITVTEALRSRKMLE
EVGGVTYLTNLTEVVPTPANIAQYCKIVEEKALLRRLIETASKILSLAYEPKDDVEELLDEAERRIFGIVQKRRVDNFHH
IKDVLLATFERIEQLYNSKGGITGVPTGFPDLDAMTSGLQPSDLILVAARPSMGKTAFALNIAQNAAIRHRIPVAIFSLE
MSKEQLVQRMLCAESNVDSHKLRTGRLEEDDWPRLARAMGPLSEAPIYIDDTPGITCLEIRAKARRLKAEKGLGLVVIDY
LQLIAGRGQSENRQQEISEISRSLKALARELNVPVVALSQLSRAPDVRADHRPVLSDLRESGSQEQDSDLVAFLYREDYY
NPDTDRKNIAEVIIAKQRNGPTGKVELVWLSQYTKFVSIEKHRQSEAAKYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-72 45
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-78 43
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 2e-70 42
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 4e-70 42
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 3e-72 41
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 3e-65 41
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 3e-65 41