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Name : Closa_3709 (Closa_3709) Accession : YP_003823852.1 Strain : Clostridium saccharolyticum WM1 Genome accession: NC_014376 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : - Position : 4022335 - 4024413 bp Length : 2079 bp Strand : - Note : TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; KEGG: efa:EF2312 DNA topoisomerase III; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein DNA sequence : ATGAAGCTTGTATTAGCGGAAAAGCCCTCGGTAGCCATGAGCCTCTCGAAGGTAATCGGAGCAAATCAGCGCGGGGATGG TTATATGGAGGGCAATGGCTACATTGTCAGCTGGTGTGTGGGGCATCTGGTGGAACTTTCCCAGCCGGAAGCCTATGATG AGAAGTATGCCAAGTGGAGGTATGATGACCTTCCGATTTTGCCGGAACATTGGCAGTATCAGGTGTCCACCAGTACGAAA AAGCAGTTTGGAATCCTGAAAAAGCTCATGCTGCGGAAGGATGTAAAGAGTCTGATCTGTGCAACCGATGCAGGCCGTGA GGGAGAACTGATTTTCCGACTGGTTTACCATCAGTGCGGCTGCAAAAAGCCGGTGGAACGACTTTGGATTTCCTCGATGG AGGACAGTGCTATCCGGGAAGGCTTTCAGAAGCTCAGACCGGGAACAGAATATGATGCCTTATATGAGGCGGCTTTATGC CGGGAGCGTGCCGACTGGATTGTCGGAATCAACGCCACCCGGCTTTTTTCATGTCTGTATGGGCAGACCCTGAATGTGGG GCGCGTGATGACACCAACCCTTGCGATGGTGGTCATGCGGGATGCAGCAATCCGGGCGTTCAAACCTGAGCCGTTCTACT CGGCAGAATTAAAATTTCGGGATTTTCAAGCGGGTGGTGAGCGGATGAAAGAAAAAGCAGAAGCAGAAAAACTGGTGGCA GAGTGCTGTCAGGCAGGTAGTGCCATCATTACCAAGGTGGAGCAGAAAGAAAAATCAGAGAAGCCCCCAGCTCTCTTTGA TCTGACATCGCTTCAGCGAGAAGCAAACCGGCAGCTGGGATTTACTGCCCAGCAGACCCTGGATTACACACAGGCTCTGT ACGAGAAGAAACTCGTAACCTATCCCCGTACCGACAGCCGGTATCTGACGGATGATATGGCACCGTTGGTGCCGGAACTT GTCTCTGTGATCCAGCAGAGCTTTCAGATTCAGCCGGATGTGCCGGCACCGGTGAATGCAGCGCAGGTCATCAATTCTAA GAAAGTTACCGATCACCATGCCATTATTCCTACAAAAACAGCGGCAGGTCATGACATTTCCTCTCTTCCCAGTGGAGAAC AGGCGATTCTTATCATGCTGGCGGTGCGGCTGATTTGTGCGGTAGGAACTCCCTGCCGCTATGCAGAAACCATAGTAGAA GCCGAGTGCGCCGGTCAGAAGTTCCGTACAAAAGGCAAAACGGTCACGGATATGGGCTGGAGACAGTATGCAGGAAGGTC GAGTGAGGATGCTGAGAAGAATGCGGAGGCGTGTAATCTGCCGGAGCTTTCGGAAGGCATGACACTGGAACTTGCTGGTG TCGATCTGAAAGAGGGTAAGACCAGCCCACCCAAGAGGTTTACCGAAGATCTTCTGCTTTCAGCGATGGAGAGTGCCAGC TCGGATGAATTCCCGGCTGGCGTAGAGCGAAAAGGCATCGGCACACCGGCCACACGCGCTGCCATCATCGAAAAACTGGT GCAGAAAGGCTTTATCGAGCGCAGGGGTGATAAGAAAACGAAATACCTTTGTTCTACGGACAAGGGAAATGCGCTGGTGA CGGTGGTGCCGGAACAGATTCAGTCTCCATCCATGACGGCAGACTGGGAGGAAAAACTGCTGAAAATAGAACATGGCGAG TATGACAGCGATGCCTTTATGGGAGAAATCAGCAGCATGGTCAATGGACTTGTTAAAACCTACGAGGCTGTAAAAGGAGC CGATGTGCTGATGCAGCCGGAGCGCAAGGTCATTGGTTCCTGCCCGGCCTGCGGCAGTGATGTCTGTGAAACGGTAAAGG GATGGTTTTGCAGGGATAAGAGCTGTAAATTTGCGCTCTGGAAGGAAAACAGGTTCTTTCAGACACTGGGAAAGCAGATG ACAGAGGAACTGGCAAAGCAACTGGTAAATCAGGGAAAAGCACGGCTTACCCATTGCTATTCCAGGAAGTCCAATCGTTA CTATGACACAACCGTTCGTGTAGAGACCGGCGAGGACGGTGCAGCAGCTTTTAAGCTGGAGTTTGGAGGTAAAAAATGA Protein sequence : MKLVLAEKPSVAMSLSKVIGANQRGDGYMEGNGYIVSWCVGHLVELSQPEAYDEKYAKWRYDDLPILPEHWQYQVSTSTK KQFGILKKLMLRKDVKSLICATDAGREGELIFRLVYHQCGCKKPVERLWISSMEDSAIREGFQKLRPGTEYDALYEAALC RERADWIVGINATRLFSCLYGQTLNVGRVMTPTLAMVVMRDAAIRAFKPEPFYSAELKFRDFQAGGERMKEKAEAEKLVA ECCQAGSAIITKVEQKEKSEKPPALFDLTSLQREANRQLGFTAQQTLDYTQALYEKKLVTYPRTDSRYLTDDMAPLVPEL VSVIQQSFQIQPDVPAPVNAAQVINSKKVTDHHAIIPTKTAAGHDISSLPSGEQAILIMLAVRLICAVGTPCRYAETIVE AECAGQKFRTKGKTVTDMGWRQYAGRSSEDAEKNAEACNLPELSEGMTLELAGVDLKEGKTSPPKRFTEDLLLSAMESAS SDEFPAGVERKGIGTPATRAAIIEKLVQKGFIERRGDKKTKYLCSTDKGNALVTVVPEQIQSPSMTADWEEKLLKIEHGE YDSDAFMGEISSMVNGLVKTYEAVKGADVLMQPERKVIGSCPACGSDVCETVKGWFCRDKSCKFALWKENRFFQTLGKQM TEELAKQLVNQGKARLTHCYSRKSNRYYDTTVRVETGEDGAAAFKLEFGGKK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB-2 | NP_815968.1 | DNA topoisomerase III | Not tested | Not named | Protein | 0.0 | 54 |
| EFAU085_00720 | YP_008394244.1 | DNA topoisomerase III | Not tested | Not named | Protein | 6e-165 | 49 |
