Gene Information

Name : Closa_2953 (Closa_2953)
Accession : YP_003823110.1
Strain : Clostridium saccharolyticum WM1
Genome accession: NC_014376
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3180351 - 3181892 bp
Length : 1542 bp
Strand : -
Note : KEGG: cbt:CLH_0377 GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I

DNA sequence :
GTGAAGAGAGAAATGATTATCGTTCTGGATTTCGGCGGACAATACAATCAGTTGATTGCCAGAAGGGTCAGAGAATGCAA
CGTTTACTGTGAGGTCCATCCCTACACGCTGTCATTGGAAAAGATTAAGGAAATGAATCCCAAAGGAATCATTTTTACAG
GTGGCCCAAACAGCGTATATAAGGAGGAGTCCCCTCGCTGTGAGAAGGAAATCTTTGATATGGGAATCCCGATTCTGGGA
ATCTGCTATGGTTCTCAGTTAATGGCATATATGCTGGACGGCAAGGTTGCCACAGCACCTGTCAGTGAATACGGAAAGAC
GGAAGTTGACGTGAAGGCTGACAGTAAGATTTTAGAAAAGGTAAGTTCCAAGACCGTCTGCTGGATGAGTCATACGGATT
ATATTGAGGAGGCTCCGGAAGGATTCCGCATCACAGCCCATACTCCCGTTTGCCCGGTTGCCGGTATGGAATGGGAGGAG
CGGGGCCTTTATGCAGTACAGTTCCATCCTGAAGTTATGCATACCCAGGAAGGTGTTAAGATGCTTTCCAATTTTGTATA
TAATGTCTGCAAGTGTTCCGGTGACTGGAAGATGGATTCCTTTGTGGAGTCTTCCATTGCAACCATCAGGGAAAAGGTTG
GAGACGGCAAGGTGCTATGTGCTTTATCCGGCGGAGTAGATTCTTCCGTAGCTGCCGTTATGCTGGCCAAAGCGGTGGGA
AAGCAGCTGACCTGTGTGTTTGTTGACCACGGCCTTTTACGTAAAAACGAGGGAGACGAGGTAGAAGCTGTATTTGGACC
GGCTGGGCCTTATGATTTGAATTTTATCCGCGTGAATGCTCAGGACCGTTTTTATGGCAAGCTGGCAGGTGTGGAAGATC
CTGAAACCAAACGTAAGATCATTGGCGAAGAATTTATCCGCGTCTTCGAGGATGAGGCGAAGAAAATCGGAAAAGTGGAT
TTCTTTGTACAAGGAACCATTTATCCGGACGTAATCGAATCCGGTCTTGGAAAGTCAGCGGTGATCAAGTCCCATCACAA
TGTGGGAGGACTCCCTGAGCATGTGGATTTTAAAGAGATCATTGAGCCTTTGAGACTTCTTTTTAAGGATGAAGTACGGA
AGGCGGGCCTGGAGCTGGGCATTCCGGAGTATCTGGTTTACCGTCAGCCGTTTCCGGGTCCTGGACTTGGGGTCAGGATC
ATAGGTGCTGTCACTCCTGAGAAGGTAAGGATCGTTCAGGAGGCGGATGCCATTTACAGAGAAGAGATTGCCAAGGCTGG
TGTTGATAAAGGACTGGGACAGTATTTTGCGGCATTGACCAATATGCGCTCTGTTGGCTGCATGGGAGATGAAAGAACTT
ATGATTATGCCATTGCCTTAAGAGCGGTGCTTACCTCTGACTTTATGACGGCTGAATCGGCAGAACTGCCCTGGGAAGTA
TTGGGGACAGTGACCAGAAGGATTGTGAATGAAGTAAAAGGCGTGAACCGGGTGCTTTATGATTGTACTGGGAAGCCGCC
GGCTACGATTGAATTTGAATAG

Protein sequence :
MKREMIIVLDFGGQYNQLIARRVRECNVYCEVHPYTLSLEKIKEMNPKGIIFTGGPNSVYKEESPRCEKEIFDMGIPILG
ICYGSQLMAYMLDGKVATAPVSEYGKTEVDVKADSKILEKVSSKTVCWMSHTDYIEEAPEGFRITAHTPVCPVAGMEWEE
RGLYAVQFHPEVMHTQEGVKMLSNFVYNVCKCSGDWKMDSFVESSIATIREKVGDGKVLCALSGGVDSSVAAVMLAKAVG
KQLTCVFVDHGLLRKNEGDEVEAVFGPAGPYDLNFIRVNAQDRFYGKLAGVEDPETKRKIIGEEFIRVFEDEAKKIGKVD
FFVQGTIYPDVIESGLGKSAVIKSHHNVGGLPEHVDFKEIIEPLRLLFKDEVRKAGLELGIPEYLVYRQPFPGPGLGVRI
IGAVTPEKVRIVQEADAIYREEIAKAGVDKGLGQYFAALTNMRSVGCMGDERTYDYAIALRAVLTSDFMTAESAELPWEV
LGTVTRRIVNEVKGVNRVLYDCTGKPPATIEFE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-143 58
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-143 58
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-143 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-119 50