Gene Information

Name : Closa_2701 (Closa_2701)
Accession : YP_003822882.1
Strain : Clostridium saccharolyticum WM1
Genome accession: NC_014376
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4845
EC number : 2.3.1.28
Position : 2931563 - 2932195 bp
Length : 633 bp
Strand : +
Note : KEGG: ssb:SSUBM407_0980 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase

DNA sequence : 
ATGTTTCAAAAAATTGACCGCTCCACATGGAAGCGTGAGGAATATTTTAACCATTACTTTTCCAATCTACCTTGTACCTA
CAGCATGACGTTGCAGCTTGATATAACTATTTTACGGAAGAAAAATTTGAGTCTATATCCAACCATGCTTTATCTTATTA
CAAGTGTCGTCAATCGTCATGAGGAATTTCGTACAGCATTGGACAATAGCGGAGATGTAGGCGTATACGATTATCTTTCT
CCTTGTTATACGGTCTTTCACAAAGAAAGCGAAACCTTCTCTAACCTATGGACAACATATAGTCCTGACTATGAAAAGTT
TTGTGCAGATTACAAAAAGGATATTCAGGAATATGGCTCTATTGATCGTATGATAGCCAAGCCTCATGCCCCGGAAAACA
CCTTTCCAGTATCTATGATTCCATGGTCGAGCTTCGATGGTTTTAACCTCAATCTACAAAAAGGGTATGACTATTTATTA
CCAATTATCACAATGGGTAAGTTTAAGGTTGTAAATGGGCGATACTTTTTACCACTTGCTGTGCAAGTGCATCATGCTGT
TTGCGATGGGTTTCATCTGTCACGGTTTTTCAATGAACTACAAGAACTGATTGAACAATTCCTCAAAAATTAA

Protein sequence : 
MFQKIDRSTWKREEYFNHYFSNLPCTYSMTLQLDITILRKKNLSLYPTMLYLITSVVNRHEEFRTALDNSGDVGVYDYLS
PCYTVFHKESETFSNLWTTYSPDYEKFCADYKKDIQEYGSIDRMIAKPHAPENTFPVSMIPWSSFDGFNLNLQKGYDYLL
PIITMGKFKVVNGRYFLPLAVQVHHAVCDGFHLSRFFNELQELIEQFLKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catA2 ACF06176.1 chloramphenicol acetyltransferase II Not tested Tn5036-like Protein 5e-39 46
cat YP_006098370.1 chloramphenicol acetyltransferase Not tested Tn2411 Protein 3e-35 41
cat CAJ77070.1 Chloramphenicol acetyltransferase Not tested AbaR1 Protein 2e-35 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase NC_010111.5787932.p0 Protein 1e-44 45
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase CP001581.1.gene2168. Protein 3e-47 45
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase NC_010426.6155849.p0 Protein 7e-38 43
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase NC_010427.6155852.p0 Protein 7e-38 43
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase CP004022.1.gene799.p Protein 9e-35 42
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase NC_010558.1.6276004. Protein 1e-35 41
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase NC_010410.6002590.p0 Protein 1e-35 41
Closa_2701 YP_003822882.1 chloramphenicol O-acetyltransferase NC_011586.7045194.p0 Protein 1e-35 41