Gene Information

Name : Closa_2682 (Closa_2682)
Accession : YP_003822864.1
Strain : Clostridium saccharolyticum WM1
Genome accession: NC_014376
Putative virulence/resistance : Resistance
Product : arsenite-activated ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 2917257 - 2918993 bp
Length : 1737 bp
Strand : -
Note : KEGG: dsy:DSY4598 hypothetical protein; TIGRFAM: arsenite-activated ATPase ArsA

DNA sequence :
GTGCAGTTATTTGATTTAAATAAGGTCCAATTAACAAAATACCTCTTTTTTACAGGCAAAGGCGGTGTTGGGAAAACATC
AACAGCCTGTGCGTCTGCAGTAACCCTTGCAGATCTTGGTAAAAAGGTGTTGCTCGTTAGTACAGATCCGGCTTCCAATT
TACAGGATGTGTTCCGTATGGAACTGACTGGTAAAGGAACGCCGATTCGGGATGTCCCCGGACTTATGGTAGCGAATCTC
GATCCTCTGAAAGCTGCGGCAGATTATCGTGAGAGCGTGATGGCACCATACCGGGGGAAATTGCCGGAATCCGTTTTAAA
AAATATGGAAGAGCAGCTTTCCGGCTCCTGTACGGTTGAAATAGCAGCATTTAATGAATTTTCGAATTTTATAACGGATG
AAAAGGCTAAGGAAGAGTATGACCATATTATATTTGATACGGCACCCACCGGTCATACTCTCCGCATGCTGCAACTACCT
TCTGCATGGAGCAATTTTATCAGTGAAAGTACCCATGGTGCTTCCTGTCTTGGTCAGCTTTCCGGGTTGGAGAGCAGAAA
AGAAATATATAAAAAGGCAGTCAGCACCCTGGCAAGCGGTGATATGACAACCTTGCTTCTGGTTTCAAGGCCGGAAACTG
CACCGTTAAAAGAAGCTGTGCGTGCTGCGAAAGAACTTTCTGATATTGGTGTCAGTAATCAGATAATGATTGTAAATGGT
GTATTAAATTCCTATGATGATCCGATATCTGAGAGCCTGTATCAAAAGCAGCAAAAGGCATTGGTACAAATGCCGGAGGA
ACTGAAAAGGCTGAAGCAATATTATGTGCCGCTCCGCGCATATAATATTACCGGTTTGGAGAATGTACGGAATTTATTGG
TGAAAGATAATTTCAATTTAGTTCATGCGGAATTAAAAGCGCAAGATATACCAACTCTGAATCATGTGGTAGATGATTTA
TATGAAAGTGGTAAGAAGGTTATTTTTACTATGGGTAAAGGCGGAGTAGGCAAAACTACGATTGCTGCCGCGATTGCAAT
GGGATTGTCAGCGAAAGGGGTAAACGTACACTTGACAACCACGGATCCGGCAGCTCACCTGAAGTTTGTTATGGAAGATC
CTAGCGGAATCACAATGAGCCATATTAATGAGAAGGAAGAACTGCTCCGATATCAGCAGGAGGTCCTTGCAAAGGCAAGA
GAAACCTTGTCAGAGGATGATGTTGCTTATGTAGAAGAAGATTTACGATCCCCTTGTACTCAGGAGATTGCAGTTTTCCG
TGCCTTTGCCGAGATTGTTGAAAATGCAGAAGATCAGGTTGTGGTAATAGATACGGCACCCACCGGGCATACACTATTAC
TGTTGGACTCTACCCAAAGCTACCATAAGGAAGTAAAACGTACCCAGGGAGATATCCCGGAATCTGTAAAAAAGCTACTA
CCAAGACTTCGTAACGCAGAGGAAACAGAAGTAATTATTGTGACACTGGCAGAAACTACTCCTGTGTTTGAGGCAATGAG
ATTAGAGGAGGACTTGGAACGGGCTGAAATAACTGTTAAATGGTGGGTAATTAATTCTTCCCTTTATGCCACAGAAACCA
CGAACCGGCTGTTAAAGGCAAAAGCAAGCCATGAAATCCAATGGATCAATAAGGTAGATGATATTTCCAAGGGGAATTTT
GCGGTCATTCAGTGGAGTGCGGACGAAATTAAAGGAGAAAAATTACTTAGTATTTAA

Protein sequence :
MQLFDLNKVQLTKYLFFTGKGGVGKTSTACASAVTLADLGKKVLLVSTDPASNLQDVFRMELTGKGTPIRDVPGLMVANL
DPLKAAADYRESVMAPYRGKLPESVLKNMEEQLSGSCTVEIAAFNEFSNFITDEKAKEEYDHIIFDTAPTGHTLRMLQLP
SAWSNFISESTHGASCLGQLSGLESRKEIYKKAVSTLASGDMTTLLLVSRPETAPLKEAVRAAKELSDIGVSNQIMIVNG
VLNSYDDPISESLYQKQQKALVQMPEELKRLKQYYVPLRAYNITGLENVRNLLVKDNFNLVHAELKAQDIPTLNHVVDDL
YESGKKVIFTMGKGGVGKTTIAAAIAMGLSAKGVNVHLTTTDPAAHLKFVMEDPSGITMSHINEKEELLRYQQEVLAKAR
ETLSEDDVAYVEEDLRSPCTQEIAVFRAFAEIVENAEDQVVVIDTAPTGHTLLLLDSTQSYHKEVKRTQGDIPESVKKLL
PRLRNAEETEVIIVTLAETTPVFEAMRLEEDLERAEITVKWWVINSSLYATETTNRLLKAKASHEIQWINKVDDISKGNF
AVIQWSADEIKGEKLLSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 3e-126 48
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 9e-118 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Closa_2682 YP_003822864.1 arsenite-activated ATPase ArsA BAC0030 Protein 3e-117 47
Closa_2682 YP_003822864.1 arsenite-activated ATPase ArsA BAC0571 Protein 9e-118 46
Closa_2682 YP_003822864.1 arsenite-activated ATPase ArsA BAC0572 Protein 7e-116 46