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Name : Closa_1722 (Closa_1722) Accession : YP_003821941.1 Strain : Clostridium saccharolyticum WM1 Genome accession: NC_014376 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 1838603 - 1840090 bp Length : 1488 bp Strand : + Note : PFAM: Aldehyde Dehydrogenase; KEGG: dds:Ddes_1981 aldehyde dehydrogenase DNA sequence : TTGCAGAATGTAGAGCTTCTAAAGAAATATCAGTTATTCATAGGCGGGCAATGGAAGGATGCTTCCGATGGAAAAACATT TCCGACAATCTGCCCGGCCGATGGGAGGGTGCTGACTGAGTGCGCTGAGGCAACAAAGGATGACGTGGATGAGGCGGTCC GGGAAGCATGGAAGGCATTTGAAACCTGGAAGAATGTACCGGTAAACCAGAGAGCTGCCATTCTGAATAAGATTGCGGAT ATCATAGATGCGAATAAGGAACATCTTGCCATGGTGGAAACCCTGGACAACGGGAAACCCATAAGGGAAACCTTGACGGT GGATATACCTCTTGGTGCCCAGCATTTCCGCTATTTTGCAGGCTGTATTATGGCGGAAGAGGGCAGTGCCAGTATACTGG GAGAAAATATCTTAAGTCTGATCCTGAAAGAACCGATCGGCGTGGTTGGGCAGATCGTTCCCTGGAATTTCCCATTCCTG ATGGCAGCCTGGAAGCTGGCACCGGTACTGGCAAGCGGCTGCTGTTCCGTCTTTAAGACCTCCAGCACCACTTCTCTCAG CGTTCTGGAACTGGCAAGGCTAATCCAGGATGTGATCCCGGCCGGGGTGTTTAATGTGATTACCGGAGCGGGTTCCAAGT CCGGGCAATATATGTTGGAACATGAAGGATTCCGGAAGCTTGCATTTACCGGCTCAACGGAAGTCGGAAAGAACGTGGCC CTAGCAGCAGCGGAAAAGCTGATTCCGGCTACTTTGGAGCTGGGCGGCAAATCGGCTAATATTTACTTTGAGGACTGTGA TTGGGAGATGGCCATGGATGGCTTACAGCTGGGGATTCTCTTTAACCAGGGCCAGGTATGCTGTGCGGGTTCCAGGGTCT TTGTGCAGGAAAGCATTTACGATAAGTTTGTGGAAGAAGCGGTTAAACGGTTTAACCAGGTAAAGGTCGGTCTTCCGTGG GATGAACATACCCAGATGGGAAGTCAGATCAGCAAAGGGCATATGAAGGATATTTTAAGCTACATAGAGATTGGAAAATC AGAAGGAGCGGCAGTGCTTTGCGGCGGAGAGCAGATTCTGGAGGACGGACTGGAAAACGGAGCATTTTTAAGGCCTACGC TCCTTGGCAATGTGACAAATGACATGAGGGTGGCACAAGAAGAGATCTTCGGACCTGTGGCATGTATCATTAAGTTTAAG ACAGAGGATGAGGCCGTGGCTATGGCCAATGACAGCCAGTACGGACTGGGTGGAGCAGTATGGACCAGAGACATCAATCG GGCAATACGGGTTGCCAGAGCGGTGGAGACCGGACGTATGTGGGTTAATACCTATAATTCCATTCCTGAGGGAGCTCCTT TCGGGGGATACAAGACTTCGGGAATCGGCCGTGAGACACATAAGGTCATTCTGGAACACTACACCCAGACAAAGAATATC ATGATCAATTTAACTGAATCTCCTTCCGGTTTTTATCCGGTTAAATAA Protein sequence : MQNVELLKKYQLFIGGQWKDASDGKTFPTICPADGRVLTECAEATKDDVDEAVREAWKAFETWKNVPVNQRAAILNKIAD IIDANKEHLAMVETLDNGKPIRETLTVDIPLGAQHFRYFAGCIMAEEGSASILGENILSLILKEPIGVVGQIVPWNFPFL MAAWKLAPVLASGCCSVFKTSSTTSLSVLELARLIQDVIPAGVFNVITGAGSKSGQYMLEHEGFRKLAFTGSTEVGKNVA LAAAEKLIPATLELGGKSANIYFEDCDWEMAMDGLQLGILFNQGQVCCAGSRVFVQESIYDKFVEEAVKRFNQVKVGLPW DEHTQMGSQISKGHMKDILSYIEIGKSEGAAVLCGGEQILEDGLENGAFLRPTLLGNVTNDMRVAQEEIFGPVACIIKFK TEDEAVAMANDSQYGLGGAVWTRDINRAIRVARAVETGRMWVNTYNSIPEGAPFGGYKTSGIGRETHKVILEHYTQTKNI MINLTESPSGFYPVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 3e-106 | 50 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 9e-111 | 50 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 9e-111 | 50 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 9e-111 | 50 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 3e-110 | 50 |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 9e-81 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Closa_1722 | YP_003821941.1 | aldehyde dehydrogenase | VFG0082 | Protein | 1e-106 | 50 |
