Gene Information

Name : Closa_1334 (Closa_1334)
Accession : YP_003821560.1
Strain : Clostridium saccharolyticum WM1
Genome accession: NC_014376
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1438105 - 1440555 bp
Length : 2451 bp
Strand : +
Note : KEGG: eel:EUBELI_00691 ATP-dependent Clp protease ATP-binding subunit ClpC; PFAM: ATPase AAA-2 domain protein; Clp domain protein; ATPase AAA; Clp ATPase-like; SMART: AAA ATPase

DNA sequence :
ATGATAGACAGATTTACGACAAAGGCCAGGACGGCCATTAATCTGGCCGTACAGGCGGCGGAGCGTCTCGGCCACGGATA
CGTGGGAACAGAACACCTGTTAATCGGGCTTTTAGAAGAGGGCGGCGGAGTTGCCGCCAGGGTTCTGGAAGAGAATGGAG
TAAAGGAAGATAAAGTTTTAAACCTTATTAGCCAATTAATTGCCCCGGACCAGGCGCTTCGTTTAAAAGAGGATGGAGGA
TACACTCCCGGTGCAAGAAGGGTTTTGGAAAACAGTTACCGGGAAGCCGTACGGTTTAAGGCAAACTTAATCGGGACAGA
GCATTTGCTTATATCCATTATCCGGGACAACGACTGTGTTGCCTCCAGGCTTTTAAATACCATAGGGATCAGCATCCAGA
AGCTTTATATCGACGTGCTGTCAGCCATGGGCGAAGACGCTCCTGCAAATAAAGAGGAGCTGATGAAATCGCCAAAGGCA
AAAGGAAGCACTCCAACCCTTGACAGCTACAGCAGGGATCTGACGGAGCTTGCGGCACAGGGGAAGCTTGACCCTGTTAT
TGGAAGGGAGTCTGAAATCAAACGCCTGATCCAGATCCTCAGCCGGAGAACCAAGAATAATCCATGCCTGATCGGAGAGC
CTGGAGTGGGAAAGACAGCAGTTGTGGAGGGCCTGGCACAGATGATAGCTGGAGGAGATGTGCCTGAAACCATTGCCGGA
AAAAGACTTCTGACCCTGGATTTATCCGGTATGGTTGCCGGTTCCAAATACAGGGGAGAATTTGAGGAAAGAATTAAAAA
GGTGATCGCCGAAGTGATCGATGATGGGGAAGTGCTTCTTTTCATTGACGAGATTCATACGATTATCGGAGCGGGAGGAG
CGGAAGGAGCCATTGACGCCTCCAACATTTTAAAGCCCTCCCTTGCAAGGGGAGAACTGCAGCTGATCGGTGCAACCACC
ATTGAAGAGTACCGGAAATACATTGAAAAGGATTCTGCTCTGGAAAGGCGTTTCCAGCCGGTTACCGTAGAGGAACCTTC
CGAAGAGGCAGCCATCGGAATATTAAGAGGCCTTAAGGGACGGTATGAGGATCATCATAGGGTTACCATTACGGATGATG
CATTACAAGCGGCGGTGAAGCTGTCTTCCCGGTATATCAATGACCGTTTTCTTCCGGATAAGGCCATTGATGTCATTGAC
GAGGCTTCATCCAAGGTGCGTCTGACCACATATGTAGAGCCGGCTGAGATTAAGGAGCTGGAAGCTGAGATCGAATTGCT
GGAGGATCAAAAGGAAGCTGCCATTAAGGCGGAAGCCTATGAAAAAGCGGGAGCTATTAAGAAAAAGCAGGAAAAGAAAC
GGGAAAAGGTGGAAAAGATCCGGGAGCGGTGGCAGAAGGAAAAAACTTCAAAGAACCTCATTGTAGATGAGGGAGAGATC
GCTGATGTAGTATCAAGCTGGACCAAGATCCCCGTAAGAAAGCTGGAAGAAGGGGAGAGCGAACGTCTCCGCAATCTTGA
GACCATCCTTCATGAGCGGGTGATTGGACAGGAAGAAGCGGTCACCGCTGTGTCAAAGGCCATACGGCGGGGAAGAGTGG
GCCTTAAGGACCCCAAGCGCCCCATTGGTTCCTTCCTGTTCTTAGGCCCTACCGGTGTGGGGAAAACTGAGCTTTCAAAG
GCGCTTTCCGAGGCAATGTTTGGAACGGAACATGCTTTGATCCGTGTAGATATGTCGGAATATATGGAAAAGCACAGCGT
TTCCAAGATGATAGGGTCCCCCCCCGGATATATAGGATATGACGAAGGCGGGCAGCTCAGCGAGAAGGTCCGCAGGAATC
CATATTCCGTAATTTTGTTTGATGAGATTGAAAAAGCCCATCCCGATGTGTTCAATATCCTGCTTCAGGTGCTGGATGAC
GGTCATATCACCGATGCCCAGGGACGGAAAATTGATTTTAAAAACACCGTCATTATCATGACCTCCAATGCCGGAGCGGA
AAACATCATATCTCCCAAGCGTCTGGGTTTTGGCGCAGTTGCGGATGAAAAGGCTGATTATAAGATTATGAAGGACCGGG
TAATGGAGGAAGTAAAACGCCTGTTCAAGCCGGAATTCATTAACAGAATTGATGAGATCATCGTATTCCATCCGTTGAAT
AAGACCCACATGAAGGATATTGTGACGATTATGATGAAGGATATCATGAAACGGACCCGGGAACAGATGAGCATCACCCT
GGAAATTGGAGAGGATGCCAAGGAATACCTGATTAACAAGGGCTACGATGAGAAATACGGCGCAAGGCCCTTAAGGCGTA
CCATTCAGAACTGCCTGGAGGATAAACTGGCGGAAGAGATCTTAAATGGAACGGTAAAAACAGGAGATGAAGTTGCTGTG
ACCGCAGGTGCGGAGGGATTAAAATTTTCTGTCAGGGAGCTGGTAAAATAG

Protein sequence :
MIDRFTTKARTAINLAVQAAERLGHGYVGTEHLLIGLLEEGGGVAARVLEENGVKEDKVLNLISQLIAPDQALRLKEDGG
YTPGARRVLENSYREAVRFKANLIGTEHLLISIIRDNDCVASRLLNTIGISIQKLYIDVLSAMGEDAPANKEELMKSPKA
KGSTPTLDSYSRDLTELAAQGKLDPVIGRESEIKRLIQILSRRTKNNPCLIGEPGVGKTAVVEGLAQMIAGGDVPETIAG
KRLLTLDLSGMVAGSKYRGEFEERIKKVIAEVIDDGEVLLFIDEIHTIIGAGGAEGAIDASNILKPSLARGELQLIGATT
IEEYRKYIEKDSALERRFQPVTVEEPSEEAAIGILRGLKGRYEDHHRVTITDDALQAAVKLSSRYINDRFLPDKAIDVID
EASSKVRLTTYVEPAEIKELEAEIELLEDQKEAAIKAEAYEKAGAIKKKQEKKREKVEKIRERWQKEKTSKNLIVDEGEI
ADVVSSWTKIPVRKLEEGESERLRNLETILHERVIGQEEAVTAVSKAIRRGRVGLKDPKRPIGSFLFLGPTGVGKTELSK
ALSEAMFGTEHALIRVDMSEYMEKHSVSKMIGSPPGYIGYDEGGQLSEKVRRNPYSVILFDEIEKAHPDVFNILLQVLDD
GHITDAQGRKIDFKNTVIIMTSNAGAENIISPKRLGFGAVADEKADYKIMKDRVMEEVKRLFKPEFINRIDEIIVFHPLN
KTHMKDIVTIMMKDIMKRTREQMSITLEIGEDAKEYLINKGYDEKYGARPLRRTIQNCLEDKLAEEILNGTVKTGDEVAV
TAGAEGLKFSVRELVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-180 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Closa_1334 YP_003821560.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 0.0 56