Gene Information

Name : HMPREF0659_A6123 (HMPREF0659_A6123)
Accession : YP_003814189.1
Strain :
Genome accession: NC_014370
Putative virulence/resistance : Unknown
Product : putative type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 1418710 - 1420215 bp
Length : 1506 bp
Strand : -
Note : identified by match to protein family HMM PF02384

DNA sequence :
ATGGCAAAACAAAATACAGCTGATATTGGATTTGAAAAGGAAATATGGAAAGCAGCAGATTTGCTTCGTGGCAATCTTGA
TGCTTCCGAATACAAATCGGTAGTATTGGGATTGATTTTTCTAAAATACATCTCCGATAAGTTTGAGACCAAATATCAAG
AATTAGTCAATAATGGTGAAGGATTCGAGGAAGACCGCGATGAATATATGGCGGATAATATTTTCTTTGTCCCACAAGAA
GCACGGTGGAGTGTGGTAGCAAAAGCAGCCCATACACCAGAAATCGGTACGATAATCGACAATGCCATGCGTCTTATTGA
AAAGGAGAATCTCCGTTTGAAAGGCATTCTGCCCAAAAATTTCGCCCGACCAGAATTAGACAAAAGGCGTTTGGGCGATG
TGGTAGATTTATTTACCAATATTCAAATGAAAGAACATGGAGATTCCAAAGATATATTGGGACGTACATATGAATATTGT
CTTTCTAAATTTGCAGAAGCAGAAGGGAAATTAGCAGGAGAATTTTATACACCTGCTTGTATTGTTCAAACACTTGTCGA
AGTTCTGAAACCTTATCACGGACGAGTATATGACCCTGCTTGCGGATCTGGTGGAATGTTCGTACAGTCTGCCAAATTCA
TAGAAAGGCATCAAGGCAATATCAAAGATATTTCTGTCTATGGTCAAGACAGCAATCCTACGACATGGAAGATGGCTCAG
ATGAATCTTGCCATTCGAGGTATTGAGGCTGATCTGGGTAAGTTTAATGCAGATACATTCTTTGATGATCAACACCCCAC
ATTAAAAGCAGATTTCATCATGGCTAATCCGCCTTTCAATCTCAGTGATTGGGGAGCAGACAAGTTGCAAGATGATGTGC
GTTGGAAATTTGGCATTCCACCATCTGGCAATGCCAACTTTGCATGGTTGCAACACATGATTCATCATTTATCTCCCAAA
GGGAAAATAGGTATGGTATTGGCAAATGGTTCTTTATCTTCACAGACAGGAGGGGAAGGAACGATTCGTGAAAATATCAT
TAAAGCCGATTTAATAGAAGGTATCGTTGCCCTACCCTCACAGTTGTTTTATACCACAGGTATTCCTGTTTCTCTATGGT
TCCTCAATCGAGAGAAGAAACAGAAAGATAAAATTCTGTTTGTAGATGCAAGAAACATGGGAACAATGGTTACTCGCAAA
CTTCGTGAGCTCCAAGAAGCAGATATTAGAAAGATTGCGGACACTTTTGATAAATATAGTGATGGTACACTTGAGAATGA
AAAAGGCTTCTGTGCAGTTGTAGCCCTTGGTGATGTGGCAAAACAAGACTATATTCTTACCCCTGGACGTTATGTCGGCA
TTGCAGAACAGGAAGACGACGGTATTCCTTTCCAAGAGAAGATGGACAAACTCACAACCGAATTGTCCGATTTATTTGCC
CAATCTCATGATTTGGAGGATGAGATACGAAAACAGTTGGCAAGCATAGGTTTCACTATCAAGTAA

Protein sequence :
MAKQNTADIGFEKEIWKAADLLRGNLDASEYKSVVLGLIFLKYISDKFETKYQELVNNGEGFEEDRDEYMADNIFFVPQE
ARWSVVAKAAHTPEIGTIIDNAMRLIEKENLRLKGILPKNFARPELDKRRLGDVVDLFTNIQMKEHGDSKDILGRTYEYC
LSKFAEAEGKLAGEFYTPACIVQTLVEVLKPYHGRVYDPACGSGGMFVQSAKFIERHQGNIKDISVYGQDSNPTTWKMAQ
MNLAIRGIEADLGKFNADTFFDDQHPTLKADFIMANPPFNLSDWGADKLQDDVRWKFGIPPSGNANFAWLQHMIHHLSPK
GKIGMVLANGSLSSQTGGEGTIRENIIKADLIEGIVALPSQLFYTTGIPVSLWFLNREKKQKDKILFVDARNMGTMVTRK
LRELQEADIRKIADTFDKYSDGTLENEKGFCAVVALGDVAKQDYILTPGRYVGIAEQEDDGIPFQEKMDKLTTELSDLFA
QSHDLEDEIRKQLASIGFTIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 8e-148 58
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-146 58
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 4e-148 58
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 9e-115 47