Gene Information

Name : hscN (HDN1F_20350)
Accession : YP_003811263.1
Strain : gamma proteobacterium HdN1
Genome accession: NC_014366
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2527636 - 2528940 bp
Length : 1305 bp
Strand : +
Note : silverDB:HdN1F2680

DNA sequence :
ATGTCTGAATTATTGCTGGACGTTCTGAACAGGATTGAGCCGCGTGTCTATACTGGCCGGGTGGTTGAAGCGTGGGGAAC
CTTGATCCATGTGACAGGAGTGCCGGCCAAGATCGGAGATATTTGTAGGTTGCGGGATCCAGCGAATGGAAATGAGTTGC
TCGCGGAGGCGGTAGGCATCAAGCATCATATTACGCTTTTGAACCCCCTCGGCACGATGGAAGGTGTTTCAAACACGATG
CTGGTTGAAGTAATCGAGGGCGCCTCGACTGTGCCTGTTGGTCGGGAGCTATTGGGGCGAGTTCTGGATTCTCAAGGCTT
ACCCTTGGATGGCAAACCGCCACCGAATTGTGCGCACAGAGCAGCGATCTACGCTGCTGCGCCCGATCCAATGAAGCGAC
TTCCGGTCGATAAGGCATTTTCCACGGGCGTACAGGCAATCGATTCGATGCTAACGCTTGGGCTTGGGCAGCGGGCAGGT
ATTTTCGCGATGGCAGGTGGTGGCAAAAGTACTTTGTTGGGAATGCTTGCGCGGGGCTCTGAGTCTGATGTGAATGTCGT
GGTATTGATCGGGGAGCGCGGCCGTGAGGTGCGGGAATTTATTGATGAGAGTCTTGGGGCAGAAGGGCTCGCGAAAAGCG
TTGTGCTGGTGTCTACGTCGGATCGACCAGCGCTGGAGCGTTGCCGCGTAGCGTTGGTGGGAACTGCGATCGCCGAGTAT
TTTCGTGATAAGGGGTTGCGTGTTTTATTGATGATGGACTCAGTGACACGCTATGCGCGAGCATTAAGGGATATAGGTTT
AGCGTTGGGTGAACCCCCTGTTCGAAGGGGATTTACTCCATCGGTATTTTCGCAGCTTCCAAGGCTATTTGAGCGGGCCG
GCAATAACGAAAAAGGTTATATCACTGGAATTTATACAGTTCTCGCGGAAGATGAGCATGACGGGGAGGATCCAGTAACG
GAAGAAGTAAGGTCGTTGTTGGATGGCCATATCGTGCTGTCTCGAAAACTTGCTGCCGCGGCGCACTACCCTGCAATTGA
CGTATTGGCTAGTGCGAGCCGTGTGATGCATAACGTCACAACTCCGGAACACAGGCAAAAAGCTGCGCGAGTGCGGGCCC
TGATGTCGAAGTATAAGGAGGTTGAGCTTTTGTTGCAGGTTGGAGAATACAAGAAGGGTACGGATGGTCAAGCAGATGAT
GCAATCAGAGCGGCTCCGATGATTGGTGGCTTGCTAAAGCAGGACTCAACTGTTGTCACGCCGTATGCTAGAACGCTGGA
ATTGCTTGAGCGTGCGGTGTCGTGA

Protein sequence :
MSELLLDVLNRIEPRVYTGRVVEAWGTLIHVTGVPAKIGDICRLRDPANGNELLAEAVGIKHHITLLNPLGTMEGVSNTM
LVEVIEGASTVPVGRELLGRVLDSQGLPLDGKPPPNCAHRAAIYAAAPDPMKRLPVDKAFSTGVQAIDSMLTLGLGQRAG
IFAMAGGGKSTLLGMLARGSESDVNVVVLIGERGREVREFIDESLGAEGLAKSVVLVSTSDRPALERCRVALVGTAIAEY
FRDKGLRVLLMMDSVTRYARALRDIGLALGEPPVRRGFTPSVFSQLPRLFERAGNNEKGYITGIYTVLAEDEHDGEDPVT
EEVRSLLDGHIVLSRKLAAAAHYPAIDVLASASRVMHNVTTPEHRQKAARVRALMSKYKEVELLLQVGEYKKGTDGQADD
AIRAAPMIGGLLKQDSTVVTPYARTLELLERAVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-106 57
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-107 57
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-106 56
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-106 56
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-106 56
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-106 56
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-106 56
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-105 56
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-103 55
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-103 55
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-82 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-82 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-82 51
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-83 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 9e-83 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-85 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-85 50
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-75 50
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 9e-76 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 8e-90 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-73 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-74 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-75 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-86 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-87 48
escN AAL57542.1 EscN Virulence LEE Protein 2e-85 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-87 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-87 48
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-85 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-86 48
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-86 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 9e-86 48
escN AAC38383.1 EscN Virulence LEE Protein 7e-87 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-86 48
escN AAC31513.1 L0034 Virulence LEE Protein 4e-87 48
escN AAK26715.1 EscN Virulence LEE Protein 2e-85 48
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-71 48
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-71 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 5e-79 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-71 47
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-72 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-72 47
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-77 46
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-71 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 8e-71 45
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-71 45
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-71 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 5e-75 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-72 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hscN YP_003811263.1 type III secretion system ATPase VFG0390 Protein 6e-105 56
hscN YP_003811263.1 type III secretion system ATPase VFG0192 Protein 6e-108 56
hscN YP_003811263.1 type III secretion system ATPase VFG0048 Protein 1e-101 55
hscN YP_003811263.1 type III secretion system ATPase VFG0515 Protein 5e-83 51
hscN YP_003811263.1 type III secretion system ATPase VFG2144 Protein 3e-90 49
hscN YP_003811263.1 type III secretion system ATPase VFG0812 Protein 2e-87 48
hscN YP_003811263.1 type III secretion system ATPase VFG0730 Protein 4e-87 48
hscN YP_003811263.1 type III secretion system ATPase VFG1254 Protein 7e-77 46
hscN YP_003811263.1 type III secretion system ATPase VFG0555 Protein 3e-71 45
hscN YP_003811263.1 type III secretion system ATPase VFG1778 Protein 6e-71 44
hscN YP_003811263.1 type III secretion system ATPase VFG2459 Protein 2e-75 43
hscN YP_003811263.1 type III secretion system ATPase VFG2331 Protein 1e-71 43
hscN YP_003811263.1 type III secretion system ATPase VFG2499 Protein 9e-73 43
hscN YP_003811263.1 type III secretion system ATPase VFG1008 Protein 3e-68 41