Gene Information

Name : Spirs_2414 (Spirs_2414)
Accession : YP_003804122.1
Strain : Spirochaeta smaragdinae DSM 11293
Genome accession: NC_014364
Putative virulence/resistance : Unknown
Product : GMP synthase, large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2591632 - 2593179 bp
Length : 1548 bp
Strand : -
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991:IPR001962:IPR001674:IPR017926:IPR 004739; KEGG: aae:aq_236 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; asparagine synthase; SPTR: GMP synthase;

DNA sequence :
GTGGACAAGATCCTGATTGTAGATTTCGGCGGGCAAACGGCCCAGCTTATTGCACGGCGGATCAGGGATTTTGGTGTATA
CAGTGATATTGTCGCTCCCGAGACCAATCTTTCGCCGAACATCCTCTCCGATGTGAAGGGCCTGATTTTTTCAGGCTCTC
CCTGGTCGGTCTATGAAGAGGGTGCTCCTGTTGTCCATCCCAGTGCCTATGAAAGCGGTTTGCCTATTCTCGGTATCTGT
TACGGTTTTCATCGGATGACCACCGATTTCGGGGGATCGGTCCTTGGACTGGCAAAGAAAGAGTATGGTAGAGCCGCCTT
GCGCTTTCCCAAGCCCTCTAAACTCTTCGATGGGGTTCCCGAGGGCTTTATTAGCTGGATGAGCCATGGAGACAGCATCG
CCGAAGTTGCAGAGGGTTTTCAGATTACCGCACGAAGTGCAGACCATCCAGCTGCGGCAGAAGATCCCGAAAAGAGGCGT
TACGGCCTTCAGTTCCATCCCGAAGTGACCCATTGTGAGTATGGGATTAAGATCCTTGAGAATTTTGTCTTTGGTATTTG
TGGTGCCGATAAGGGCTGGAGTATGGAGGGCTACCTCGAGGAGGTTTCTGCCTCCATCAAAAAACGGGTTGGCGACCATC
CTGTTCTTCTTCTTATCTCGGGAGGGGTCGACTCTTCGGTGGTTGCCGGTGTCCTGCTTTCGGCGCTTGATCCGGAAAAG
GTGCACCTGATGTATATCGATACGGGGCTCATGCGCAAAGGTGAGACCGAAGCGGTGCGTAAAAGCCTTGAGGCCCTTGG
TGCTACCCATCTTTCGATCATCGATGCGGGTGACCGATTTTTACATGCTTTGGAAGGGGTCGATGATCCCGAAGAGAAAC
GGCGGATCATTGGAGACCTCTTTGTCGAGGTGCAGAAGAGTGACATCGTCGGGAAGATCGACGGGGATTATTTCCTTGCC
CAGGGCACCCTATATACCGACCTGATAGAGTCGGGTAAGGGGGTCGGCAAGAACGCCAAGGTAATCAAAAGCCATCACAA
TGTGCGCAGCCCCCTCATCGAGGCAAAGCGAAACGCCGGTATGATCATCGAACCCCTGGACCGACTCTACAAGGACGAGG
TCAGACGACTTGGGCGGCTTATCGGCCTATCCGAGAGTGTGGTGGGACGCCACCCCTTTCCCGGGCCAGGCCTTGCAGTG
AGAATCCTCGGGGCGGTTGACCGGGAAAAGTGCAGGATCCTGCGGGAGGCGGATGCCATATTCATCGAGGAACTCCATCG
CCGGAAGCTCTACGACGAGATATGGCAGGCCTTTGCCGTTCTTCTTCCGATCAAGTCGGTAGGGGTAACAGGGGATGCAA
GGCGTTACGGCTATGTTCTTGCCCTTCGGGCGATTGTCAGCCATGACGGAATGACCGCCGACGTATATCCCTTTGATACA
AAGGACCTGCTTGAAATTTCTTCGCTTATCACAAACTCCGTATCGGAAATCGGCCGGGTTGTCTACGATGTATCGAGTAA
ACCCCCCGCTACCATTGAGTGGGAGTAG

Protein sequence :
MDKILIVDFGGQTAQLIARRIRDFGVYSDIVAPETNLSPNILSDVKGLIFSGSPWSVYEEGAPVVHPSAYESGLPILGIC
YGFHRMTTDFGGSVLGLAKKEYGRAALRFPKPSKLFDGVPEGFISWMSHGDSIAEVAEGFQITARSADHPAAAEDPEKRR
YGLQFHPEVTHCEYGIKILENFVFGICGADKGWSMEGYLEEVSASIKKRVGDHPVLLLISGGVDSSVVAGVLLSALDPEK
VHLMYIDTGLMRKGETEAVRKSLEALGATHLSIIDAGDRFLHALEGVDDPEEKRRIIGDLFVEVQKSDIVGKIDGDYFLA
QGTLYTDLIESGKGVGKNAKVIKSHHNVRSPLIEAKRNAGMIIEPLDRLYKDEVRRLGRLIGLSESVVGRHPFPGPGLAV
RILGAVDREKCRILREADAIFIEELHRRKLYDEIWQAFAVLLPIKSVGVTGDARRYGYVLALRAIVSHDGMTADVYPFDT
KDLLEISSLITNSVSEIGRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-95 47
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-95 47
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-95 47
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-86 42