Gene Information

Name : Spirs_2202 (Spirs_2202)
Accession : YP_003803912.1
Strain : Spirochaeta smaragdinae DSM 11293
Genome accession: NC_014364
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : -
Position : 2356339 - 2357256 bp
Length : 918 bp
Strand : +
Note : COGs: COG2367 beta-lactamase class A; InterPro IPR000871:IPR001466; KEGG: aby:ABAYE3623 beta-lactamase VEB-1; PFAM: beta-lactamase; SPTR: beta-lactamase; PFAM: beta-lactamase

DNA sequence : 
ATGAAGAGAATGTTCTCCTTAAGTTATATGTTGCTTGTTTTCGTTTCTTTTTCTTTTGGTGAAACCAATGCACCCAAAAC
AATAAATAATCTCAGGCAGGATATTGAGCAATTTCTCGTTGAAAAGAAAGCACTTGTGGGAGTTTCTGTTCTTGGCATTG
AAGATAATGAATCATTAAGCATCAACAATGATAAACACTTTTCTATGCAAAGTGTTTATAAATTCCACATTGCATTATCA
GCTTTACATGAAGTTGATACTGGTAACCTTTCTTTGGAAGACAGTATAATGCTAAAAGAGAGTGATTTATTACCGAATAC
GTGGAGCCCTTTGCGTGAAACATACCTTGCAGGAAAAAAAGAAATTACCTTAGCTGAATTAATTAATTACACTGTTGCAT
TAAGCGACAATAATGGTTCTGATATTTTATTACGCTTAATAGGTGGTACTGAAAAAGTAAACGAGTATATTCATGGTCTT
GGCATCATTGATGTTCAGATTACAACCGATGAAGAGAATATGCACAAAGAATCTGATCTTCAATTTGAGAATTGGACAAC
GCCAGAAGCCGCCACAGAATTACTTACATTATTTTATGATGGAAAGGTCTTGTCAAAACAATCAACTGATTTTTTATGGA
AAGTTATGGCAGGAACGGAAACAGGTGGAGGTAGGATTAAGGGCAAATTGCCATCTGGAACTTTAGTAGCGCATAAGACT
GGAACTTCTGCACCGCCAGATGAATCCGGGGTAACTGTAGCAATTAATGATATAGGAATTGTAACATTGCCTAACAATAA
CCATTTTGTGATGAGTGTCTTTGTAGCTAACTCGAAAGAGAGTTATGAAACGAATGAAAAGATTATAGCTGATATCACAA
AGCTTGTATGGAATTATTTTACCCACAAAGCAAATTGA

Protein sequence : 
MKRMFSLSYMLLVFVSFSFGETNAPKTINNLRQDIEQFLVEKKALVGVSVLGIEDNESLSINNDKHFSMQSVYKFHIALS
ALHEVDTGNLSLEDSIMLKESDLLPNTWSPLRETYLAGKKEITLAELINYTVALSDNNGSDILLRLIGGTEKVNEYIHGL
GIIDVQITTDEENMHKESDLQFENWTTPEAATELLTLFYDGKVLSKQSTDFLWKVMAGTETGGGRIKGKLPSGTLVAHKT
GTSAPPDESGVTVAINDIGIVTLPNNNHFVMSVFVANSKESYETNEKIIADITKLVWNYFTHKAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
bla VEB-1 CAJ77043.1 Betalactamase Not tested AbaR1 Protein 2e-60 48
ABK1_0262 YP_005512834.1 Extended-spectrum beta-lactamase PER-1 precursor Not tested AbaR4d Protein 1e-48 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spirs_2202 YP_003803912.1 beta-lactamase EF420108.1.gene1.p01 Protein 4e-60 48
Spirs_2202 YP_003803912.1 beta-lactamase AF010416.1.gene1.p01 Protein 1e-60 48
Spirs_2202 YP_003803912.1 beta-lactamase EF136375.1.gene1.p01 Protein 5e-60 48
Spirs_2202 YP_003803912.1 beta-lactamase AY027870.1.gene1.p01 Protein 2e-60 48
Spirs_2202 YP_003803912.1 beta-lactamase NC_010410.6002875.p0 Protein 1e-60 48
Spirs_2202 YP_003803912.1 beta-lactamase AY536519.1.gene1.p01 Protein 5e-60 48
Spirs_2202 YP_003803912.1 beta-lactamase GQ396303.1.gene1.p01 Protein 5e-46 43
Spirs_2202 YP_003803912.1 beta-lactamase AY740681.1.gene9.p01 Protein 1e-50 42
Spirs_2202 YP_003803912.1 beta-lactamase FJ627180.1.gene1.p01 Protein 3e-49 42
Spirs_2202 YP_003803912.1 beta-lactamase X93314.gene.p01 Protein 1e-45 42