Gene Information

Name : Spirs_1928 (Spirs_1928)
Accession : YP_003803648.1
Strain : Spirochaeta smaragdinae DSM 11293
Genome accession: NC_014364
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2084082 - 2086619 bp
Length : 2538 bp
Strand : +
Note : COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR001270:IPR003593:IPR018368:IPR001943:IPR 004176:IPR003959:IPR013093:IPR019489; KEGG: gwc:GWCH70_0083 ATPase AAA-2 domain protein; PFAM: ATPase AAA; Clp domain protein; AAA ATPase

DNA sequence :
ATGTTTAAGGGCTTGACCCAGAGAGCACAGCGCATATTGACTATCTACGCTCAGGAAGAAGCAAAACGATTTCATTCCGA
CCAACTGCTCCCTGAGCATATTATTCTGGCTCTGTTGAAAGACGGGGAAGGACTGGGATATCGTGCCTTGCAGGTGATCA
AAGTCGATCCCGAAGAGCTCCAGATAGAGCTTGAGAAGAGTATTCCCCGCAAACATGCAGGTTTTATTCTCGGAGATGTG
CCTCCCAGTCATCGAGGGAAAAAGCTCCTTGAAGATTCGGCTGAGGAGGCCCGCGCCCTCGGACATGAATATATCGGAAC
CGAACATCTTTTGCTTTCTGCATCCAAAGAGGCAGGAAGTGTCGTCCAGCGTTTTCTTGCAAAGCGGAATATCGGTGTGG
AAATAATTCGCCAAACCATCGCTGAGCTGCGGGGAAGCGGGCGGACAGAGCGCTCTGCCGGCAACACCGTTATCGGAGCA
TCCGGTTCCGAACATGCAGAACCCCCGAACTTGGGGTTCAGAAAACGGGGGGGAGCGGCCCAATCGAAAAAATCGACGCC
GACATTGGATGAGTTTTCTCGTGATATGACGAAGTTCGCACATGATGGGAAACTCGATCCCGTAATCGGTAGGGATTTTG
AAATACAGCGTGTCATTCAAATTCTTGCTCGCCGTACAAAGAATAATCCTGTCCTTATCGGTGAACCCGGGGTTGGCAAA
ACCGCTATCGTCGAAGGCCTTGCCCAAATGATTGAGGACGGCTCCGCTCCTGAAGTCCTTTCGGGAAAGCGGGTGTTAAC
GCTTGATCTCGCTTCTCTTATCGCCGGCACCAAGTATCGCGGTGAGTTTGAGGAACGACTTAAAAGGGTTATGAAGGAGA
TACAGAACGCAGGGAATGTCATTCTTTTCATTGATGAACTCCATACGATCATCGGTGCCGGTGGTGCCGAAGGTGCTATT
GATGCTTCCAACATGTTGAAGCCGGCCCTTAGCCGTGGAGAACTTCAGTGCATTGGAGCAACGACCCTCAACGAATATCG
AAAGCATATTGAAAAGGATGCGGCTCTGGAACGTCGTTTCCAGACCATATTTGTTGAAGAGCCTTCCGTTGAAGAAACAG
TTGGAATCTTGGAGGGAATTCGGGAACGATATGAGGAGCATCACAATGTTTCGTATAGTGACGAGGCCCTGGAAGCCGCT
GCTCATCTCTCACATCGTTATATCAGCGACCGGTTTCTTCCCGATAAGGCAATCGATCTCATTGACGAGGCGGGATCTTT
TAAGCGGATTCATAATACGGTACGGCCGAAGGCACTCATTCAGCTTGAAGAAGACATTGAACGTCTTACCGGAGAAAAGA
TTGCATTGGTCAATAATCAGGATTATGAAAAGGCTGCTGCGGTCCGTGATGATGTACGTCGTCTCAAAGGTAAGGTTGAA
GAACTTCAGAGTCAGTGGAAAAGCAATATGCGCAGCGAAAGAAGTACTGTCGGTCCTGAAGATATCCAGGCCATCGTTTC
CAGAATTACGGGTATCCCCCTTGCGCGGATCGTACAGAGCGAATCGGAGAAGCTGCTGAAAATTGAGGAAGAACTGCACA
AAACGGTTATCGGACAGGATGAGGCTATCTTGGCTATCGCGAGTAGTATTCGCAGGTCGAGGACCGGCCTCAGTAGTCCG
AAACGTCCTCTCGGTTCCTTTATCTTCCTCGGGCCAACAGGTGTCGGAAAAACCCTATTGGCTAAGACGCTTGCACAGTT
TCTCTTTGGTGATGAAGAGGCCCTCGTTCGGGTGGATATGTCCGATTACATGGAAAAGCATAATGTGAGCAGACTCGTCG
GAGCGCCTCCCGGCTATGTCGGTTATGAAGAGGGAGGCGTCCTTACCGAGAAAATTCGCCGACGCCCTTACAGTGTCATC
CTTCTCGACGAGATTGAGAAAGCACATCCGGATGTATTTAATCTTTTGCTGCAGGTACTTGAGGAAGGTGAACTTCATGA
TAATCTCGGTCACAAGGTCAGCTTTCGCAATAGCGTGCTTATCATGACCAGTAATGCCGGTGCCCGTGAAATCAGTAAAA
GTGGGGCTCTTGGATTTCAGGCCTCCGAGGGTGTCATGAGTCATGCGGAAATCAAGGCCTCCGCTATGAATGAATTACAG
CGTAGTTTCCGTCCCGAATTTATTAATCGTGTCGATGAGATTGTTGTCTTCACGAGCTTGAAGCGGCCGGAGATTCGAAA
AATCCTCGATATTCTTCTTTCCGAAATCTCACTTCGTTTGCTGGAAATGAATATCATCCTTGAGGTAAAGCAAAGTGCAA
AAGACTATTTCATCGATAAGGGCTATGATGTCAAATATGGTGCGAGGCCGTTGCGTCGTGTCTTGCAAAAGGAACTTGAA
GATCCGCTTTCCATGGAAATGCTGAAAGGCCGTTGCGTCTCCGGAACCCATATGATAGTCGGTATCAGAAAAGGGGAAAT
CCATTTTACGGCCCGGCAGCCCCAGGTAGTAAAAGATCATGCAGGGATCACTCAATAG

Protein sequence :
MFKGLTQRAQRILTIYAQEEAKRFHSDQLLPEHIILALLKDGEGLGYRALQVIKVDPEELQIELEKSIPRKHAGFILGDV
PPSHRGKKLLEDSAEEARALGHEYIGTEHLLLSASKEAGSVVQRFLAKRNIGVEIIRQTIAELRGSGRTERSAGNTVIGA
SGSEHAEPPNLGFRKRGGAAQSKKSTPTLDEFSRDMTKFAHDGKLDPVIGRDFEIQRVIQILARRTKNNPVLIGEPGVGK
TAIVEGLAQMIEDGSAPEVLSGKRVLTLDLASLIAGTKYRGEFEERLKRVMKEIQNAGNVILFIDELHTIIGAGGAEGAI
DASNMLKPALSRGELQCIGATTLNEYRKHIEKDAALERRFQTIFVEEPSVEETVGILEGIRERYEEHHNVSYSDEALEAA
AHLSHRYISDRFLPDKAIDLIDEAGSFKRIHNTVRPKALIQLEEDIERLTGEKIALVNNQDYEKAAAVRDDVRRLKGKVE
ELQSQWKSNMRSERSTVGPEDIQAIVSRITGIPLARIVQSESEKLLKIEEELHKTVIGQDEAILAIASSIRRSRTGLSSP
KRPLGSFIFLGPTGVGKTLLAKTLAQFLFGDEEALVRVDMSDYMEKHNVSRLVGAPPGYVGYEEGGVLTEKIRRRPYSVI
LLDEIEKAHPDVFNLLLQVLEEGELHDNLGHKVSFRNSVLIMTSNAGAREISKSGALGFQASEGVMSHAEIKASAMNELQ
RSFRPEFINRVDEIVVFTSLKRPEIRKILDILLSEISLRLLEMNIILEVKQSAKDYFIDKGYDVKYGARPLRRVLQKELE
DPLSMEMLKGRCVSGTHMIVGIRKGEIHFTARQPQVVKDHAGITQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-177 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spirs_1928 YP_003803648.1 ATPase AAA VFG0079 Protein 0.0 53
Spirs_1928 YP_003803648.1 ATPase AAA VFG0080 Protein 3e-142 53