Gene Information

Name : Spirs_1565 (Spirs_1565)
Accession : YP_003803286.1
Strain : Spirochaeta smaragdinae DSM 11293
Genome accession: NC_014364
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1680412 - 1681773 bp
Length : 1362 bp
Strand : +
Note : COGs: COG1157 flagellar biosynthesis/type III secretory pathway ATPase; InterProIPR005714:IPR020005:IPR004100:IPR000194:IPR 020003:IPR003593; KEGG: tde:TDE1218 flagellum-specific ATP synthase FliI; PFAM: H+transporting two-sector ATPase alpha/subunit beta

DNA sequence :
ATGACCGCTCTTTTTCAGAAATATACCGATGTTCTGGAACGAATGGATCCGATCAAGGAGATTGGTACCGTCCGTGAGGT
CAAGGGGCTGCTTGTGGAGAGCCACGGACCCCAGGTCGTTGTCGGAGAATTATGTCAGATCCTTACCTCGGGAGGGGAGC
CGGTATGGGCCGAGGTCGTCGGTTTTCGGGACAGAACCGTTCAGCTGATGCCCTTCGAATCAATGGACGGAATCGAGCCT
GGCTCCCAGGTCGTAGCGATGGGTGAAACTCTTTCCGTTCCCGTTTCCGAAAAGATGCTTGGGAGGGTCCTTGATGCCAT
GGGCCGCCCCATTGACGGAAAGGGGCCGGTCGGCGGGGCTGAAAGCGTCTCCACGGTCAACACCCCTCCAAATGTACTGA
CTCGTAAGCCAATCAAGCGTCAGATGGTTACCGGGGTCCGGGCGATCGACACCATGACCCCTATCGGCAAAGGACAGCGC
ATTGGTATCTTTTCGGGAAGCGGAGTGGGAAAATCGACCCTTTTGGGGATGATCGCGCGCAACACCTCGGCCGATATCAA
TGTCATCGCCCTCATCGGGGAACGAGGACGGGAGGTCCAGGAGTTTATCGAGTACGACCTCGGGCCTGAAGGGCTCGAGC
GTTCCATTCTCGTTGTCTCCACCGGTGATACCGCTCCTTTGAGCCGACTTCGCGGAGCCTTTGTGGCTACCACCATCGCC
GAGCATTTTCGTGACAAGGGTGCGGATGTCATGCTCTTGTTCGATTCGGTTACCCGCTTTGCCAGAGCCCAGCGTGAGAT
TGGCCTTGCGGTCGGAGAACCTCCCGCCACCAGGGGCTACACGCCCTCCGTTTTTTCCACCCTTCCGAAGCTGCTTGAGC
GCTGCGGGACAGGAGAGCGGGGAACTATTACCGGTTTTTATACCATCCTTGTGGAGGGCGATGATATGGATGAGCCGGTT
GCCGACGCCGTTCGTGGTATTCTGGATGGACATATCGTCTTGAGCAGGAAGTTGGCCCAGGCCTATCGTTATCCTGCCAT
CGATGTGCTTGCCAGTTTAAGCCGTCTCGGAACGAAGATCACCTCTCCTTTGGTCCAGAAGGCCTCAGGAAAGCTTAGAT
CGCTTCTCGCGGTCTATACCGACGCCGAGGATCTGATCAATGTCGGAGCCTATGCCGAAGGCAGTAATTCCGCCATCGAC
GAGGCGATAGAAAAGATCGATGCGATTCGTGAATTCCTGGGACAAGGCATTACCGAAGCGGCACCGATCAGAGAAACCAT
AGCCCGTATGGGAGCGATTGCGGGAATTCCCATTCCTGAAGAGGAGCTGGACGCATATGAAACGGTTTCAATTCGCGCTT
GA

Protein sequence :
MTALFQKYTDVLERMDPIKEIGTVREVKGLLVESHGPQVVVGELCQILTSGGEPVWAEVVGFRDRTVQLMPFESMDGIEP
GSQVVAMGETLSVPVSEKMLGRVLDAMGRPIDGKGPVGGAESVSTVNTPPNVLTRKPIKRQMVTGVRAIDTMTPIGKGQR
IGIFSGSGVGKSTLLGMIARNTSADINVIALIGERGREVQEFIEYDLGPEGLERSILVVSTGDTAPLSRLRGAFVATTIA
EHFRDKGADVMLLFDSVTRFARAQREIGLAVGEPPATRGYTPSVFSTLPKLLERCGTGERGTITGFYTILVEGDDMDEPV
ADAVRGILDGHIVLSRKLAQAYRYPAIDVLASLSRLGTKITSPLVQKASGKLRSLLAVYTDAEDLINVGAYAEGSNSAID
EAIEKIDAIREFLGQGITEAAPIRETIARMGAIAGIPIPEEELDAYETVSIRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-84 51
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-90 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-95 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-96 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-96 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-96 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-96 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-94 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-94 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-85 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 6e-85 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-85 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-85 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-85 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-95 49
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-95 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-76 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-77 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-77 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-74 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-80 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-77 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-77 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-77 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-76 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-76 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-86 43
escN AAC38383.1 EscN Virulence LEE Protein 2e-75 43
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-74 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-75 43
escN AAC31513.1 L0034 Virulence LEE Protein 2e-75 43
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-73 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-74 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-75 43
escN AAK26715.1 EscN Virulence LEE Protein 2e-74 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-74 43
escN AAL57542.1 EscN Virulence LEE Protein 2e-74 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-75 43
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-74 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-75 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-75 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 9e-76 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG2144 Protein 4e-100 55
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG0192 Protein 2e-95 50
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG0515 Protein 1e-85 50
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG1254 Protein 6e-92 49
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG0048 Protein 5e-93 49
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG0390 Protein 1e-88 49
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG2499 Protein 2e-80 47
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG2331 Protein 3e-79 44
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG0730 Protein 1e-75 43
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG0812 Protein 1e-75 43
Spirs_1565 YP_003803286.1 flagellar protein export ATPase FliI VFG2459 Protein 7e-70 41