Gene Information

Name : Spirs_1422 (Spirs_1422)
Accession : YP_003803143.1
Strain : Spirochaeta smaragdinae DSM 11293
Genome accession: NC_014364
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1519739 - 1520926 bp
Length : 1188 bp
Strand : -
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: tte:TTE1585 cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: cystathionine beta-lyas

DNA sequence : 
ATGAGTTCCAGGCACGGCTTCGAAACCCGACAAATCCACGCAGGAAGCACTGGTCCCAATCCCGAAAAGGCGCTAAATCC
GCCTATTTTCATGACCAGTACCTTCACCTTCGATTCCATCGCCGCGGTGGATGATGTTATGAGCTTTCGCAGCGACGATT
ACGTCTACACCAGGGGAAACAATCCTACGCTCAGACTCTTCGAAAACAGGATGGCCGACCTGGAAAACGGCGTCGGTGCG
GTTGCCTTTGCATCGGGGATGGCGGCAATAAGCTCGACCCTTTTCAGTCTCCTGAAACCGGGGGATTCGGTCGTGGCGCA
TAAAACCCTCTATGGATCAAGCCATTCGGTAATAACGACGCTCCTGCCCCGCTACGGAATTCGTTCCATCATCGCCGACC
TCACGCTCCCTGGCGAGCTGGAACGGAAGGCCGATAAGAACACCAAGCTTGTCTACTTCGAAACACCAGCCAACCCCGAT
CTTTCCATTATCGATATACGGCAAATCGCCGAACAGGCGGCAGCCATTGGTGCAAAGGTCGTAGTGGACAACACCTTTGC
AACCCCCTTTCTGCAAAGGCCCCTTGACCTCGGCGCCTTTGCAGTGGTTCATAGTGCGACAAAGTATCTTTGCGGGCACG
GTGATGTATTGGGTGGAGTGACGGTTTCAAAGGATATGGATTACATCCACGAACTGAAATTCGGTTATATGTGCGAATTT
GGGGGAACCATGAGCCCCTTCAACGCATGGCTCCTGCTTCGCGGAATGAAAACCCTCTCTTTGAGGATGGAACGCCACCA
GGAAAATGCAAAAAAAGTTGCTAAATTCCTTCTTCAGCACCCGAAGGTCTCTAAGGTTCTCTATCCGGGACTGACCGATC
ATCCGGGACACGAGACGGCAAAAAAACAGATGAGCGGCTTTGGAGCCATGATCAGCTTCGAGGTGGCGGGCGATCTCTCT
GCCACAAGTCATGTGGTCGATGCCATGAAACTTCCGGCCCTTGCCGTAAGCCTCGGCGACTGTGAAACCCTCGTAGAACT
TCCCGCTGCCATGACCCACCGCGGTTACGACAGGGAGCATCTTGCCGAGTTCGGGCTTACCGAAAGCATGATACGGCTCT
CCATCGGTCTCGAAAGCGTTGTCGATATCATCGAGGACCTGGGGCAGGCCCTGGGTCGGCTTTCATGA

Protein sequence : 
MSSRHGFETRQIHAGSTGPNPEKALNPPIFMTSTFTFDSIAAVDDVMSFRSDDYVYTRGNNPTLRLFENRMADLENGVGA
VAFASGMAAISSTLFSLLKPGDSVVAHKTLYGSSHSVITTLLPRYGIRSIIADLTLPGELERKADKNTKLVYFETPANPD
LSIIDIRQIAEQAAAIGAKVVVDNTFATPFLQRPLDLGAFAVVHSATKYLCGHGDVLGGVTVSKDMDYIHELKFGYMCEF
GGTMSPFNAWLLLRGMKTLSLRMERHQENAKKVAKFLLQHPKVSKVLYPGLTDHPGHETAKKQMSGFGAMISFEVAGDLS
ATSHVVDAMKLPALAVSLGDCETLVELPAAMTHRGYDREHLAEFGLTESMIRLSIGLESVVDIIEDLGQALGRLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-52 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spirs_1422 YP_003803143.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 3e-72 44