Gene Information

Name : cztR (NIDE0305)
Accession : YP_003796011.1
Strain : Candidatus Nitrospira defluvii
Genome accession: NC_014355
Putative virulence/resistance : Virulence
Product : heavy metal response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 270422 - 271093 bp
Length : 672 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 11004187, 11283292, 11399769, 12829274, 8078459, 8449873; Product type r : regulator

DNA sequence : 
ATGCGTGTCCTCGTCGTTGAAGATGAAACCAAGGTAGGCTCCTTCATCAAGCGAGCGCTTGAGGAGGAGAGTTACGCCGT
CGATCTCTGCGAGGACGGCGCGCAAGGCCTCGACATGGCCTTGAGCGGCAGTTACGACCTCATCATGATCGATCTCATGC
TGCCGAGCCTGCCCGGGCTGGAAGTACTCACACGCCTCCGCAAGGAAAAGATTCAGACCCCCGTGCTGATCCTGACGGCG
CAATCAAAAGTGGACCAGCGGGTCAAGGGACTGGACGCCGGCGCGGACGACTACCTCACGAAGCCCTTCGCCATCGATGA
ATTGCTCGCGCGTGTGCGGGCCCTGTTGCGACGCGGCACGGCCGAATCTTCCGGCACGCTCCAGATCGACGATCTCCTGC
TCAATCCGGCCACACGCGAAGTCACGCGCGGCGGACAACGCATCGACCTGACGGTGAAGGAATATGCGCTGCTCGAATAT
TTCATGCGCCATGCCGGGCGGGTACTGACTCGTCCCATGATTTCCGACCATGTCTGGAATCAGGACTTCGACACCTTCAC
GAATGTGATCGACGTCTATGTGAACTACTTGCGGAATAAGATCGATCGCGGACGCGCGCGAAAGTTGATCCATACGATTC
GAGGGAGTGGGTACATGCTCAAGGTGGACTGA

Protein sequence : 
MRVLVVEDETKVGSFIKRALEEESYAVDLCEDGAQGLDMALSGSYDLIMIDLMLPSLPGLEVLTRLRKEKIQTPVLILTA
QSKVDQRVKGLDAGADDYLTKPFAIDELLARVRALLRRGTAESSGTLQIDDLLLNPATREVTRGGQRIDLTVKEYALLEY
FMRHAGRVLTRPMISDHVWNQDFDTFTNVIDVYVNYLRNKIDRGRARKLIHTIRGSGYMLKVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-37 44
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-36 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cztR YP_003796011.1 heavy metal response regulator BAC0638 Protein 2e-39 52
cztR YP_003796011.1 heavy metal response regulator BAC0083 Protein 3e-46 51
cztR YP_003796011.1 heavy metal response regulator BAC0111 Protein 1e-50 51
cztR YP_003796011.1 heavy metal response regulator BAC0308 Protein 5e-44 50
cztR YP_003796011.1 heavy metal response regulator BAC0197 Protein 6e-44 50
cztR YP_003796011.1 heavy metal response regulator BAC0125 Protein 5e-44 48
cztR YP_003796011.1 heavy metal response regulator BAC0347 Protein 2e-43 47
cztR YP_003796011.1 heavy metal response regulator AE015929.1.gene1106. Protein 2e-31 45
cztR YP_003796011.1 heavy metal response regulator HE999704.1.gene1528. Protein 2e-39 45
cztR YP_003796011.1 heavy metal response regulator NC_013450.8614146.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_002951.3238224.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_007793.3914065.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_002758.1121390.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_010079.5776364.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_002952.2859858.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_007622.3794948.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator NC_003923.1003417.p0 Protein 8e-33 44
cztR YP_003796011.1 heavy metal response regulator BAC0487 Protein 9e-29 42
cztR YP_003796011.1 heavy metal response regulator CP001485.1.gene721.p Protein 2e-29 41
cztR YP_003796011.1 heavy metal response regulator AE016830.1.gene1681. Protein 7e-37 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cztR YP_003796011.1 heavy metal response regulator VFG1390 Protein 7e-44 50
cztR YP_003796011.1 heavy metal response regulator VFG0596 Protein 6e-38 44
cztR YP_003796011.1 heavy metal response regulator VFG0473 Protein 2e-29 43
cztR YP_003796011.1 heavy metal response regulator VFG1386 Protein 4e-39 42