Gene Information

Name : clpB3 (NIDE2457)
Accession : YP_003798092.1
Strain : Candidatus Nitrospira defluvii
Genome accession: NC_014355
Putative virulence/resistance : Virulence
Product : chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2402628 - 2405057 bp
Length : 2430 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10982797, 11580258, 12054807, 12205096, 12475170, 12624113, 14567920, 14640692, 14738756, 15037248, 15554981, 2066329, 2185473; Product type f : factor

DNA sequence :
ATGTTCGAACGGTTCACGGACAAGGGTCGCAAGATCATCATCCTGGCACGTGAAGAAGCCGAGCGCCATCAGAACGATTA
CCTGGGCACCGAGCACCTGGTGTTGGCCATCCTTCGCGAGACGGATGGGATTGCGCTGATGATCCTCAAGAAAATGGGGC
TCTCCACCGAGCAGATTCGACTCGAAATCGAGCGGAATCTCCCGGGTGGGGGCACAACGATGACCTTCGGGGAAATTCCC
TTCAGCCCGCGGGTCAAGAAAGTCATCGAGTACGGGGTGGAAGAAGCCCGGTTGCTCGGTCATAACCACATCGGCAGCGA
ACATCTGCTGCTCGGTCTCCTTCGGGAGGAAGAAGGCATCGGCGGGAAGATTCTCCGGAGTCTGGGCGCCAACCTCCTGA
CCGCGCGGCAACTCACCGTCACCTTCCTGCGTAAGTCTGCGCCGCGTGAGCGGGATCGCAAGAGCAATACGCCGGCTCTC
GATGAATTCGGACGCGACCTGACCCAGCTGGCCCAGGAGGGGCAGTTGGATCCTGTCATCGGTCGCGCGGACGAAATCGA
GCGGGTCTTGCAGATTCTCAGCCGACGGTCGAAAAACAATCCGGTCCTCATCGGCGAATCCGGCGTGGGAAAGACAGCCA
TCGTCGAAGGACTCGCGCAGCGTATCATCGCGTCGGAAGTCCCCGACAATCTGCTGTCTCGTCGCGTCATCGCACTCGAC
CTGGGCTCGCTGGTGGCAGGCACGAAATACCGCGGCCAGTTTGAAGAACGCCTCAAGGTCGTGATGAAGGAGATCGTGCA
GGCCGGGAACATCATTATCTTCATCGACGAATTGCACACGTTGGTCGGGGCAGGGGCGGCAGAAGGATCGATCGATGCCT
CCAACATGCTCAAGCCGGCGTTGTCCCGCGGTGAAATTCAGTGCATCGGCGCCACGACGCTCGACGAATACCGCAAACAC
ATCGAGAAAGACGGCGCGCTCAAACGTCGCTTCCAACCCATTCACGTGCAGCCGCCCAGCACGGATGAAACGGTACGGAT
CATCCAGGGCTTGCGGGACCGGTACGAGGAACACCATGGGGTGGAAATCACGGAAGATGCCATCGTGGAAGCCGTCAAGT
TGGCGGATCGTTATATTACCGACCGGTTCCTTCCGGACAAGGCTATCGACCTGATCGACGAAACCGGCTCGCGAGCGAAG
TTGCAGACCTACGCGCTGCCGACTGAGCTCAAAGCGCTGGAGCAAGAGCTCAAGAAAATTTCCCGCGATAAAGAGCTGGC
GATCTCGATGCAAAACTTCGAGGAAGCCGTCCGTCATCGCGAAGAAGAAGAGCGTCTGCGAAAGCTCCTCGACGAATCCA
AGCGGGAGTGGAAGAAGAATCAGGAGAAACACAAGCCGACCATCGGCAAGGAAGAAGTCGCGTATGTCGTCTCGAAGATG
ACCGGCATTCCGCTCTTCAAGTTGGAAGAAGAAGAGTCCAATAAACTGCTCCGCATGGAAGAATTCCTCCACAAGCGGGT
CATCGGACAGAACGAAGCTATTTCGGCTGTGGCGCGTGCCATTCGTCGATCCAGAGCGGGCCTCAAGGAAGCGAAGAAAC
CCATCGGCTCCTTCATTTTCCTCGGCCCGACCGGTGTCGGAAAAACGGAATTGGCACGGACCCTCGCGGAGTTTCTCTTC
AACAGCGAAGATGCGCTCATCCGGATCGATATGTCCGAGTATCAGGAAAAGTTCACAAGCTCACGCCTCTTCGGAGCCCC
TCCGGGATACGTCGGCTACGAGGAAGGCGGCCAGCTCACTGAAAAGGTTCGACGTCGTCCTTACTCGGTCGTGCTGTTCG
ACGAAATCGAGAAAGCGCATCCGGACGTGTTCAACGTCCTGCTGCAGGTGCTCGACGACGGTGTCCTCACGGACAGCCTG
GGTCGAAAGGTCGATTTCAAGAACACGGTCGTGATCATGACCTCGAACATCGGCACGAAAATGATCCAAAAAGGCGTCTC
GCTCGGATTCCAGAATGATGAAAAGGGCGGACAGGCCTTGCGCCGCAAAGAAGACGTGATGGGAGAACTCAAGCGTTCGT
TCAGCCCGGAGTTCCTGAACCGGATCGACGAAATCGTGATCTTCCATTCCCTGGAGAAGGAGCACTTGATCCACATCCTC
GATATCCTGCTGCACGAACTGAATCTCCGCCTGATCGACAAGAGCGTCAGCATCGAGGTGGACGACGAAGTGAAACAGTG
GCTCATCAAGGAAGGATACGAGCCGCTCTACGGTGCGCGCCCGATGCGCCGCATCATCCAACGGGCGATCGGCGATCCCC
TGTCTGAAGAACTCATCAAGGGTCGCTTCAAGGAGAACCGGAAGATCAAAGTCGTGCTGCGCGACGGCGCGCCGGCCTTT
ATCGAGCAGGAAGCGATGGCGGGCGTCTAG

Protein sequence :
MFERFTDKGRKIIILAREEAERHQNDYLGTEHLVLAILRETDGIALMILKKMGLSTEQIRLEIERNLPGGGTTMTFGEIP
FSPRVKKVIEYGVEEARLLGHNHIGSEHLLLGLLREEEGIGGKILRSLGANLLTARQLTVTFLRKSAPRERDRKSNTPAL
DEFGRDLTQLAQEGQLDPVIGRADEIERVLQILSRRSKNNPVLIGESGVGKTAIVEGLAQRIIASEVPDNLLSRRVIALD
LGSLVAGTKYRGQFEERLKVVMKEIVQAGNIIIFIDELHTLVGAGAAEGSIDASNMLKPALSRGEIQCIGATTLDEYRKH
IEKDGALKRRFQPIHVQPPSTDETVRIIQGLRDRYEEHHGVEITEDAIVEAVKLADRYITDRFLPDKAIDLIDETGSRAK
LQTYALPTELKALEQELKKISRDKELAISMQNFEEAVRHREEEERLRKLLDESKREWKKNQEKHKPTIGKEEVAYVVSKM
TGIPLFKLEEEESNKLLRMEEFLHKRVIGQNEAISAVARAIRRSRAGLKEAKKPIGSFIFLGPTGVGKTELARTLAEFLF
NSEDALIRIDMSEYQEKFTSSRLFGAPPGYVGYEEGGQLTEKVRRRPYSVVLFDEIEKAHPDVFNVLLQVLDDGVLTDSL
GRKVDFKNTVVIMTSNIGTKMIQKGVSLGFQNDEKGGQALRRKEDVMGELKRSFSPEFLNRIDEIVIFHSLEKEHLIHIL
DILLHELNLRLIDKSVSIEVDDEVKQWLIKEGYEPLYGARPMRRIIQRAIGDPLSEELIKGRFKENRKIKVVLRDGAPAF
IEQEAMAGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB3 YP_003798092.1 chaperone protein ClpB VFG0079 Protein 0.0 56
clpB3 YP_003798092.1 chaperone protein ClpB VFG0080 Protein 4e-138 52